Probiotics for Improving Quality of Life in Ulcerative Colitis: Exploring the Patient Perspective

This study therefore qualitatively explored UC’s impact on QoL from a patient perspective, and evaluated the potential of a multispecies probiotic for impact alleviation. Semi-structured interviews were held with 23 UC patients, who had either opted for a trial period with the multispecies probiotic Ecologic® 825 (n=14) or had not (n=9). The thematic analysis elucidates the broad nature of UC’s impact, identifying 5 core impact domains and effects throughout. Furthermore, as patients’ attitudes towards probiotics were predominantly positive, 57% of users reported positive impact of consumption, and the vast majority of these deemed this as (highly) relevant for improving QoL, the findings favor probiotic supplementation and warrant further clinical evaluation. In this regard, defecation frequency and stool texture seem promising outcome parameters for being most often reported.Graphical abstract
Source: PharmaNutrition - Category: Nutrition Source Type: research