Better prepare for the next one. Lifestyle lessons from the COVID-19 pandemic
Publication date: Available online 6 May 2020Source: PharmaNutritionAuthor(s): Francesco Galli, Guillermo Reglero, Desirée Bartolini, Francesco Visioli (Source: PharmaNutrition)
Source: PharmaNutrition - May 7, 2020 Category: Nutrition Source Type: research

Tinospora cordifolia attenuates high fat diet-induced obesity and associated hepatic and renal dysfunctions in rats
Publication date: Available online 26 April 2020Source: PharmaNutritionAuthor(s): Harpal Singh, Ashwani K. Sharma, Muskan Gupta, Amrit Pal Singh, Gurcharan Kaur (Source: PharmaNutrition)
Source: PharmaNutrition - April 28, 2020 Category: Nutrition Source Type: research

Pharmacological targeting of neurotensin response by diet-derived EGCG in macrophage-differentiated HL-60 promyelocytic leukemia cells
Publication date: Available online 23 April 2020Source: PharmaNutritionAuthor(s): Tiziana Dao, Syim Salahuddin, Cyndia Charfi, Audrey-Ann Sicard, Mohammad-Ali Jenabian, Borhane Annabi (Source: PharmaNutrition)
Source: PharmaNutrition - April 24, 2020 Category: Nutrition Source Type: research

Intravenous Vitamin C for reduction of cytokines storm in Acute Respiratory Distress Syndrome
Publication date: Available online 21 April 2020Source: PharmaNutritionAuthor(s): Alberto Boretti, Bimal Krishna Banik (Source: PharmaNutrition)
Source: PharmaNutrition - April 22, 2020 Category: Nutrition Source Type: research

A polyphenol rich sugarcane extract as a modulator for inflammation and neurological disorders
Publication date: Available online 12 March 2020Source: PharmaNutritionAuthor(s): Jin Ji, Matthew Flavel, Xin Yang, Oliver C.Y. Chen, Luke Downey, Con Stough, Barry Kitchen (Source: PharmaNutrition)
Source: PharmaNutrition - March 14, 2020 Category: Nutrition Source Type: research

Inter-individual differences in pharmacokinetics of vitamin B6: a possible explanation of different sensitivity to its neuropathic effects
Publication date: Available online 10 March 2020Source: PharmaNutritionAuthor(s): Misha F Vrolijk, Geja J Hageman, Sonja van de Koppel, Florence van Hunsel, Aalt Bast (Source: PharmaNutrition)
Source: PharmaNutrition - March 12, 2020 Category: Nutrition Source Type: research

Fish protein hydrolysate supplementation improves vascular reactivity in individuals at high risk factors for cardiovascular disease: a pilot study
Publication date: Available online 3 March 2020Source: PharmaNutritionAuthor(s): Gustavo Vieira de Oliveira, Mônica Volino-Souza, Elisaldo Mendes Cordeiro, Thiago Silveira Alvares (Source: PharmaNutrition)
Source: PharmaNutrition - March 3, 2020 Category: Nutrition Source Type: research

Editorial Board
Publication date: March 2020Source: PharmaNutrition, Volume 11Author(s): (Source: PharmaNutrition)
Source: PharmaNutrition - March 2, 2020 Category: Nutrition Source Type: research

Betaine supplementation mitigates intestinal damage and decreases serum bacterial endotoxin in cirrhotic rats
Publication date: June 2020Source: PharmaNutrition, Volume 12Author(s): Mohammad Mehdi Ommati, Omid Farshad, Khadijeh Mousavi, Akram Jamshidzadeh, Mohammadreza Azmoon, Sirus Heidari, Negar Azarpira, Hossein Niknahad, Reza HeidariAbstractGut barrier dysfunction and bacterial endotoxin (Lipopolysaccharide; LPS) translocation to the systemic circulation are prominent clinical challenges in cirrhotic patients. Several investigations mentioned the role of oxidative stress in this complication. In the current study, the effects of BET (0.5 and 1 % w: v, gavage) on biomarkers of oxidative stress, tissue histopathological alterati...
Source: PharmaNutrition - February 12, 2020 Category: Nutrition Source Type: research

