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Area epidemiological research on hypertension risk factors of Keriyans in the Taklimakan Desert
Conclusions: Age, hyperglycemia and salt consumption as well as sodium intake in diet were correlated with hypertension risk factors, which leads to the speculation that the water of the desert draught area which is characterized by low calcium and high magnesium levels might account for the low incidence of hypertension in Keriyans. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Cao, H., Cheng, Z., Chen, F., Ding, Z. Tags: Original Articles Source Type: research

Angiotensin-converting enzyme insertion/deletion polymorphism associated with allergic rhinitis susceptibility: Evidence from 1410 subjects
Conclusions: The ACE I/D polymorphism may be a risk factor for AR and studies with large sample size and representative population are warranted to verify this finding. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Lin, H., Lin, D., Zheng, C.-Q. Tags: Original Articles Source Type: research

Angiotensin-converting enzyme I/D polymorphism is associated with pneumonia risk: A meta-analysis
Conclusions: Our meta-analysis confirmed that ACE I/D polymorphism was associated with pneumonia risk. However, ACE I/D polymorphism was not associated with pneumonia mortality. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Nie, W., Zang, Y., Chen, J., Liu, T., Xiao, L., Xiu, Q. Tags: Original Articles Source Type: research

Influence of ABO genotype and phenotype on angiotensin-converting enzyme plasma activity
Conclusion: These results provide new evidence for the ABO-ACE relationship. Although the genetic marker studied here may be involved somehow, ABO phenotype is shown to be a better predictor of ACE plasma activity. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Gasso, P., Ritter, M. A., Mas, S., Lafuente, A. Tags: Original Articles Source Type: research

Association of angiotensin-converting enzyme (ACE) and fatty acid binding protein 2 (FABP2) genes polymorphism with type 2 diabetes mellitus in Northern India
Conclusion: It appears that the ACE I/I genotype frequency was significantly higher in the T2DM cases as compared to the controls. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Raza, S. T., Fatima, J., Ahmed, F., Abbas, S., Zaidi, Z. H., Singh, S., Mahdi, F. Tags: Original Articles Source Type: research

Angiotensin-converting enzyme gene insertion/deletion polymorphism studies in Asian Indian pregnant women biochemically identifies gestational diabetes mellitus
Conclusion: ACE gene polymorphism was associated with GDM in Asian Indian pregnant women. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Khan, I. A., Jahan, P., Hasan, Q., Rao, P. Tags: Original Articles Source Type: research

Renin-angiotensin system genetic polymorphisms: Lack of association with CRP levels in patients with coronary artery disease
In conclusion, genetic polymorphisms of RAS are not associated with increased serum CRP in CAD. Compensation of an increased activity of ACE through counter-regulation and the secretion of CRP under the influence of Ang II in the vessel being local could explain the lack of association between the studied polymorphisms and CRP levels in CAD patients. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Bahramali, E., Firouzabadi, N., Jonaidi-Jafari, N., Shafiei, M. Tags: Original Articles Source Type: research

Association of aldosterone synthase (CYP11B2) gene -344T/C polymorphism with the risk of primary chronic glomerulonephritis in the Polish population
Conclusion: Our results suggest that the CYP11B2 –344C/T polymorphism might be an independent risk factor of IgAN, FSGS and all proliferative chronic GNs. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Pawlik, M., Mostowska, A., Lianeri, M., Oko, A., Jagodziłski, P. P. Tags: Original Articles Source Type: research

Gender difference of serum angiotensin-converting enzyme (ACE) activity in DD genotype of ACE insertion/deletion polymorphism in elderly Chinese
Conclusions: No significant gender difference of genotype distribution was found in elderly Chinese. Serum ACE activity was significantly correlated with ACE I/D polymorphism in elderly Chinese. Male subjects with DD genotype had higher serum ACE activity than female subjects with DD genotype. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Zhang, Y.-F., Cheng, Q., Tang, N. L., Chu, T. T., Tomlinson, B., Liu, F., Kwok, T. C. Tags: Original Articles Source Type: research

A core promoter variant of angiotensinogen gene and interindividual variation in response to angiotensin-converting enzyme inhibitors
Conclusion: Our study indicates that the A-6G variant of the AGT gene may be an important determinant of interindividual variation in the response to ACE inhibitors. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Yu, H., Lin, S., Zhong, J., He, M., Jin, L., Zhang, Y., Liu, G. Tags: Original Articles Source Type: research

Effects of renal sympathetic denervation using saline-irrigated radiofrequency ablation catheter on the activity of the renin-angiotensin system and endothelin-1
Conclusion: RDN substantially decreased BP and also significantly decreased the plasma levels of RAS and ET-1, which might be implicated in the mechanism of BP reduction by RDN. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Lu, J., Ling, Z., Chen, W., Du, H., Xu, Y., Fan, J., Long, Y., Chen, S., Xiao, P., Liu, Z., Zrenner, B., Yin, Y. Tags: Original Articles Source Type: research

The balance between human maternal plasma angiotensin II and angiotensin 1-7 levels in early gestation pregnancy is influenced by fetal sex
Conclusions: In early human pregnancy, the maternal RAS is influenced by fetal sex. The lower Ang 1-7 to Ang II ratios in women with female fetuses may contribute to the lower maternal peripheral microvascular flow as described previously and the lack of any positive effect of Ang II on fetal growth, as seen in women with male fetuses. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Sykes, S. D., Pringle, K. G., Zhou, A., Dekker, G. A., Roberts, C. T., Lumbers, E. R., on behalf of the SCOPE Consortium Tags: Original Articles Source Type: research

Aliskiren and losartan trial in non-diabetic chronic kidney disease
Conclusion: This study in non-diabetic CKD patients showed that combination therapy with aliskiren and ARB was as efficacious as aliskiren alone and ARB alone. There was one patient who developed a non-fatal stroke in the combined aliskiren and ARB group while the other two groups had none. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Woo, K.-T., Choong, H.-L., Wong, K.-S., Tan, H.-K., Foo, M., Fook-Chong, S., Lee, E. J., Anantharaman, V., Lee, G. S., Chan, C.-M. Tags: Original Articles Source Type: research

Circadian rhythm of urinary potassium excretion during treatment with an angiotensin receptor blocker
Conclusions: The circadian rhythm of UKV was determined by the rhythm of UNaV even during ARB treatment. Changes in the circadian UKV rhythm were not determined by aldosterone but by UNaV. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Ogiyama, Y., Miura, T., Watanabe, S., Fuwa, D., Tomonari, T., Ota, K., Kato, Y., Ichikawa, T., Shirasawa, Y., Ito, A., Yoshida, A., Fukuda, M., Kimura, G. Tags: Original Articles Source Type: research

Circadian rhythm of plasma and urinary angiotensinogen in healthy volunteers and in patients with chronic kidney disease
The urinary angiotensinogen (AGT) excretion rate could be a novel biomarker for the intrarenal activity of the renin-angiotensin system. Little is known about the circadian rhythm of AGT levels in plasma or urine. In this short article, making use of data in plasma and urine of healthy volunteers and patients with chronic kidney diseases, we first report that we were unable to find evidence for a circadian rhythm of AGT under any condition. Next we critically discuss to what degree elevated urinary AGT levels might be considered an independent biomarker that is not simply the non-specific consequence of proteinuria. (Sourc...
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Nishijima, Y., Kobori, H., Kaifu, K., Mizushige, T., Hara, T., Nishiyama, A., Kohno, M. Tags: Original Articles Source Type: research