Short- and Long-Term Sleep Stability in Insomniacs and Healthy Controls
Conclusions:
Sleep duration variables, particularly total sleep time based on 3 consecutive nights in both patients with insomnia and controls or two single-night recordings separated by several years, are stable and reflect a person's habitual sleep. Furthermore, a single night in the laboratory may be useful for reliably classifying one's sleep duration.
Citation:
Gaines J, Vgontzas AN, Fernandez-Mendoza J, Basta M, Pejovic S, He F, Bixler EO. Short- and long-term sleep stability in insomniacs and healthy controls. SLEEP 2015;38(11):1727–1734. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research
End-Tidal Carbon Dioxide Measurement during Pediatric Polysomnography: Signal Quality, Association with Apnea Severity, and Prediction of Neurobehavioral Outcomes
Conclusions:Among children with suspected obstructive sleep apnea syndrome, overnight end-tidal carbon dioxide (EtCO2) levels are weakly to modestly correlated with other polysomnographic indices and therefore provide independent information on hypoventilation. EtCO2 levels improve with adenotonsillectomy but are not as responsive as AHI and do not provide independent prediction of cognitive or behavioral response to surgery.Clinical Trial Registration:Childhood Adenotonsillectomy Study for Children with OSAS (CHAT). ClinicalTrials.gov Identifier #NCT00560859.Citation:Paruthi S, Rosen CL, Wang R, Weng J, Marcus CL, Chervin...
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research
Identification of Sleep-Modulated Pathways Involved in Neuroprotection from Stroke
Conclusion:
Our data indicate that sleep deprivation before stroke reprogrammed the signaling response to injury. The inhibition of cell cycle regulation and inflammation are neuroprotective mechanisms reported also for other forms of preconditioning treatment, whereas the implication of the neuroendocrine function is novel and has never been described before. These results therefore provide new insights into neuroprotective mechanisms involved in ischemic tolerance mechanisms.
Citation:
Pace M, Baracchi F, Gao B, Bassetti C. Identification of sleep-modulated pathways involved in neuroprotection from stroke. SLEEP 2015;3...
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research
Associations between Cardioembolic Stroke and Obstructive Sleep Apnea
Conclusions:There appears to be a strong association between obstructive sleep apnea (OSA) and cardioembolic (CE) stroke. In patients with OSA presenting with cryptogenic stroke, high clinical suspicion for CE is warranted. This may lead to consideration of diagnostic studies to identify CE risk factors such as paroxysmal atrial fibrillation (AF). CE strokes are more common in patients with OSA even after adjusting for AF. This finding may reflect a high rate of occult paroxysmal AF in this population; alternatively, OSA may lead to CE strokes through mechanisms independent of AF.Citation:Lipford MC, Flemming KD, Calvin AD...
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research
Pain in Sleepwalking: A Clinical Enigma
Conclusion:Our results highlight the clinical enigma of pain in sleepwalking patients with complaints of frequent chronic pain, migraine, and headache during wakefulness but who report retrospectively experience of analgesia during severe parasomnia episodes, suggesting a relationship between dissociated brain activity and nociceptive dysregulation.Citation:Lopez R, Jaussent I, Dauvilliers Y. Pain in sleepwalking: a clinical enigma. SLEEP 2015;38(11):1693–1698. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research
