Sleep Duration and Midday Napping with 5-Year Incidence and Reversion of Metabolic Syndrome in Middle-Aged and Older Chinese
Conclusions:Both longer sleep duration and longer midday napping were potential risk factors for MetS incidence, and concurrently exert adverse effects on MetS reversion.Citation:Yang L, Xu Z, He M, Yang H, Li X, Min X, Zhang C, Xu C, Angileri F, Légaré S, Yuan J, Miao X, Guo H, Yao P, Wu T, Zhang X. Sleep duration and midday napping with 5-year incidence and reversion of metabolic syndrome in middle-aged and older Chinese.SLEEP 2016;39(11):1911–1918. (Source: Sleep)
Source: Sleep - November 1, 2016 Category: Sleep Medicine Source Type: research

Habitual Sleep Duration and All-Cause Mortality in a General Community Sample
Conclusion:Long sleep duration or a shift from long to short sleep duration are independently associated with all-cause mortality.Citation:Aurora RN, Kim JS, Crainiceanu C, O'Hearn D, Punjabi NM. Habitual sleep duration and all-cause mortality in a general community sample.SLEEP 2016;39(11):1903–1909. (Source: Sleep)
Source: Sleep - November 1, 2016 Category: Sleep Medicine Source Type: research

Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice
Conclusions:Even after prolonged normoxic recovery after IH exposures, gut microbiota and circulating endotoxemia remain negatively altered, suggesting that potential benefits of OSA treatment for reversing OSA-induced changes in gut microbiota may either require a longer period or alternative interventions.Citation:Moreno-Indias I, Torres M, Sanchez-Alcoholado L, Cardona F, Almendros I, Gozal D, Montserrat JM, Queipo-Ortuño MI, Farré R. Normoxic recovery mimicking treatment of sleep apnea does not reverse intermittent hypoxia-induced bacterial dysbiosis and low-grade endotoxemia in mice.SLEEP 2016;39(10):189...
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Management and Risk Reduction of Rheumatoid Arthritis in Individuals with Obstructive Sleep Apnea: A Nationwide Population-Based Study in Taiwan
Conclusions:Patients with OSA are associated with higher risk for developing RA, SS, and Behçet disease. OSA management is associated with reduced risk of RA.Citation:Chen WS, Chang YS, Chang CC, Chang DM, Chen YH, Tsai CY, Chen JH. Management and risk reduction of rheumatoid arthritis in individuals with obstructive sleep apnea: a nationwide population-based study in Taiwan.SLEEP 2016;39(10):1883–1890. (Source: Sleep)
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Work-Family Conflict and Employee Sleep: Evidence from IT Workers in the Work, Family and Health Study
Conclusions:Results highlight the unique associations of WTFC/FTWC with employee sleep independent of other work conditions and household and sociodemographic characteristics. Our novel methodological approach demonstrates differential associations of WTFC and FTWC with inconsistency of sleep timing. Given the strong associations between WTFC and poor sleep, future research should focus on reducing WTFC.Citation:Buxton OM, Lee S, Beverly C, Berkman LF, Moen P, Kelly EL, Hammer LB, Almeida DM. Work-family conflict and employee sleep: evidence from IT workers in the Work, Family and Health Study.SLEEP 2016;39(10):1871–...
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium
Conclusions:The significant SNP heritability of sleep duration in children and the suggestive genetic overlap with type 2 diabetes support the search for genetic mechanisms linking sleep duration in children to multiple outcomes in health and disease.Citation:Marinelli M, Pappa I, Bustamante M, Bonilla C, Suarez A, Tiesler CM, Vilor-Tejedor N, Zafarmand MH, Alvarez-Pedrerol M, Andersson S, Bakermans-Kranenburg MJ, Estivill X, Evans DM, Flexeder C, Forns J, Gonzalez JR, Guxens M, Huss A, van IJzendoorn MH, Jaddoe VW, Julvez J, Lahti J, López-Vicente M, Lopez-Espinosa MJ, Manz J, Mileva-Seitz VR, Perola M, Pesonen AK,...
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Genetic Correlation Analysis Suggests Association between Increased Self-Reported Sleep Duration in Adults and Schizophrenia and Type 2 Diabetes
Conclusions:Our results show that increased sample sizes will identify more common variants for self-report sleep duration; however, the heritability tagged is small when compared to other traits and diseases. These results also suggest that those who carry variants that increase risk to type 2 diabetes and schizophrenia are more likely to report longer sleep duration.Citation:Byrne EM, Gehrman PR, Trzaskowski M, Tiemeier H, Pack AI. Genetic correlation analysis suggests association between increased self-reported sleep duration in adults and schizophrenia and type 2 diabetes.SLEEP 2016;39(10):1853–1857. (Source: Sleep)
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Sleep Duration and Neurocognitive Function in the Hispanic Community Health Study/Study of Latinos
Conclusions:Sleep duration had curvilinear inverted U-shaped associations with neurocognitive function, with worse scores among participants with longer sleep duration. These findings may provide a framework to further examine sleep duration in the prevention and treatment of neurocognitive disorders.Citation:Ramos AR, Tarraf W, Daviglus M, Davis S, Gallo LC, Mossavar-Rahmani Y, Penedo FJ, Redline S, Rundek T, Sacco RL, Sotres-Alvarez D, Wright CB, Zee PC, González HM. Sleep duration and neurocognitive function in the Hispanic Community Health Study/Study of Latinos.SLEEP 2016;39(10):1843–1851. (Source: Sleep)
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