Prebiotics may alter bile salt hydrolase activity: Possible implications for cholesterol metabolism
In this study the ability of probiotic Lactobacilli species to deconjugate bile salts in the presence of various prebiotics was determined by measuring cholic acid release. The kinetic properties of BSH was assessed to determine the impact the prebiotics on bile salt deconjugation. When L. acidophilus NCTC 1723 was incubated with inulin (1%) there was a significant (p < 0.01) increase in cholic acid release by 0.16 nmol/min. Lactulose and lactobionic acid at 1% decreased cholic acid release to 0.2 nmol/min and 0.06 nmol/min respectively. In the presence of the pure BSH, inulin and lactulose (0-6%) altered Km ...
Source: PharmaNutrition - February 11, 2020 Category: Nutrition Source Type: research

Caffeine but not acetaminophen increases 4-km cycling time-trial performance
Publication date: Available online 25 January 2020Source: PharmaNutritionAuthor(s): F. Tomazini, A.C. Santos-Mariano, V.A. Andrade-Souza, V.C. Sebben, C.A. De Maria, D.B. Coelho, R. Bertuzzi, M.D. Silva-Cavalcante, A.E. Lima-SilvaAbstractAcetaminophen has been combined with caffeine for therapeutic purpose, but the effect of co-ingestion of acetaminophen and caffeine on exercise performance has not been investigated. To determine the effect of isolated and combined ingestion of caffeine and acetaminophen on performance during a 4-km cycling time-trial (4 T T). Eleven men, completed a 4 T T one hour after the ingest...
Source: PharmaNutrition - January 25, 2020 Category: Nutrition Source Type: research

Honey and glycemic control: a systematic review
Publication date: Available online 23 January 2020Source: PharmaNutritionAuthor(s): Maryam Zamanian, Fatemeh Azizi-SoleimanAbstractHoney has long been reported to have curative effects for a number of diseases. The present review aims to provide the most recent findings regarding the potential role of honey in the management of glycemia. Eight studies met the inclusion criteria and were entered in the systematic review. Blood glucose or HbA1c was significantly reduced after consumption of honey in seven studies. However, blood glucose or HbA1C did not differ significantly in two studies, and significantly increased in two ...
Source: PharmaNutrition - January 24, 2020 Category: Nutrition Source Type: research

Betaine supplementation mitigates intestinal barrier disintegrity and bacterial endotoxin translocation in cirrhotic rats
Publication date: Available online 16 January 2020Source: PharmaNutritionAuthor(s): Mohammad Mehdi Ommati, Omid Farshad, Khadijeh Mousavi, Akram Jamshidzadeh, Mohammadreza Azmoon, Sirus Heidari, Negar Azarpira, Hossein Niknahad, Reza HeidariAbstractGut barrier disintegrity and high serum bacterial endotoxin (Lipopolysaccharide; LPS) level is a prominent clinical challenge in cirrhotic patients. Several investigations mentioned the pivotal role of oxidative stress in this complication. Betaine (BET) is widely investigated for its physio/pharmacological properties. It has been found that BET mitigates oxidative stress in dif...
Source: PharmaNutrition - January 16, 2020 Category: Nutrition Source Type: research

Blood brain barrier inflammation and potential therapeutic role of phytochemicals
Publication date: Available online 9 January 2020Source: PharmaNutritionAuthor(s): Menizibeya O. WelcomeAbstractThe blood brain barrier (BBB) is a neurovascular unit that protects the brain from peripheral insults, and plays a critical role in regulating cerebral homeostasis. Data have consistently demonstrated BBB inflammation as the hallmark of several central nervous system (CNS) diseases. Unfortunately, the mechanisms that trigger BBB inflammation in different CNS disorders are not fully understood. In particular, it is not known how the BBB changes from a protective barrier to a pathological one that underlies disrupt...
Source: PharmaNutrition - January 10, 2020 Category: Nutrition Source Type: research

Neuroinflammation in CNS diseases: molecular mechanisms and the therapeutic potential of plant derived bioactive molecules
Publication date: Available online 9 January 2020Source: PharmaNutritionAuthor(s): Menizibeya O. WelcomeAbstractOver the past decades, evidences have consistently shown that neuroinflammation is a critical underlying process in a range of CNS diseases, including neurodegenerative disorders, depression, sleep disorders, and stroke. Thus prevention of neuroinflammation represents one of the most important goals in the treatment of these disorders. Unfortunately, the mechanisms of neuroinflammation in different CNS disorders are not fully understood. Here, I review recent literature data on the mechanisms of neuroinflammation...
Source: PharmaNutrition - January 10, 2020 Category: Nutrition Source Type: research