Susceptibility of Stenotrophomonas maltophilia Clinical Isolates to Antibiotics and Contact Lens Multipurpose Disinfecting Solutions [Cornea]
Conclusions.
The Australian ocular isolates of S. maltophilia remain susceptible to trimethoprim-sulfamethozole, tigecycline, and most fluoroquinolones. However, the isolates showed resistance to certain multipurpose disinfecting solutions. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 29, 2014 Category: Opthalmology Authors: Watanabe, K., Zhu, H., Willcox, M. Tags: Cornea Source Type: research
Change of Recipient Corneal Endothelial Cells After Non-Descemet's Stripping Automated Endothelial Keratoplasty in a Rabbit Model [Cornea]
Conclusions.
After non-Descemet's stripping automated endothelial keratoplasty, the CEEB showed decreased density, loss of pump function, apoptosis and changed morphology. However, the interface opacity was not significantly greater compared with DSAEK eyes. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 29, 2014 Category: Opthalmology Authors: Sun, J.-P., Hu, F.-R., Chen, Y.-M., Chu, H.-S., Chen, W.-L. Tags: Cornea Source Type: research
Developing an Instrumental Activities of Daily Living Tool as Part of the Low Vision Assessment of Daily Activities Protocol [Low Vision]
Conclusions.
Using a large item pool, participant, and expert input, as well as factor and Rasch analysis, we designed a valid and reliable assessment to measure vision-related IADL performance in persons with severe vision loss. This assessment tool can be used in clinical sight restoration trials. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 29, 2014 Category: Opthalmology Authors: Finger, R. P., McSweeney, S. C., Deverell, L., O'Hare, F., Bentley, S. A., Luu, C. D., Guymer, R. H., Ayton, L. N. Tags: Low Vision Source Type: research
Flow Behavior of Heavy Silicone Oil During Eye Movements [Retina]
Conclusions.
The viscosity of HSO is not the sole parameter with which to determine the behavior of HSO during eye movements. Various HSOs that are manufactured by mixing different types of base SO and "heavy" additives show distinct flow behaviors. The solubility and stability of the heavy additives in the base SO alter its flow when subjected to eye movements, which may contribute to in vivo emulsification. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 29, 2014 Category: Opthalmology Authors: Chan, Y. K., Williams, R. L., Wong, D. Tags: Retina Source Type: research
Quantitative Assessment of the Human Retinal Microvasculature With or Without Vascular Comorbidity [Retina]
Conclusions.
Cardiovascular comorbidities may be associated with changes to the capillary density within the human retinal microvasculature, before the manifestation of known ocular diseases. These differences in capillary density may have important correlations with neuronal function and facilitates the basis of understanding pathogenic mechanisms in retinal vascular disease. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 29, 2014 Category: Opthalmology Authors: Tan, P. E. Z., Yu, P. K., Cringle, S. J., Yu, D.-Y. Tags: Retina Source Type: research
Population-Based Evaluation of Retinal Nerve Fiber Layer, Retinal Ganglion Cell Layer, and Inner Plexiform Layer as a Diagnostic Tool For Glaucoma [Retina]
Conclusions.
Macular RGCL loss is at least as common as peripapillary RNFL abnormalities in population-based glaucoma cases. Screening for glaucoma using OCT-derived regional thickness identifies approximately half of those cases of glaucoma as diagnosed by perimetry. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 29, 2014 Category: Opthalmology Authors: Springelkamp, H., Lee, K., Wolfs, R. C. W., Buitendijk, G. H. S., Ramdas, W. D., Hofman, A., Vingerling, J. R., Klaver, C. C. W., Abramoff, M. D., Jansonius, N. M. Tags: Retina Source Type: research
Epiretinal Membrane Inflammatory Cell Density Might Reflect the Activity of Proliferative Diabetic Retinopathy [Immunology and Microbiology]
Conclusions.
