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Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene among Malay male hypertensive subjects in response to ACE inhibitors
Conclusion: Patients carrying the DD genotype had higher blood pressure-lowering response when treated with ACE inhibitors enalapril or lisinopril than those carrying ID and II genotypes, suggesting that the D allele may be a possible genetic marker for essential hypertension among Malay male subjects. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Heidari, F., Vasudevan, R., Mohd Ali, S. Z., Ismail, P., Etemad, A., Pishva, S. R., Othman, F., Bakar, S. A. Tags: Original Articles Source Type: research

Association of echocardiographic left ventricular structure and -344C/T aldosterone synthase gene variant: A meta-analysis
Conclusions: The present findings support the hypothesis that CC homozygous individuals may have greater left ventricular diameters (LVEDD and LVESD) regardless of their ethnicities or physical conditions. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Wang, L., Zhou, J., Zhang, B., Wang, H., Li, M., Niu, Q., Chen, Y., Chen, R., Wen, S. Tags: Original Articles Source Type: research

Association of angiotensin II type 1 receptor (A1166C) polymorphism with breast cancer risk: An update meta-analysis
Conclusion: We concluded that AT1R gene A1166C polymorphism was associated with reduced risk for breast cancer. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Chen, F., Chen, G., Dou, Y., Xu, X. Tags: Original Articles Source Type: research

Association of ACE insertion or deletion polymorphisms with the risk of coronary restenosis after percutaneous coronary intervention: A meta-analysis
Conclusions: The present study suggested that the ACE gene I/D polymorphism was associated with coronary restenosis, regardless of age and ethnicity. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Miao, H.-W., Gong, H. Tags: Original Articles Source Type: research

Association of ACE and MTHFR genetic polymorphisms with type 2 diabetes mellitus: Susceptibility and complications
Conclusions: The MTHFR 677 TT genotype was associated with T2DM susceptibility and complications (DR, DPN and IHD). The MTHFR 1298 CC, AC and ACE DD genotypes were associated with DR and DPN. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Settin, A., El-Baz, R., Ismaeel, A., Tolba, W., Allah, W. A. Tags: Original Articles Source Type: research

Association between apolipoprotein B gene polymorphisms and the risk of coronary heart disease (CHD): an update meta-analysis
Conclusion: The current meta-analysis found an association of EcoRI polymorphism and SpIns/Del polymorphism with an increased risk of CHD. No significant association between apoB XbaI polymorphism and CHD we observed in the present study. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Zhang, J.-Z., Zheng, Y.-Y., Yang, Y.-N., Li, X.-M., Fu, Z.-Y., Dai, C.-F., Liu, F., Chen, B.-D., Gai, M.-T., Ma, Y.-T., Xie, X. Tags: Original Articles Source Type: research

Association between angiotensin-converting enzyme gene insertion/deletion polymorphism and pancreatitis risk: A meta-analysis
Conclusions: According to the results of our meta-analysis, the ACE I/D polymorphism probably associates with pancreatitis risk, especially acute pancreatitis risk, with the I allele acting as a risk factor. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Fang, F., Pan, J., Xu, L., Su, G., Li, G., Wang, J. Tags: Original Articles Source Type: research

Assessment of the relationship between ACE I/D gene polymorphism and renal allograft survival
Conclusions: ACE D allele and DD genotype were associated with renal allograft survival after renal transplantation in the Asian population. However, more studies should be performed to confirm this association. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Yang, C.-H., Lu, Y., Chen, X.-X., Xian, W.-F., Tu, W.-F., Li, H.-Y. Tags: Original Articles Source Type: research

Anti-stress and nootropic activity of drugs affecting the renin-angiotensin system in rats based on indirect biochemical evidence
Conclusions: The present study provides scientific support for the anti-stress and nootropic activities of aliskiren, valsartan and their combination. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Anil Kumar, K., Nagwar, S., Thyloor, R., Satyanarayana, S. Tags: Original Articles Source Type: research

Angiotensin-converting enzyme insertion/deletion gene polymorphisms associated with risk of atrial fibrillation: A meta-analysis of 23 case-control studies
Conclusions: ACE I/D gene polymorphisms and AF are significantly related to ethnicity. Individuals with the ACE D/D genotype appear to be at higher risk of AF. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Ma, R., Li, X., Su, G., Hong, Y., Wu, X., Wang, J., Zhao, Z., Song, Y., Ma, S. Tags: Original Articles Source Type: research

Angiotensin-converting enzyme I/D polymorphism and diabetic peripheral neuropathy in type 2 diabetes mellitus: A meta-analysis
Conclusions: Our meta-analysis confirmed that ACE I/D polymorphism was associated with the risk of DPN. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Li, Y., Tong, N. Tags: Original Articles Source Type: research

Angiotensin-converting enzyme I/D polymorphism and acute respiratory distress syndrome
Conclusions: This meta-analysis suggested that ACE I/D polymorphism might contribute to the susceptibility for ARDS. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Deng, X., Zhang, S., Jin, K., Li, L., Gu, W., Liu, M., Zhou, L. Tags: Original Articles Source Type: research

Angiotensin type 1 receptor mediates renal production and conversion of prostaglandins E2 to F2{alpha} in conscious diabetic rats
Conclusion: Our results suggest that in diabetes, AT1R increases PGE2 generation and reduces conversion of PGE2 to PGF2α with the progression of diabetes. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Abadir, P. M., Siragy, H. M. Tags: Original Articles Source Type: research

Angiotensin receptor blockers use and the risk of lung cancer: A meta-analysis
Conclusions: This meta-analysis indicated that ARBs may be associated with decreased risk of LC. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Zhang, W., Liang, Z., Li, J., Cai, S. Tags: Original Articles Source Type: research

Angiotensin III induces signal transducer and activator of transcription 3 and interleukin-6 mRNA levels in cultured rat astrocytes
Conclusions: These findings suggest that Ang III, similar to Ang II, has pro-inflammatory effects since it induces STAT3 leading to an induction of IL-6 mRNA expression, outcomes that lend relevance to the physiological importance of central Ang III. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Kandalam, U., Sarmiento, N., Haspula, D., Clark, M. A. Tags: Original Articles Source Type: research