Screening of some plant materials used in South-West Algerian traditional medicine for their antibacterial activity
The initial introduction of new medicinal agents into the health care system sometimes, requires information beyond that is recorded in libraries relying instead, on reports available through traditions and healers within a society. This paper explored the antibacterial activity of aqueous and hydromethanolic extracts of nine folkloric medicinal plant from Bechar region (southwest Algeria) namely:A. nardus, A. schoenanthus, G. vulgaris,two species of H. scoparia green& red, P. laevigata, R. tripartita, T. gallica andT. nudatum, frequently used in the local traditional medicine. The antibacterial activity of different e...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Fatehi Naima Source Type: research

Phytochemical screening and In-vitro antioxidant activity of < em > Centella asiatica < /em > extracts
Centella asiatica also known asmandukparnior Indian pennywort orjalbrahmi, which has been used as a medicine in the Ayurveda from ancient times and mentioned in many classical texts of Ayurveda.Centella asiatica has long been used to improve memory and cognitive function.The study aimed to identify the phytochemicals present in different solvent extracts ofCentella asiatica(i.e. PECA- Petroleum ether extract ofC. asiatica,CCA- Chloroform extract ofC. asiatica,EACA- Ethyl acetate extract ofC. asiatica, ECA- Ethanolic extract ofC. asiatica,HACA- Hydro-alcoholic extract ofC. asiatica)and evaluate the respective in-vitro antio...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Mukesh Kumar Yadav Source Type: research

Antitesticular activities of different solvent fractions from hydro-methanol (2:3) extract of < em > Cuminum cyminum < /em > in albino rat: A Comparative analysis
Currently available contraceptives are associated with adverse effects. So, search on safer agents in this purpose is one of the priority areas of WHO. Our previous study showed a significant antifertility effect of hydro-methanol extract ofCuminum cyminum Linn (Umbelliferae) in male albino rat. The main objective of this work isto search outthe potentfraction of hydro-methanol extract of seed ofCuminum cyminum in adult male albino rat for the development of herbal male contraceptive to reduce the bio-burden of phytomolecules. The n-hexane, chloroform, ethyl acetate, and n-butanol fractions of the hydro-methanol (2:3) extr...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Bhabani Prasad Pakhira Source Type: research

Triterpenoids with Cytotoxic Potential from the Leaves of < em > Tridax procumbens < /em > L.
The anticancer activity of crude extracts of the leaves ofTridax procumbens,against two breast cancer cell lines-MCF-7 (benign) and MDA-MB-231 (metastatic) were investigated and an attempt was made to identify the anticancer principle. The extracts with methanol (TPM), ethanol (TPE) and chloroform (TPC) as solvents were screened for cytotoxicity by MTT assay against MCF-7 cells. The effective extract was further evaluated on MDA-MB-231 cells. Among the three extracts, TPC was effective at an IC50 value of 136 µg/ml and 129 µg/ml on MCF-7 and MDA-MB-231 cells respectively. Phytochemical analysis of the extract showed the ...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Vaishali Rai Source Type: research

Evaluation of free radical scavenging activity of leaf of < em > Hypericum mysorense < /em > Heyne
Hypericumis a well-known plant genus in herbal medicine.Hypericum mysorense is well known in folklore medicine for its varied therapeutic potential. Thein vitroantioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extract of leaf ofHypericum mysorensehave been tested using various antioxidant model systems viz; DPPH, hydroxyl, superoxide, ABTS and reducing power. The scavenging effect increases with the concentration of standard and samples. Among the solvent tested, ethanol extract exhibited highest DPPH (116.33% inhibition), hydroxyl (101.84%), superoxide (116.09%) and ABTS (119.22%) radic...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Sornalakshmi V Source Type: research

< em > In vitro < /em > antioxidant activities of stem bark, leaves and callus extracts from < em > Amoora rohituka < /em >
AbstractThe present work examined thein vitro antioxidant activity of sequentially extracted, solvent extracts (Petroleum ether, chloroform and Methanol) of stem bark, leaves and callus fromAmoora rohituka. The antioxidative capacity of the extracts were examined by using DPPH (1,1-diphenyl,2-picryl hydrazyl), ABTS (2,2 ’-azinobis-3-ethyl-benzothiozoline-6-sulphonic acid) and NOS (Nitric oxide scavenging) assays by using Gallic acid as standard control. Among the tested extracts, methanol extract of stem bark showed better antioxidative capacity. The total antioxidant activity was expressed as µg equivalent of G allic a...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Kanthesh M Basalingappa Source Type: research

Phytochemical analysis, Antimicrobial, insecticidal and antiradical activity of < em > Hydnocarpus pentandra < /em > (Buch.-Ham.) Oken
Conclusions: The plant is shown to be an important source of bioactive agents. The observed bioactivities could be attributed to the phytochemicals present in the leaf extract. Further studies on characterization and bioactivity determination of isolated components from leaf extract are to be carried out. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Prashith Kekuda TR Source Type: research

