Differential propensity of citrate- and polyethylene glycol-coated silver nanoparticles to bovine hemoglobin
Propensity of two different silver nanoparticles (Ag-NPs) to bovine hemoglobin (BHb) was investigated by means of spectroscopic methods. We have combined spectrophotometric and calorimetric methods to show that there is no significant interaction between citrate-coated Ag-NPs and BHb at physiological pH and 20°C. However, our previous results show that polyethylene glycol-coated Ag-NPs strongly bind to Hb and effect on the secondary and tertiary structures of BHb. Thus, a suitable surface coating and modification of surface charge would increase the NPs safety and reduce adverse biological responses. (Source: Toxicolog...
Source: Toxicology and Industrial Health - July 31, 2015 Category: Toxicology Authors: Zolghadri, S., Saboury, A. A., Atri, M. S., Moosavi-Movahedi, A. Tags: Articles Source Type: research
Randomly amplified polymorphic-DNA analysis for detecting genotoxic effects of Boron on maize (Zea mays L.)
This study was carried out to investigate the genotoxic effect of boron (B) on maize using randomly amplified polymorphic DNA (RAPD) method. Experimental design was conducted under 0, 5, 10, 25, 50, 100, 125, and 150 ppm B exposures, and physiological changes have revealed a sharp decrease in root growth rates from 28% to 85%, starting from 25 ppm to 150 ppm, respectively. RAPD-polymerase chain reaction (PCR) analysis shows that DNA alterations are clearly observed from beginning to 100 ppm. B-induced inhibition in root growth had a positive correlation with DNA alterations. Total soluble protein, root and s...
Source: Toxicology and Industrial Health - July 31, 2015 Category: Toxicology Authors: Sakcali, M. S., Kekec, G., Uzonur, I., Alpsoy, L., Tombuloglu, H. Tags: Articles Source Type: research
Beneficial influence of topical extra virgin olive oil application on an experimental model of penile fracture in rats
In this study, we aimed to investigate the healing influence of topical extra virgin olive oil (EVOO) on PF through evaluating levels of some oxidative stress biomarkers for the first time. Histopathological evaluation was also realized. A total of 18 male Sprague-Dawley albino rats were divided into three groups of six rats each as control group, in PF (alone) group, and PF + EVOO group. Experimental PF was formed via incising from the proximal dorsal side of the penis in the rats of all groups except control. While in PF (alone) group, fracture was formed and the incision was primarily closed, in PF + ...
Source: Toxicology and Industrial Health - July 31, 2015 Category: Toxicology Authors: Gunes, M., Ozkol, H., Pirincci, N., Gecit, I., Bilici, S., Yildirim, S. Tags: Articles Source Type: research
Antimutagenic and genoprotective effects of Saraca asoca bark extract
Conclusion:
The study clearly reveals the antimutagenic and antigenotoxic properties of SAE. (Source: Toxicology and Industrial Health)
Source: Toxicology and Industrial Health - July 31, 2015 Category: Toxicology Authors: Nag, D., Ghosh, M., Mukherjee, A. Tags: Articles Source Type: research
Ophthalmic findings in acute mercury poisoning in adults: A case series study
The aim of this study is to report ophthalmic findings of acute mercury poisoning in 48 adults referred to emergency department. Full ophthalmologic examination including the best corrected visual acuity, external eye examination, reaction to light, a slit-lamp examination, funduscopy, intraocular pressure measurements, and visual field (VF) and color vision (CV) tests were performed at the presentation and repeated after 6 months. The parametric values of VF test, the mean deviation (MD), and pattern standard deviation (PSD) were recorded in order to compare patients and the 30 healthy controls. The mean parameter of colo...
Source: Toxicology and Industrial Health - July 31, 2015 Category: Toxicology Authors: Aslan, L., Aslankurt, M., Bozkurt, S., Aksoy, A., Ozdemir, M., Gizir, H., Yasar, I. Tags: Articles Source Type: research
