European General Practitioners perceptions on probiotics: Results of a multinational survey
Publication date: Available online 9 January 2020Source: PharmaNutritionAuthor(s): A.M. van der Geest, J. Flach, E. Claassen, A.W. Sijlmans, L.H.M. van de Burgwal, O.F.A. LarsenAbstractPublic opinion and consumer adoption of probiotics is influenced by the perception and recommendations of General Practitioners (GPs), but the perceptions and recommendations of European GPs currently appear to be underreported. This paper therefore relates the perceptions of European GPs towards probiotics with their recommendations. Standardized telephonic interviews were conducted with 1318 GPs to assess current perceptions. Fisher’s ex...
Source: PharmaNutrition - January 10, 2020 Category: Nutrition Source Type: research
Protective effects of nicotinamide mononucleotide against oxidative stress-induced PC12 cell death via mitochondrial enhancement
In this study, we hypothesized that NMN attenuates oxidative stress-induced cell damage via sirtuin activation and increased numbers of mitochondria. To investigate whether NMN can protect neuronal cells from oxidative stress via the enhancement of mitochondrial function, we used PC12 cells treated with 6-hydroxydopamine (6-OHDA) or hydrogen peroxide (H2O2) as oxidative stress models. With regard to cytoprotective effects, pretreatment with NMN significantly reduced cell death induced by these stressors. These protective effects were attenuated by the sirtuin inhibitor, sirtinol, and knock-down of the peroxisome proliferat...
Source: PharmaNutrition - December 8, 2019 Category: Nutrition Source Type: research
Editorial Board
Publication date: December 2019Source: PharmaNutrition, Volume 10Author(s): (Source: PharmaNutrition)
Source: PharmaNutrition - November 23, 2019 Category: Nutrition Source Type: research
Natural sources, dopaminergic and non-dopaminergic agents for therapeutic assessment of Parkinsonism in rat model
Publication date: Available online 5 November 2019Source: PharmaNutritionAuthor(s): Manal A. Hamed, Asmaa F. Aboul Naser, Wessam M. Aziz, Faten M. Ibrahim, Sanaa A. Ali, Nagy S. El-Rigal, Wagdy K.B. KhalilAbstractParkinson’s disease (PD) is a chronic neurodegenerative disorder affecting elderly people. The aim of this study is analyze the efficacy of dopaminergic and non- dopaminergic agents, natural sources, in the treatment of rotenone-induced PD in rats. Rotenone-induced PD rats recorded severe alternation in neurotransmitters level, oxidative stress markers, energetic biomarkers, inflammatory mediator, apoptotic inde...
Source: PharmaNutrition - November 7, 2019 Category: Nutrition Source Type: research
Anti-arthritic effect of leafs of Cardiospermum halicacabum juice in patients with rheumatoid arthritis – a case report
Publication date: Available online 28 September 2019Source: PharmaNutritionAuthor(s): R. Arthi, Maheshkumar Kuppusamy (Source: PharmaNutrition)
Source: PharmaNutrition - September 29, 2019 Category: Nutrition Source Type: research
Supplementation with gamma oryzanol ameliorates CCl4-induced hepatic fibrosis in mice
This study revealed that γ-ORY supplementation prevented all alterations CCl4-induced. Thus, the protective effect of γ-ORY supplementation in hepatic fibrosis was trough antioxidant, anti-inflammatory and antiapoptotic activities.Graphical abstract (Source: PharmaNutrition)
Source: PharmaNutrition - September 10, 2019 Category: Nutrition Source Type: research
Editorial Board
Publication date: September 2019Source: PharmaNutrition, Volume 9Author(s): (Source: PharmaNutrition)
Source: PharmaNutrition - September 4, 2019 Category: Nutrition Source Type: research
Modeling of the luminal butyrate concentration to design an oral formulation capable of achieving a pharmaceutical response
Publication date: Available online 31 August 2019Source: PharmaNutritionAuthor(s): Sandra Gabriële Patricia Johanna Korsten, Evelien Alida Wilhelmina Smits, Johan Garssen, Herman VromansAbstractButyrate concentrations required for a direct effect on intestinal epithelial cells lie between 2-5 mM. In order for butyrate to affect the small intestine the local pharmacokinetics need to be understood.We used a mathematical approach to model the luminal butyrate concentration after oral administration of an immediate release formulation or a sustained release formulation to humans. This model was used to design an oral formulat...
Source: PharmaNutrition - September 2, 2019 Category: Nutrition Source Type: research
Anti-inflammatory effect of resin fraction of cardamom (Elettaria cardamomum) in carrageenan-induced rat paw edema
Publication date: Available online 19 August 2019Source: PharmaNutritionAuthor(s): Shantaram Arpitha, Krishnapura Srinivasan, Halagur B. SowbhagyaGraphical abstractAbstractVolatile and non-volatile fractions of cardamom (Elettaria cardamomum) seeds were evaluated for anti-inflammatory influence in paw edema-induced Wistar rats. Groups of rats were orally administered with cardamom oil, cardamom resin, and standard compounds of the volatile cardamom oil fraction as a single dose. Paw inflammation was measured at hourly intervals for 6 hour post-carrageenan administration (i.p.). In another set, groups of rats were maintai...