Biological activities and phytochemical screening of < em > Elaeodendron croceum < /em > (Thunb.) DC. Leaves and Stem barks Extracts
Conclusion: These findings support the folkloric usage ofElaeodendron croceum and indicates that it can be used to manage diseases caused by the tested organisms. The presence of alkaloids, flavonoids, total phenols and proanthocyanidins, previously suggested to have antioxidant, anti-inflammatory and antibacterial activity indicate thatE. croceum is a potential source of anti-inflammatory, free radical scavenging and antimicrobial agents. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Samuel Wale Odeyemi Source Type: research

Comparative phytochemical and antioxidant profile of crude seed powder, aqueous and methanolic seed extracts of Buchholzia coriacea
This study was designed to elucidate comparative phytochemical and antioxidant properties of crude seed powder, aqueous and methanolic seed extracts ofBuchholzia coriacea. The results showed that crude seed powder had the highest alkaloid and phenol content of 3.98 ± 0.00% and 0.92 ± 0.00%, while aqueous extract had the least alkaloid and phenol content of 1.00 ± 0.00% and 0.12 ± 0.00% respectively. Methanolic extracts had the highest phytochemical components among the three extracts with flavonoids (12.03 ± 0.0), saponins (1.99 ± 0.01), terpenoids (2.00 ± 0.00), tannin (0.10 ± 0.00) and phytate (2.02 ± 0.01) comp...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Godwin C Ugwu Source Type: research

< em > Glinus oppositifolius < /em > (L.) Aug. DC.: A Repository of Medicinal Potentiality
Plants have been used in the treatment of human diseases since centuries. Due to their medicinal values, more than 80% of the modern world population still rely on plants as their primary source of medicines. Traditional plant-based medicines are widespread in Asian countries like the Indian subcontinent, Bangladesh, China, Japan, Pakistan, Indonesia, Myanmar, and in the continent of Africa. Nowadays, plant-derived medicines are gaining wider acceptance even in developed countries of the Western world. More than 50% of all drugs currently in clinical use are of natural origin. Plants are therefore emerging as a novel sourc...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Tania Chakraborty Source Type: research

< em > Gmelina arborea < /em > : chemical constituents, pharmacological activities and applications
Gmelina arborea(G. arborea) is a bio-prospective plant belonging to family verbenaceae. It is widely used for it ’s medicinal properties from ancient times. The present paper comprehensively reviewed the traditional uses, medicinal properties and chemical constituents isolated fromG. arborea based on literature reported as well as critical analysis of the research. The present article is aimed to provide information on recent advances and new foundations and direction for further exploringG. arboreafor its applications. Pharmacological research reviewed thatG. arboreapossess various medicinal properties and biological  ...
Source: International Journal of Phytomedicine - December 27, 2017 Category: Science Authors: Charu Arora Source Type: research

Bone regenerative effect of aqueous < em > Cynanchum wilfordii < /em > extract in receptor activator of nuclear factor- κB ligand-induced osteoclast differentiation and estrogen deficiency-induced osteoporosis
Osteoporosis increases with age, most frequently in postmenopausal women because of reduced ovarian hormone levels. Furthermore, estrogen deficiency impairs trabecular metaphyseal bone. Although efficacious, long-term hormone replacement therapy (HRT) has estrogen-like side effects including breast and endometrial cancers, and non-hormonal or herbal therapies may be safer alternatives. Therefore, the aim of this study was to investigate the effects of aqueous extracts ofCynanchum wilfordii (CWW) on receptor activator of nuclear factor- κ B (NF-κ B) ligand (RANKL)-induced osteoclast differentiationin vitro and ovariectomy...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Woojin Jun Source Type: research

Traditional uses of wild medicinally important plants of Batkhela, kpk, Pakistan
The present study was carried out in Sangina valley of Batkhela, Malakand District, Khyber Pakhtunkhwa Pakistan. The aim of the current work was the documentation of plants utilized by the local inhabitants for different medicinal purposes.   Majority of cases utilized same plant species in several ways for distinct remedies. After collecting informations through an open-ended questionnaire, totality of 46 plant species used for different medicinal purposes were recorded in the study area belonging to 31 families. Family Lamiaceae ran ked as top by contributing 10.86% to the total documented medicinal plant species in the...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Fayaz Ali Source Type: research

Cardioprotective Potential of Methanol Extract of < em > Polygonum glabrum < /em > on Isoproterenol Induced Myocardial Necrosis in Rats
Conclusion: The present investigation indicates thatPolygonum glabrum could protect myocardium from isoproterenol induced necrosis. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Raja S Source Type: research

Aloe-emodin triggers ROS and Ca 2+ production and decreases the levels of mitochondrial membrane potential of human brain capillary endothelial cells
Conclusions: Our results collectively indicat e that AE inhibits proliferation of human brain microvascular cells via a mechanism involving ROS generation, disruption of Ca 2+ homeostasis and mitochondrial damage. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Ivanka Dimova Source Type: research