A Step Forward for Better Interpreting the Apnea-Hypopnea Index
(Source: Sleep)
Source: Sleep - December 1, 2015 Category: Sleep Medicine Source Type: research

Is Sleep Health a Potential Pathway to Global Mental Health?
(Source: Sleep)
Source: Sleep - December 1, 2015 Category: Sleep Medicine Source Type: research

Sleep, Sleep Alterations, Stress—Combined Effects on Memory?
(Source: Sleep)
Source: Sleep - December 1, 2015 Category: Sleep Medicine Source Type: research

With Appreciation and Encouragement!
(Source: Sleep)
Source: Sleep - December 1, 2015 Category: Sleep Medicine Source Type: research

Erratum
(Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

Sleep Deprivation and Time-Based Prospective Memory
Conclusions:The results highlight the potential dangerous effects of total sleep deprivation on human behavior, particularly the ability to perform an intended action after a few minutes. Sleep deprivation strongly compromises time-based prospective memory compliance but does not affect time check frequency. Sleep deprivation may impair the mechanism that allows the integration of information related to time monitoring with the prospective intention.Citation:Esposito MJ, Occhionero M, Cicogna P. Sleep deprivation and time-based prospective memory. SLEEP 2015;38(11):1823–1826. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

Measuring Acceptance of Sleep Difficulties: The Development of the Sleep Problem Acceptance Questionnaire
Conclusions:The Sleep Problem Acceptance Questionnaire (SPAQ), containing the subscales “Activity Engagement” and “Willingness”, is a valid tool to assess acceptance of insomnia.Citation:Bothelius K, Jernelöv S, Fredrikson M, McCracken LM, Kaldo V. Measuring acceptance of sleep difficulties: the development of the sleep problem acceptance questionnaire. SLEEP 2015;38(11):1815–1822. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

On-the-Road Driving Performance the Morning after Bedtime Use of Suvorexant 20 and 40 mg: A Study in Non-Elderly Healthy Volunteers
Conclusions:As assessed by mean changes in standard deviation of lateral position (SDLP), there was no clinically meaningful residual effect of suvorexant in doses of 20 and 40 mg on next-morning driving (9 h after bedtime dosing) in healthy subjects < 65 years old. There may be some individuals who experience next-day effects, as suggested by individual changes in SDLP and prematurely stopped tests.Clinical Trial Registration:clinicaltrials.gov NCT01311882.Citation:Vermeeren A, Sun H, Vuurman EF, Jongen S, Van Leeuwen CJ, Van Oers AC, Palcza J, Li X, Laethem T, Heirman I, Bautmans A, Troyer MD, Wrishko R, McCrea J. On-...
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

The Circadian System Contributes to Apnea Lengthening across the Night in Obstructive Sleep Apnea
Conclusions:The endogenous circadian system plays an important role in the prolongation of respiratory events across the night, and might provide a novel therapeutic target for modulating sleep apnea.Citation:Butler MP, Smales C, Wu H, Hussain MV, Mohamed YA, Morimoto M, Shea SA. The circadian system contributes to apnea lengthening across the night in obstructive sleep apnea. SLEEP 2015;38(11):1793–1801. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

Negative Expiratory Pressure Technique: An Awake Test to Measure Upper Airway Collapsibility in Adolescents
Conclusions:The negative expiratory pressure (NEP) technique correlates with the hypotonic and activated slope of pressure-flow relationship measurements. The seated position showed the strongest correlation. The NEP technique can be used as an alternative method to evaluate upper airway collapsibility in adolescents.Citation:Carrera HL, Marcus CL, McDonough JM, Morera JC, Huang J, Farre R, Montserrat JM. Negative expiratory pressure technique: an awake test to measure upper airway collapsibility in adolescents. SLEEP 2015;38(11):1783–1791. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

Study of a Novel APAP Algorithm for the Treatment of Obstructive Sleep Apnea in Women
Conclusion:Among premenopausal women a novel female-specific autotitrating algorithm (AfH) is as effective as the standard AutoSet algorithm in controlling obstructive sleep apnea (OSA). The new algorithm may reduce flow limitation more than the standard algorithm and achieve control of OSA at a lower (95th centile) pressure.Citation:McArdle N, King S, Shepherd K, Baker V, Ramanan D, Ketheeswaran S, Bateman P, Wimms A, Armitstead J, Richards G, Hillman D, Eastwood P. Study of a novel APAP algorithm for the treatment of obstructive sleep apnea in women. SLEEP 2015;38(11):1775–1781. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

Sleep Patterns in Adults with a Diagnosis of High-Functioning Autism Spectrum Disorder
Conclusions:These findings support the notion that problems related to sleep, in particular insomnia, continue into adulthood in individuals with high-functioning autism spectrum disorder.Citation:Baker EK, Richdale AL. Sleep patterns in adults with a diagnosis of high-functioning autism spectrum disorder. SLEEP 2015;38(11):1765–1774. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

Nonpharmacological Treatments of Insomnia for Long-Term Painful Conditions: A Systematic Review and Meta-analysis of Patient-Reported Outcomes in Randomized Controlled Trials
Conclusions: Although the body of evidence was small, nonpharmacological sleep interventions may represent a fruitful avenue for optimizing treatment outcomes in patients with chronic pain. Registration: PROSPERO registration: CRD42013004131. Citation: Tang NK, Lereya T, Boulton H, Miller MA, Wolke D, Cappuccio FP. Nonpharmacological treatments of insomnia for long-term painful conditions: a systematic review and meta-analysis of patient-reported outcomes in randomized controlled trials. SLEEP 2015;38(11):1751–1764. (Source: Sleep)
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

Cortical Drive to Breathe during Wakefulness in Patients with Obstructive Sleep Apnea Syndrome
Conclusions:A respiratory-related cortical activity could contribute to the increased neural drive to upper airway and to inspiratory muscles that has previously been described in obstructive sleep apnea, and could therefore contribute to the arousal-dependent compensation of upper airway abnormalities. Whether or not such cortical compensatory mechanisms have cognitive consequences remains to be determined.Citation:Launois C, Attali V, Georges M, Raux M, Morawiec E, Rivals I, Arnulf I, Similowski T. Cortical drive to breathe during wakefulness in patients with obstructive sleep apnea syndrome. SLEEP 2015;38(11):1743–...
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research

The Effects of Sleep Continuity Disruption on Positive Mood and Sleep Architecture in Healthy Adults
Conclusions:To our knowledge, this is the first human experimental study to demonstrate that, despite comparable reductions in total sleep time, partial sleep loss from sleep continuity disruption is more detrimental to positive mood than partial sleep loss from delaying bedtime, even when controlling for concomitant increases in negative mood. With these findings, we provide temporal evidence in support of a putative biologic mechanism (slow wave sleep deficit) that could help explain the strong comorbidity between insomnia and depression.Citation:Finan PH, Quartana PJ, Smith MT. The effects of sleep continuity disruption...
Source: Sleep - October 31, 2015 Category: Sleep Medicine Source Type: research