Source: PharmaNutrition - August 19, 2019 Category: Nutrition Source Type: research
Giving probiotics to your children for gastrointestinal problems: In the light of scientific findings
Publication date: Available online 14 August 2019Source: PharmaNutritionAuthor(s): Parisa Rahmani, Alireza Moradzadeh, Fatemeh FarahmandAbstractProbiotics have become increasingly common within the past few years, owing to their benefits on human health. These are the strains of bacteria and yeast that are administered in the form of food products and supplements to provide lost-health benefits. They can also ameliorate symptoms of numerous diseases and provide protective effects against various pathologies. This review highlights some of the most frequent gastrointestinal problems in children and the therapeutic and preve...
Source: PharmaNutrition - August 15, 2019 Category: Nutrition Source Type: research
Non-digestible oligosaccharides partially prevent the development of LPS-induced lung emphysema in mice
Publication date: Available online 5 August 2019Source: PharmaNutritionAuthor(s): Hamed Janbazacyabar, Jeroen van Bergenhenegouwen, Kim A.T. Verheijden, Thea Leusink-Muis, Ardy van Helvoort, Johan Garssen, Gert Folkerts, Saskia BraberAbstractChronic obstructive pulmonary disease (COPD), a progressive inflammatory disorder, is also known as a systemic inflammatory disease, in which the gut-lung interaction plays an important role. The use of non-digestible oligosaccharides (NDOs) has gained attention in airway diseases due to their systemic effects on inflammatory markers. Here, the preventive effects of specific non-digest...
Source: PharmaNutrition - August 6, 2019 Category: Nutrition Source Type: research
Omega 3-metabolism, absorption, bioavailability and health benefits–A review
Publication date: December 2019Source: PharmaNutrition, Volume 10Author(s): Sneh Punia, Kawaljit Singh Sandhu, Anil Kumar Siroha, Sanju Bala DhullAbstractFor maintaining human health and preventing diseases, interest has been started to develop towards consumption of essential fatty acids. It is positively correlated that consumption of EFA and prevention of heart disease, hypertension, inflammation, cancer prevention, neurological disorders etc. α-Linolenic acid (ALA) also known as omega-3 is an EFA found in plant foods. On consumption, ALA serves as substrate for the synthesis of EPA and DHA, which play a central role i...
Source: PharmaNutrition - August 1, 2019 Category: Nutrition Source Type: research
Omega 3-Metabolism, Absorption, Bioavailability and health benefits- A review
Publication date: Available online 27 July 2019Source: PharmaNutritionAuthor(s): Sneh Punia, Kawaljit Singh Sandhu, Anil Kumar Siroha, Sanju Bala DhullAbstractFor maintaining human health and preventing diseases, interest has been started to develop towards consumption of essential fatty acids. It is positively correlated that consumption of EFA and prevention of heart disease, hypertension, inflammation, cancer prevention, neurological disorders etc. α-Linolenic acid (ALA) also known as omega-3 is an EFA found in plant foods. On consumption, ALA serves as substrate for the synthesis of EPA and DHA, which play a central r...
Source: PharmaNutrition - July 29, 2019 Category: Nutrition Source Type: research
Is food involvement in purchasing decisions always low? A consumer study from Germany
Publication date: September 2019Source: PharmaNutrition, Volume 9Author(s): Carolin Kamrath, Sukhada Bidkar, Stefanie BröringAbstractConsumer demand for health-enhancing food is increasing over the last decade. However, in the European Union, the definition of food is rather broad, i.e. both ordinary food products and dietary supplements are regarded as food, although their presentation format and functionalities considerably differ. This might influence consumers’ involvement in purchasing decisions of dietary supplements compared to ordinary food products. To this end, we explore consumers’ involvement in dietary su...
Source: PharmaNutrition - July 10, 2019 Category: Nutrition Source Type: research
Taurine enhances skeletal muscle mitochondrial function in a rat model of resistance training
Publication date: Available online 5 July 2019Source: PharmaNutritionAuthor(s): Mohammad Mehdi Ommati, Omid Farshad, Akram Jamshidzadeh, Reza HeidariAbstractTaurine (β-amino sulfonic acid; TAU) is the most abundant amino acid in the human body. Recently, the positive effects of TAU on cellular mitochondria has been considered as an interesting mechanism for its beneficial effects. On the other hand, skeletal muscle disorders are debilitating complications, which could affect patients’ quality of life. Moreover, increasing muscle performance and stamina without violating standard rules are of particular interest in athle...
Source: PharmaNutrition - July 7, 2019 Category: Nutrition Source Type: research
