Postepy higieny i medycyny doswiadczalnej This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Postepy Hig Med Dosw 2015; 69:1130-1139 "The diagnosis of latent tuberculosis infection in children in XXI century. Is tuberculin skin test still up to date?"
Tuberculosis morbidity rates in Poland have been gradually decreasing. Nevertheless, there are approximately 8 thousand cases being registered annually, which includes almost 3 thousand massively infectious patients. In the last 3 years, around 100 cases/year have been reported among children below 14 years of age. Infection with Mycobacterium tuberculosis should be considered in all patients who present symptoms suggesting tuberculosis, have had recent contact with a person suffering from lung tuberculosis or are planned to undergo an immunosuppressive treatment. HIV infected patients are also supposed to have screening t...
Source: Postepy higieny i medycyny doswiadczalnej - December 22, 2015 Category: Research Tags: Review article Source Type: research

Postepy Hig Med Dosw 2015; 69:1114-1129 "The role of medicaments, exosomes and miRNA molecules in modulation of macrophage immune activity"
Macrophages play an important role in innate immunity, in induction and orchestration of acquired immune response as well as in the maintenance of tissue homeostasis. Macrophages as antigen presenting cells induce or inhibit the development of immune response and as effector cells play an important role in innate immunity to infectious agents and in delayed--type hypersensitivity as well. Thus, either up- or down-regulation of their activity leads to the impairment of different biological processes. This often results in the development of immunological diseases or inflammatory response associated with metabolic, cardiovas...
Source: Postepy higieny i medycyny doswiadczalnej - December 22, 2015 Category: Research Tags: Review article Source Type: research

Postepy Hig Med Dosw 2015; 69:1107-1113 "The involvement of galectin-3 in heart failure"
Hart failure (HF) accounts for numerous serious problems: medical, social and financial. HF affects 2-3% adult population and its frequency increases with age. Despite advances in laboratory diagnostics of HR the use of biochemical markers remains limited. Currently, only natriuretic peptides, especially type B natriuretic peptides (BNP) and N-terminal fragment of pro-BNP (NT-proBNP) have been fully approved biomarkers employed in diagnosing HF. The concentration of those peptides fluctuates and largely depends on age, gender, renal function, day/night rhythm and volemia which reflects hemodynamic state rather than hart ab...
Source: Postepy higieny i medycyny doswiadczalnej - December 22, 2015 Category: Research Tags: Review article Source Type: research

Postepy Hig Med Dosw 2015; 69:1096-1106 "The role of thiamine in neurodegenerative diseases"
This article presents the current state of knowledge as regards the effects of thiamine exerted through this vitamin in a number of diseases such as Parkinson’s disease, Alzheimer’s disease, Wernicke’s encephalopathy or Wernicke-Korsakoff syndrome and Huntington’s disease. (Source: Postepy higieny i medycyny doswiadczalnej)
Source: Postepy higieny i medycyny doswiadczalnej - December 22, 2015 Category: Research Tags: Review article Source Type: research

Postepy Hig Med Dosw 2015; 69:1087-1095 "Treatment and prophylaxis of influenza and the problem of resistance to neuraminidase inhibitors"
Influenza virus neuraminidase inhibitors (NAIs), including oseltamivir, zanamivir and peramivir, are important antivirals for the treatment and prophylaxis of influenza. Increasing use of NAIs brings into focus the risk of drug resistance. The problem of resistance is of high clinical and epidemiological importance. There are generally three levels of antiviral resistance according to the way that resistance can be detected or inferred: genotypic, phenotypic and clinical resistance. Recently the problem of resistance to NAIs, although still rare (<2% of influenza isolates), has been rising. It should be underlined that ...
Source: Postepy higieny i medycyny doswiadczalnej - December 22, 2015 Category: Research Tags: Review article Source Type: research