The microRNA-132/212 family fine-tunes multiple targets in Angiotensin II signalling in cardiac fibroblasts

Conclusion:
We here report novel insight of an extensive network of molecular pathways that fine-tuned by miR-132/212, suggesting a role for this miRNA family as master signalling switches in cardiac fibroblasts. Our data underscore the potential for miRNA tools to manipulate a large array of molecules and thereby control biological function.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Eskildsen, T. V., Schneider, M., Sandberg, M. B., Skov, V., Bronnum, H., Thomassen, M., Kruse, T. A., Andersen, D. C., Sheikh, S. P. Tags: Original Articles Source Type: research