Role of probiotics in treatment of Congenital Heart Disease and Necrotizing Enterocolitis
This article seeks to review and evaluate the effect of probiotics on congenital heart diseases and NEC prevention in preterm infant (Source: PharmaNutrition)
Source: PharmaNutrition - March 13, 2019 Category: Nutrition Source Type: research
Editorial Board
Publication date: March 2019Source: PharmaNutrition, Volume 7Author(s): (Source: PharmaNutrition)
Source: PharmaNutrition - March 4, 2019 Category: Nutrition Source Type: research
Impact of the inhibition of proteins activities and the chemical aspect of polyphenols-proteins interactions
Publication date: Available online 3 January 2019Source: PharmaNutritionAuthor(s): Nassim Salem Adrar, Khodir Madani, Sabah AdrarAbstractThe good nutritional value and the interesting biological activities of the plant-based nutraceuticals are primarily due to the polyphenols. These latter are among the most important and extensively studied plant secondary metabolites and their interaction with proteins is the subject of considerable researches. This interaction is fundamental to the rational design of functional foods as well as to improve the bioavailability and the biofunctionality of the polyphenols. In this work, we ...
Source: PharmaNutrition - January 4, 2019 Category: Nutrition Source Type: research
Horseradish (Moringa oleifera) seed and leaf inclusive diets modulates activities of enzymes linked with hypertension, and lipid metabolites in high-fat fed rats
This study examined the effects of Horseradish leaves and seeds inclusive diets on angiotensin-I converting enzyme (ACE) and arginase activities and lipid [total cholesterol (TC), triglycerides (TGs), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C)] metabolites in rats fed with high-cholesterol (HC) diet. Animals were divided into seven groups (n = 7) including normal control rats (NC) and untreated hypercholesterolemia rats (HC). Phenolic constituents of the horseradish leaf and seed were determined via high performance liquid chromatography (HPLC-DAD). The result revealed ...
Source: PharmaNutrition - December 27, 2018 Category: Nutrition Source Type: research
Hydrolysable tannins, gallic acid, and ellagic acid in Walnut Reduced 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) Reduction in T-Cells Cultured from the Spleen of Mice
Publication date: Available online 28 November 2018Source: PharmaNutritionAuthor(s): Yui Hamada, Rie Haramiishi, Yuusei Ojima, Yoshiaki Amakura, Morio Yoshimura, Atsushi Sawamoto, Satoshi Okuyama, Yoshiko Furukawa, Mitsunari NakajimaAbstractWalnut is an allergenic food in some populations. Although some allergenic proteins have been identified in walnuts, few small molecule components in the food have been evaluated for their immunomodulatory functions. To examine the immunomodulatory functions, we cultured T-cells from the spleen of mice with small molecule compounds in walnut, measured 3-(4,5-dimethylthiazol-2-yl)-2,5-di...
Source: PharmaNutrition - November 28, 2018 Category: Nutrition Source Type: research
Editorial Board
Publication date: December 2018Source: PharmaNutrition, Volume 6, Issue 4Author(s): (Source: PharmaNutrition)
Source: PharmaNutrition - November 25, 2018 Category: Nutrition Source Type: research
Probiotics for Improving Quality of Life in Ulcerative Colitis: Exploring the Patient Perspective
This study therefore qualitatively explored UC’s impact on QoL from a patient perspective, and evaluated the potential of a multispecies probiotic for impact alleviation. Semi-structured interviews were held with 23 UC patients, who had either opted for a trial period with the multispecies probiotic Ecologic® 825 (n=14) or had not (n=9). The thematic analysis elucidates the broad nature of UC’s impact, identifying 5 core impact domains and effects throughout. Furthermore, as patients’ attitudes towards probiotics were predominantly positive, 57% of users reported positive impact of consumption, and the vast majority...
Source: PharmaNutrition - November 16, 2018 Category: Nutrition Source Type: research
Olive Fruit (Olea Europaea L.): Chemopreventive Effect in the Rat Model of Hepatocellular Carcinoma
Publication date: Available online 24 October 2018Source: PharmaNutritionAuthor(s): Farshad H. Shirazi, Mehrdad Piri, Shima Keshavarz, Saman Gholami, Seyed Hojjat Hosseini, Maryam Noubarani, Sina Andalib, Mohammad Kamalinejad, Hasan Adiban, Mohammad Reza EskandariAbstractPrimary liver cancer or hepatocellular carcinoma (HCC) is an aggressive tumor with poor prognosis. Olea europaea L. commonly called olive contains diverse phytochemical constituents that have preventive effects against different diseases. The purpose of this investigation was to study the chemopreventive effect of aqueous extract of Olea europaea L. (AOE) ...
