The balance between human maternal plasma angiotensin II and angiotensin 1-7 levels in early gestation pregnancy is influenced by fetal sex

Conclusions:
In early human pregnancy, the maternal RAS is influenced by fetal sex. The lower Ang 1-7 to Ang II ratios in women with female fetuses may contribute to the lower maternal peripheral microvascular flow as described previously and the lack of any positive effect of Ang II on fetal growth, as seen in women with male fetuses.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 12, 2014 Category: Biomedical Science Authors: Sykes, S. D., Pringle, K. G., Zhou, A., Dekker, G. A., Roberts, C. T., Lumbers, E. R., on behalf of the SCOPE Consortium Tags: Original Articles Source Type: research