Patients with Obstructive Sleep Apnea Have Cardiac Repolarization Disturbances when Travelling to Altitude: Randomized, Placebo-Controlled Trial of Acetazolamide
Conclusions:At 2590 m OSA patients experienced cardiac repolarization disturbances in association with hypoxemia. Prolongation of meanQTc at altitude was prevented and hypoxemia was improved by acetazolamide, whereas maxQTc remained increased suggesting imperfect protection from repolarization disturbances.Clinical Trial Registration:ClinicalTrials.gov ID: NTC-00714740. URL:www.clinicaltrials.govCitation:Latshang TD, Kaufmann B, Nussbaumer-Ochsner Y, Ulrich S, Furian M, Kohler M, Thurnheer R, Saguner AM, Duru F, Bloch KE. Patients with obstructive sleep apnea have cardiac repolarization disturbances when travelling to alti...
Source: Sleep - August 31, 2016 Category: Sleep Medicine Source Type: research
Is Sleep Quality More Important than Sleep Duration for Public Health?
(Source: Sleep)
Source: Sleep - August 31, 2016 Category: Sleep Medicine Source Type: research
Age-Related Reduction of Recovery Sleep and Arousal Threshold in Drosophila
Conclusions: < /h3 > < p id="d7e155" > Further studies are certainly needed, but we suggest that the lower homeostatic sleep drive of older flies causes their decreased arousal threshold. < /p > < /div > < div class="section" > < a name="d7e157" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e160" > Vienne J, Spann R, Guo F, Rosbash M. Age-related reduction of recovery sleep and arousal threshold in < i > Drosophila. SLEEP < /i > 2016;39(8):1613 & #8211;1624. < /p > < /div > < /div > (Source: Sleep)
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Intermittent Short Sleep Results in Lasting Sleep Wake Disturbances and Degeneration of Locus Coeruleus and Orexinergic Neurons
Conclusions: < /h3 > < p id="d7e149" > Collectively these findings demonstrate for the first time that ISS imparts significant lasting disturbances in sleep/wake activity, degeneration of wake-activated LC and orexinergic neurons, and lasting metabolic changes in remaining neurons most consistent with premature senescence. < /p > < /div > < div class="section" > < a name="d7e151" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e154" > Zhu Y, Fenik P, Zhan G, Somach R, Xin R, Veasey S. Intermittent short sleep results in lasting sleep wake disturbances and degeneration of locus coer...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Effect of Slow Wave Sleep Disruption on Metabolic Parameters in Adolescents
Conclusion: < /h3 > < p id="d7e236" > Pubertal children across a range of body mass indices may be resistant to the adverse metabolic effects of acute SWS disruption. Only those subjects with high SI (i.e., having the greatest & #8220;metabolic reserve & #8221;) demonstrated a consistent decrease in SI. These results suggest that adolescents may have a unique ability to adapt to metabolic stressors, such as acute SWS disruption, to maintain euglycemia. Additional studies are necessary to confirm that this resiliency is maintained in settings of chronic SWS disruption. < /p > < /div > < div class="section" > < a name="d7e23...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Polysomnographic Measurement of Sleep Duration and Bodily Pain Perception in the Sleep Heart Health Study
Conclusions: < /h3 > < p id="d7e179" > Shorter TST among all subjects and shorter SWS time in men was associated with & #8220;moderate to severe pain. & #8221; REM sleep time was not associated with bodily pain perception in this cohort. < /p > < /div > < div class="section" > < a name="d7e181" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e184" > Weingarten JA, Dubrovsky B, Basner RC, Redline S, George L, Lederer DJ. Polysomnographic measurement of sleep duration and bodily pain perception in the Sleep Heart Health Study. < i > SLEEP < /i > 2016;39(8):1583 & #8211;1589. < /p > ...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Cost-Effectiveness of Group and Internet Cognitive Behavioral Therapy for Insomnia in Adolescents: Results from a Randomized Controlled Trial
Conclusions: < /h3 > < p id="d7e124" > Internet CBTI is a cost-effective treatment compared to group CBTI for adolescents, although effects were largely similar for both formats. Further studies in a clinical setting are warranted. < /p > < /div > < div class="section" > < a name="d7e126" > < !-- named anchor -- > < /a > < h3 class="section-title" > Clinical Trial Registration: < /h3 > < p id="d7e129" > ID: ISRCTN33922163; trial name: Effectiveness of cognitive behavioral therapy for sleeplessness in adolescents; URL: < a target="xrefwindow" href="http://www.isrctn.com/ISRCTN33922163" id="d7e131" > http://www.isrctn.com/IS...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Emergence of Sex Differences in Insomnia Symptoms in Adolescents: A Large-Scale School-Based Study
Conclusions: < /h3 > < p id="d7e235" > Pubertal maturation was associated with a progressive increase in the prevalence of insomnia symptoms with the emergence of female preponderance in both the prevalence and severity of insomnia symptoms at late puberty. < /p > < /div > < div class="section" > < a name="d7e237" > < !-- named anchor -- > < /a > < h3 class="section-title" > Clinical Trials Registration: < /h3 > < p id="d7e240" > Chinese Clinical Trial Register, < a target="xrefwindow" href="http://www.chictr.org.cn" id="d7e242" > http://www.chictr.org.cn < /a > , ID: ChiCTR-TRC-12002798 < /p > < /div > < div class="sectio...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Sleep Duration Associated with the Lowest Risk of Depression/Anxiety in Adolescents