A Unified Model of Performance for Predicting the Effects of Sleep and Caffeine
Conclusions:The UMP provides the first comprehensive tool for accurate selection of combinations of sleep schedules and caffeine countermeasure strategies to optimize neurobehavioral performance.Citation:Ramakrishnan S, Wesensten NJ, Kamimori GH, Moon JE, Balkin TJ, Reifman J. A unified model of performance for predicting the effects of sleep and caffeine.SLEEP 2016;39(10):1827–1841. (Source: Sleep)
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Scalp and Source Power Topography in Sleepwalking and Sleep Terrors: A High-Density EEG Study
Conclusions:Overall, results suggest the presence of local sleep differences in the brain of SADs patients during nights without clinical episodes. The persistence of similar topographical changes in local EEG power during REM sleep and wakefulness points to trait-like functional changes that cross the boundaries of NREM sleep. The regions identified by source imaging are consistent with the current neurophysiological understanding of SADs as a disorder caused by local arousals in motor and cingulate cortices. Persistent localized changes in neuronal excitability may predispose affected subjects to clinical episodes.Citati...
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Post Tick-Borne Encephalitis Virus Vaccination Narcolepsy with Cataplexy
Conclusions:Our findings implicate TBE vaccination as a potential additional environmental factor for the development of NC and add additional evidence for an immunological mechanism in the pathogenesis of the disease.Citation:Hidalgo H, Kallweit U, Mathis J, Bassetti CL. Post tick-borne encephalitis virus vaccination narcolepsy with cataplexy.SLEEP 2016;39(10):1811–1814. (Source: Sleep)
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Periodic Limb Movements in Sleep are Associated with Greater Cognitive Decline in Older Men without Dementia
Conclusions:Among older men without dementia, higher PLMS frequency was associated with greater decline in cognition, particularly in executive function.Citation:Leng Y, Blackwell T, Stone KL, Hoang TD, Redline S, Yaffe K. Periodic limb movements in sleep are associated with greater cognitive decline in older men without dementia.SLEEP 2016;39(10):1807–1810. (Source: Sleep)
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Prevalence, Correlates, and Predictors of Insomnia in the US Army prior to Deployment
Conclusions:Insomnia occurs in about one of five service members prior to a military deployment and is associated with a wide array of psychosocial stressors and mental and physical health problems.Citation:Taylor DJ, Pruiksma KE, Hale WJ, Kelly K, Maurer D, Peterson AL, Mintz J, Litz BT, Williamson DE, STRONG STAR Consortium. Prevalence, correlates, and predictors of insomnia in the US Army prior to deployment.SLEEP 2016;39(10):1795–1806. (Source: Sleep)
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Sleep-Wake Differences in Relative Regional Cerebral Metabolic Rate for Glucose among Patients with Insomnia Compared with Good Sleepers
Conclusions:Insomnia was characterized by regional alterations in relative glucose metabolism across NREM sleep and wakefulness. Significant group-by-state interactions in relative rCMRglc suggest that insomnia is associated with impaired disengagement of brain regions involved in cognition (left frontoparietal), self-referential processes (precuneus/posterior cingulate), and affect (left middle frontal, fusiform/lingual gyri) during NREM sleep, or alternatively, to impaired engagement of these regions during wakefulness.Citation:Kay DB, Karim HT, Soehner AM, Hasler BP, Wilckens KA, James JA, Aizenstein HJ, Price JC, Rosar...
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research

Internet-Based Cognitive Behavioral Therapy for Insomnia: A Health Economic Evaluation
Conclusions:Focusing on sleep improvement using iCBT-I may be a cost-effective strategy in occupational health care.Clinical Trials Registration:Title: Online Recovery Training for Better Sleep in Teachers with High Psychological Strain. German Clinical Trial Register (DRKS), URL:https://drks-neu.uniklinik-freiburg.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00004700. Identifier: DRKS00004700.Commentary:A commentary on this article appears in this issue on page 1767.Citation:Thiart H, Ebert DD, Lehr D, Nobis S, Buntrock C, Berking M, Smit F, Riper H. Internet-based cognitive behavioral therapy for inso...
Source: Sleep - October 1, 2016 Category: Sleep Medicine Source Type: research