Lymphocyte infiltration of FVMs might be associated with the activity of retinopathy but not with visual acuity improvement after surgery. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Urbančič, M., Štunf, Špela, MilutinovićŽivin, A., Petrovič, D., GlobočnikPetrovič, M. Tags: Immunology and Microbiology Source Type: research
Potential Benefits of Mathematical Models to Predict Endothelial Cell Density Following Penetrating Keratoplasty [Research Highlight]
(Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Binder, P. S. Tags: Research Highlight Source Type: research
A Mathematical Model to Predict Endothelial Cell Density Following Penetrating Keratoplasty With Selective Dropout From Graft Failure [Cornea]
Conclusions.
Endothelial cell loss after PK can be modeled via a log-polynomial model, which accounts for the correlated data from repeated measures on the same subject. This model is not significantly affected by the selective dropout due to graft failure. Our findings warrant further study on how this may extend to ECD following endothelial keratoplasty. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Riddlesworth, T. D., Kollman, C., Lass, J. H., Patel, S. V., Stulting, R. D., Benetz, B. A., Gal, R. L., Beck, R. W. Tags: Cornea Source Type: research
Endothelial Nitric Oxide Synthase-Related Mechanotransduction Changes in Aged Porcine Angular Aqueous Plexus Cells [Glaucoma]
Conclusions.
Aged AAP cells appear compromised in their mechanotransduction machinery involving eNOS, the protein product of the gene, NOS3, polymorphisms of which impart a risk for the development of glaucoma. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Lei, Y., Stamer, W. D., Wu, J., Sun, X. Tags: Glaucoma Source Type: research
Endothelial Approach Ultrathin Corneal Grafts Prepared by Femtosecond Laser for Descemet Stripping Endothelial Keratoplasty [Cornea]
Conclusions.
The corneal endothelial grafts prepared by LDV femtosecond laser with endothelial approach produced consistently ultrathin grafts in uniform shape with high accuracy and good endothelial and stromal interface quality. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Liu, Y.-C., Teo, E. P. W., Adnan, K. B., Yam, G. H. F., Peh, G. S. L., Tan, D. T.- H., Mehta, J. S. Tags: Cornea Source Type: research
A New Approach to Measure Visual Field Progression in Glaucoma Patients Using Variational Bayes Linear Regression [Glaucoma]
Conclusions.
The VBLR more accurately predicts future VF progression in glaucoma patients compared to conventional OLSLR, especially in short VF series. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Murata, H., Araie, M., Asaoka, R. Tags: Glaucoma Source Type: research
Quantitative Analysis of Collagen Lamellae in the Normal and Keratoconic Human Cornea by Second Harmonic Generation Imaging Microscopy [Cornea]
Conclusions.
In the normal human cornea, collagen lamellae adjacent to BL are narrow and form a steep angle with BL, whereas they increase in width and their angle relative to BL flattens with progression toward DM. These properties of collagen lamellae are altered in keratoconus and are likely related to abnormalities of corneal shape. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Morishige, N., Shin-gyou-uchi, R., Azumi, H., Ohta, H., Morita, Y., Yamada, N., Kimura, K., Takahara, A., Sonoda, K.-H. Tags: Cornea Source Type: research
Corneal Cross-Linking in Keratoconus Using the Standard and Rapid Treatment Protocol: Differences in Demarcation Line and 12-Month Outcomes [Cornea]
Conclusions.
The rapid CXL protocol negatively influences the occurrence and depth of the demarcation line 1 month after CXL. Our results show a negative effect on the topographical outcome 1 year after CXL. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Brittingham, S., Tappeiner, C., Frueh, B. E. Tags: Cornea Source Type: research
Square Wave Jerks and Anxiety as Distinctive Biomarkers for Anorexia Nervosa [Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology]
Conclusions.
Given our current understanding of saccadic eye movements, the findings suggest a potential role of -aminobutyric acid (GABA) in the superior colliculus, frontal eye fields, or posterior parietal cortex in the psychopathology of AN. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - December 23, 2014 Category: Opthalmology Authors: Phillipou, A., Rossell, S. L., Castle, D. J., Gurvich, C., Abel, L. A. Tags: Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology Source Type: research