Conclusions: < /h3 > < p id="d7e166" > Sleep duration of & #8805; 8.5 h on school nights may be associated with the lowest risk of depression/anxiety on average in male adolescents. Although the duration was estimated to be shorter in females ( & #8805; 7.5 h) than males, this should be interpreted carefully. Most adolescents may currently be sleeping less than the optimal duration. < /p > < /div > < div class="section" > < a name="d7e168" > < !-- named anchor -- > < /a > < h3 class="section-title" > Commentary: < /h3 > < p id="d7e171" > A commentary on this article appears in this issue on page 1491. < /p > < /div > < div...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
The Manifestations of Sleep Disturbances 16 Years Post-Trauma
Conclusions: < /h3 > < p id="d7e212" > Our data indicate a chronicity of PTSD-related sleep disturbances, particularly among childhood trauma survivors. REM sleep disturbances may have different manifestations depending on the developmental stage at the time of trauma exposure. < /p > < /div > < div class="section" > < a name="d7e214" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e217" > Thordardottir EB, Hansdottir I, Valdimarsdottir UA, Shipherd JC, Resnick H, Gudmundsdottir B. The manifestations of sleep disturbances 16 years post-trauma. < i > SLEEP < /i > 2016;39(8):1551 & ...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Mortality and Its Risk Factors in Patients with Rapid Eye Movement Sleep Behavior Disorder
Conclusions: < /h3 > < p id="d7e243" > Patients with RBD have a higher mortality rate than the general population only if neurodegenerative diseases develop. Several risk factors on clinical and sleep aspects are associated with mortality in RBD patients. Our findings underscore the necessity of timely neuroprotective interventions in the early phase of RBD before the development of neurodegenerative diseases. < /p > < /div > < div class="section" > < a name="d7e245" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e248" > Zhou J, Zhang J, Lam SP, Mok V, Chan A, Li SX, Liu Y, Tang X...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Familial Kleine-Levin Syndrome: A Specific Entity?
Conclusion: < /h3 > < p id="d7e206" > Familial KLS is mostly present in the same generation, and is clinically similar to but slightly less severe than sporadic KLS. < /p > < /div > < div class="section" > < a name="d7e208" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e211" > Nguyen QT, Groos E, Leclair-Visonneau L, Monaca-Charley C, Rico T, Farber N, Mignot E, Arnulf I. Familial Kleine-Levin syndrome: a specific entity? < i > SLEEP < /i > 2016;39(8):1535 & #8211;1542. < /p > < /div > < /div > (Source: Sleep)
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Sleep and Cognitive Function in Multiple Sclerosis
Conclusions: < /h3 > < p id="d7e166" > Among patients with MS, obstructive sleep apnea and sleep disturbance are significantly associated with diminished visual memory, verbal memory, executive function (as reflected by response inhibition), attention, processing speed, and working memory. If sleep disorders degrade these cognitive functions, effective treatment could offer new opportunities to improve cognitive functioning in patients with MS. < /p > < /div > < div class="section" > < a name="d7e168" > < !-- named anchor -- > < /a > < h3 class="section-title" > Commentary: < /h3 > < p id="d7e171" > A commentary on this ar...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Comparison of Sleep Disorders between Real and Simulated 3,450-m Altitude
Conclusions: < /h3 > < p id="d7e221" > Our results suggest that HH has a greater effect on nocturnal breathing and sleep structure than NH. In HH, we observed more periodic breathing, which might arise from the lower saturation due to hypobaria, but needs to be confirmed. < /p > < /div > < div class="section" > < a name="d7e223" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e226" > Heinzer R, Saugy JJ, Rupp T, Tobback N, Faiss R, Bourdillon N, Rubio JH, Millet GP. Comparison of sleep disorders between real and simulated 3,450-m altitude. < i > SLEEP < /i > 2016;39(8):1517 & #821...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
Automatic Video Analysis for Obstructive Sleep Apnea Diagnosis
Conclusions: < /h3 > < p id="d7e241" > SleepWise was reasonably accurate for noninvasive and automatic diagnosis of OSA in outpatients. SleepWise determined the severity of OSA with high reliability. The current study including simultaneous laboratory PSG and SleepWise processing image is proposed as a reasonable validation standard. < /p > < /div > < div class="section" > < a name="d7e243" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e246" > Abad J, Mu & ntilde;oz-Ferrer A, Cervantes MA, Esquinas C, Marin A, Mart & iacute;nez C, Morera J, Ruiz J. Automatic video analysis for ob...
Source: Sleep - July 30, 2016 Category: Sleep Medicine Source Type: research
