The immune system, the microbiome, and nutrition: Therapeutic linkage
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): H. Rasmussen , A. Keshavarzian , A. Landay (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Role of pharma-nutrition in management and treatment of metabolic syndrome
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): J. Henry (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Essential fatty acids and cardioprotection: New insights
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): F. Visioli (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
The healthy side of taste: Gustatory receptors as drug targets
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): G. Appendino (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Molecular targets of cancer cachexia: Opportunities for pharmanutritional approach
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): M. Sharma (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Non-pharmacological strategies to enhance the efficacy of anti-tumour therapies
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): A. Laviano (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
The antioxidant flavonoid monoHER provides efficient protection and induces the innate Nrf2 mediated adaptation in endothelial cells subjected to oxidative stress
In this study the effect of monoHER on the oxidative stress as well as the adaptive response was investigated. It was found that monoHER protected against oxidative stress caused in HUVECs by H2O2, while monoHER did not prevent the induction of the adaptive response, including the nuclear translocation of Nrf2 as well as the upregulation of HO-1 gene expression. Remarkably, monoHER added to HUVECs which were not subjected to oxidative stress did not cause an adaptive response. The concept that emerges is that by scavenging ROS, the oxidized monoHER formed channels the reactivity selectively to thiol groups. Oxidized monoHE...
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Evaluation of micronutrients supplementation for correction of stunting: A preclinical study
This study related pharmaceutical formulation techniques with correction of retarded linear growth arising from poor nutritional status through a preclinical study. In our previous work, we formulated micronutrients supplementation as a sprinkle powder dosage form. Results of the physicopharmaceutical tests (i.e., uniformity of weight, angle of repose, tapped and bulk density, Hausner’s ratio, and Carr’s index) were acceptable values. Results obtained in this study showed that the best selected supplement formula (F5) was stable physically and chemically during storage period (40 °C and 75% RH) for 12 weeks. The in ...
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Cannflavins from hemp sprouts, a novel cannabinoid-free hemp food product, target microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): Oliver Werz , Julia Seegers , Anja Maria Schaible , Christina Weinigel , Dagmar Barz , Andreas Koeberle , Gianna Allegrone , Federica Pollastro , Lorenzo Zampieri , Gianpaolo Grassi , Giovanni Appendino Hemp seeds are of great nutritional value, containing all essential amino acids and fatty acids in sufficient amount and ratio to meet the dietary human demand. Hemp seeds do not contain cannabinoids, and because of their high contents of ω-3 fatty acids, are enjoying a growing popularity as a super-food to beneficially affect c...
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Cover story: Towards a new paradigm in nutraceutical research
Publication date: July 2014 Source:PharmaNutrition, Volume 2, Issue 3 Author(s): Francesco Visioli (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Preventive effect of Rubus fruticosus on learning and memory impairment in an experimental model of diabetic neuropathy in male rats
In this study we evaluated the effect of R. fruticosus (RF) extract against memory dysfunction on streptozocin (STZ) induced diabetic neuropathy. Diabetes was induced by a single injection of STZ (60mg/kg i.p). Treatments were begun at the onset of hyperglycemia, followed by treatment with the RF extract (100, 200 and 400mg/kg p.o) for 4 weeks. Cognitive functions were evaluated using passive avoidance learning (PAL) task. Retention test was carried out 24h after training. At the end of experiment, animals were weighted and blood samples were taken for plasma glucose measurement. Diabetes caused impairment in acquisition a...
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
β-Cryptoxanthin rich paprika extract prevents ovariectomy induced bone loss in Wistar rats
Publication date: October 2014 Source:PharmaNutrition, Volume 2, Issue 4 Author(s): Rahul S. Chaudhari , Vikas B. Mankumare , J. Shankaranarayanan , Jayant V. Deshpande , T.K. Sunilkumar , Sadhana Sathaye Recent studies show that high intake of carotenoids is helpful in preventing bone loss in post-menopausal women. Carotenoids like β-cryptoxanthin increases calcium and phosphorus deposition in cultured osteoblasts. β-Cryptoxanthin is also reported to have anabolic property in cultured osteoblast cells. It can also inhibit bone resorption process. Paprika and its dietary products are rich in carotenoids like β...
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Eight-week consumption of milk enriched with omega 3 fatty acids raises their blood concentrations yet does not affect lipids and cardiovascular disease risk factors in adult healthy volunteers
In conclusion, daily consumption of 500mL of 1% fat milk enriched with omega-3 FA for eight weeks leads to higher blood levels of EPA and DHA, confirming that milk is an optimal matrix for the provision of important micronutrients. Graphical abstract (Source: PharmaNutrition)
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
Consumption of dietary health supplements among hospitalized patients at an acute tertiary Hospital
This study aims to characterize patients who use DHS, to evaluate the association between DHS use and socio-demographic, lifestyle and dietary habits; and to investigate whether users report DHS use to healthcare professionals (HCPs). Patients admitted to the medical wards, with age ≥21 years, medically stable, cognitively intact and conversant in English, Mandarin or Malay language were interviewed by a dietitian. Of the 100 patients surveyed, up to 42% were DHS users. They tend to be non-smokers (98%) (p =0.02) with higher daily fruit intake of at least two servings (31%) (p =0.02), daily milk intake of at least one cu...
Source: PharmaNutrition - October 12, 2014 Category: Nutrition Source Type: research
