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MicroRNA-155 inhibits angiotensin II-induced vascular smooth muscle cell proliferation
Conclusion: miR-155 downregulation of Ang II-induced VSMC viability identifies it as an important regulator of cell proliferation. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - June 9, 2014 Category: Biomedical Science Authors: Yang, L.-x., Liu, G., Zhu, G.-f., Liu, H., Guo, R.-w., Qi, F., Zou, J.-h. Tags: Articles Source Type: research

Binding of prorenin to (pro)renin receptor induces the proliferation of human umbilical artery smooth muscle cells via ROS generation and ERK1/2 activation
Conclusion: Binding of prorenin to PRR can induce HUASM cell proliferation via the ROS generation and ERK1/2 activation. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - June 9, 2014 Category: Biomedical Science Authors: Liu, F. Y., Liu, X. Y., Zhang, L. J., Cheng, Y. P., Jiang, Y. N. Tags: Articles Source Type: research

Renin inhibition in patients with chronic kidney disease: Is it conclusively non-indicated?
(Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - February 13, 2014 Category: Biomedical Science Authors: Sarafidis, P. A., Bakris, G. L. Tags: Letter to the Editor Source Type: research

Arginine supplementation for improving maternal and neonatal outcomes in hypertensive disorder of pregnancy: A systematic review
Conclusion: This study demonstrates L-arginine supplementation is superior to placebo in lowering diastolic pressure and prolonging pregnancy in patients with gestational hypertension with or without proteinuria, but the effect on lowering systolic pressure and increasing neonatal weight was not statistically significant. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - February 13, 2014 Category: Biomedical Science Authors: Gui, S., Jia, J., Niu, X., Bai, Y., Zou, H., Deng, J., Zhou, R. Tags: Articles Source Type: research

Cholecalciferol administration blunts the systemic renin-angiotensin system in essential hypertensives with hypovitaminosis D
Conclusions: Our data indicate that in essential hypertensives with hypovitaminosis D, pharmacological correction of vitamin D levels can blunt systemic RAS activity. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - February 13, 2014 Category: Biomedical Science Authors: Carrara, D., Bernini, M., Bacca, A., Rugani, I., Duranti, E., Virdis, A., Ghiadoni, L., Taddei, S., Bernini, G. Tags: Articles Source Type: research