Source: PharmaNutrition - October 25, 2018 Category: Nutrition Source Type: research
Commensal lactic acid-producing bacteria affect host cellular lipid metabolism through various cellular metabolic pathways: Role of mTOR, FOXO1, and autophagy machinery system
ConclusionLAPB prevent high- fat diet/endotoxin/inflammation-mediated disruption of normal cellular lipid metabolism by inhibiting mTOR/FOXO1/NF-kB activity and enhancing the occurrence of autophagy. This may be a molecular basis by which LAPB enhance intrinsic cellular tolerance against excess calorie consumption and participate in homeostatic regulation of metabolic processes in vivo.Graphical abstract (Source: PharmaNutrition)
Source: PharmaNutrition - October 25, 2018 Category: Nutrition Source Type: research
γ-Oryzanol supplementation modifies the inflammatory and oxidative response in fulminant hepatic failure in mice
Publication date: Available online 12 October 2018Source: PharmaNutritionAuthor(s): Marcelo Gomes de Gomes, Franciele Donato, Leandro Cattelan Souza, André Rossito Goes, Carlos Borges Filho, Lucian Del Fabbro, Matheus Chimelo Bianchini, Waseem Hassan, Silvana Peterini Boeira, Robson Luiz Puntel, Cristiano Ricardo JesseAbstractThe lipopolysaccharide (LPS) and D-galactosamine (D-GalN)-induced hepatotoxicity is a classical model to elucidate the mechanisms and explore potential therapeutic drugs for fulminant hepatic failure (FHF). γ-Oryzanol (γ-ORY) has been showed to possess both antioxidant and anti-inflammatory propert...
Source: PharmaNutrition - October 13, 2018 Category: Nutrition Source Type: research
Economic Potential of Probiotic Supplementation in Institutionalized Elderly with Chronic Constipation
Publication date: Available online 9 October 2018Source: PharmaNutritionAuthor(s): J. Flach, M. Koks, M.B. van der Waal, E. Claassen, O.F.A. LarsenAbstractProbiotics have been suggested as an effective supplementation to conventional treatment regimens for chronic constipation in nursing homes, but the financial impact of the intervention for these institutions remains to be determined. We therefore set out to investigate the economic potential of probiotic supplementation in a nursing home setting with regard to constipation management. We aimed to determine the probiotic lower efficacy limit required to reduce the instit...
Source: PharmaNutrition - October 10, 2018 Category: Nutrition Source Type: research
Mitochondria protecting amino acids: Application against a wide range of mitochondria-linked complications
Publication date: December 2018Source: PharmaNutrition, Volume 6, Issue 4Author(s): Reza Heidari, Vahid Ghanbarinejad, Mohammad Mehdi Ommati, Akram Jamshidzadeh, Hossein NiknahadAbstractMitochondria are cellular power plants which any defect in their proper function might lead to deleterious consequences. Mitochondrial dysfunction has been identified as a pivotal mechanism involved in the pathogenesis of xenobiotics-induced toxicity as well as in the etiology of several diseases. In this context, protecting mitochondria could play a crucial role in the development of therapeutic strategies against a wide range of clinical ...
Source: PharmaNutrition - October 5, 2018 Category: Nutrition Source Type: research
Editorial Board
Publication date: September 2018Source: PharmaNutrition, Volume 6, Issue 3Author(s): (Source: PharmaNutrition)
Source: PharmaNutrition - August 8, 2018 Category: Nutrition Source Type: research
Casein-derived antioxidative peptide prevents oxidative stress-induced dysfunction in osteoblast cells
Publication date: December 2018Source: PharmaNutrition, Volume 6, Issue 4Author(s): Sanusi Bello Mada, Srinu Reddi, Naveen Kumar, Rishika Vij, Radha Yadav, Suman Kapila, Rajeev KapilaAbstractOxidative stress has been linked to osteoblast cells dysfunction and plays a crucial role in the pathogenesis of postmenopausal osteoporosis. The present study was designed to investigate the effects casein-derived antioxidative peptide VLPVPQK (PEP) against hydrogen peroxide (H2O2)-induced dysfunction and oxidative damage in osteoblast cells. The present data demonstrated that treatment of osteoblast cells with PEP increases cell viab...
Source: PharmaNutrition - July 21, 2018 Category: Nutrition Source Type: research
Jaboticaba peel extract decrease autophagy in white adipose tissue and prevents metabolic disorders in mice fed with a high-fat diet
Publication date: December 2018Source: PharmaNutrition, Volume 6, Issue 4Author(s): Andressa Mara Baseggio, Carla Evelyn Coimbra Nuñez, Nathalia Romanelli Vicente Dragano, Celina Almeida Lamas, Patrícia Aparecida de Campos Braga, Sabrina Alves Lenquiste, Felix Guillermo Reyes Reyes, Valéria Helena Alves Cagnon, Mário Roberto Maróstica JúniorAbstractThe increase in autophagy markers in the white adipose tissue is associated with adipocyte hypertrophy and obesity physiopathology. The jaboticaba peel is rich in bioactive compounds as polyphenols, which have been demonstrating anti-oxidant and inflammatory effects, and p...
Source: PharmaNutrition - July 19, 2018 Category: Nutrition Source Type: research
