Collectively these findings demonstrate for the first time that ISS imparts significant lasting disturbances in sleep/wake activity, degeneration of wake-activated LC and orexinergic neurons, and lasting metabolic changes in remaining neurons most consistent with premature senescence. < /p > < /div > < div class="section" > < a name="d7e151" > < !-- named anc..."> Collectively these findings demonstrate for the first time that ISS imparts significant lasting disturbances in sleep/wake activity, degeneration of wake-activated LC and orexinergic neurons, and lasting metabolic changes in remaining neurons most consistent with premature senescence. < /p > < /div > < div class="section" > < a name="d7e151" > < !-- named anc..." /> Collectively these findings demonstrate for the first time that ISS imparts significant lasting disturbances in sleep/wake activity, degeneration of wake-activated LC and orexinergic neurons, and lasting metabolic changes in remaining neurons most consistent with premature senescence. < /p > < /div > < div class="section" > < a name="d7e151" > < !-- named anc..." />

Intermittent Short Sleep Results in Lasting Sleep Wake Disturbances and Degeneration of Locus Coeruleus and Orexinergic Neurons

Conclusions: < /h3 > < p id="d7e149" > Collectively these findings demonstrate for the first time that ISS imparts significant lasting disturbances in sleep/wake activity, degeneration of wake-activated LC and orexinergic neurons, and lasting metabolic changes in remaining neurons most consistent with premature senescence. < /p > < /div > < div class="section" > < a name="d7e151" > < !-- named anchor -- > < /a > < h3 class="section-title" > Citation: < /h3 > < p id="d7e154" > Zhu Y, Fenik P, Zhan G, Somach R, Xin R, Veasey S. Intermittent short sleep results in lasting sleep wake disturbances and degeneration of locus coeruleus and orexinergic neurons. < i > SLEEP < /i > 2016;39(8):1601 & #8211;1611. < /p > < /div > < /div >
Source: Sleep - Category: Sleep Medicine Source Type: research