International Journal of Phytomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Pharmacological Evaluation and Antifertility Activity of Aloe barbadensis Linn on female wistar rats.
Ethanolic and Aqueous extract of Leaf ofAloe barbadensiswas study, antifertility activity in proven fertile female Wistar Rats at the doses 500mg/kg b.wt./day for 30 days. Different parameters were studied in female wistar rats including effect of Reproductive outcome, Anti-implantation, Abortifacient study and Estrogenic and Anti-estrogenic activity, Phytochemical were observed.,Aloe vera Leaves shown positive test for Alkaloids, Steroid, Flavonoids, Terpene, Carbohydrates and Tannin. The extract ofAloe vera has anti-fertility effect the control rats showed good number of litters. Treatment of animal with different extrac...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Sunil Kumar Shah Source Type: research

Estrogenic and anxiolytic effects of the decoction of stem bark of Khaya anthotheca (Welw.) C.DC (Meliaceae) in ovariectomised Wistar rats
Khaya anthotheca (Welw.) C.DC (Meliaceae) is a plant used in Cameroon to alleviate vaginal dryness in postmenopausal women and is also known to have anxiolytic properties.This work was designed to evaluate estrogen-like effects of this plant on primary estrogens targets of ovariectomized adult rats, as well as to evaluate its anxiolytic activities in the elevated plus-maze (EPM) test. In the 3-day uterotrophic assay, the extract increased (p< 0.01) the size of the vaginal epithelia and stimulated the acini differentiation of the mammary gland. In the EPM test, the extract increased the percentage of number of entries (p...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Germain Jean Magloire Ketcha Wanda Source Type: research

Documentation of Ethnoveterinary Practices in the CKNP Region, Gilgit-Baltistan
Majority of the livestock holders in different areas of Central Karakoram National Park (CKNP) region in Gilgit-Baltistan lack the modern veterinary healthcare facilities. The local community mostly depends upon the traditional floral therapeutic veterinary practices for the cure of various livestock diseases. The lack of the ethnoveterinary surveys in the CKNP region results in loss in the scientific documentation of the traditional information and practices about the livestock healthcare.The present study deals with the documentation of the livestock diseases and the ethnoveterinary herbal and non-herbal therapeutic prac...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Iftikhar Ali Source Type: research

Protective role of Bacopa monnieri against Rotenone- induced Parkinson ’s disease in PC 12 cell lines
Parkinson disease (PD) is a chronic neurodegenerative disorder characterized by the loss of dopaminergic (DA) neurons in the substantia nigra, decreased striatal dopamine (DA) levels, and consequent extrapyramidal motor dysfunction. PC 12 cells originate from pheochromocytoma cells of rat adrenal medulla and share many common characteristics with substantia nigra cells. They produce DA, several growth factors, such as nerve growth factor, fibroblast growth factor and transforming growth factor, and express DA receptors. Hence,these cells are being used to study the alterations in dopaminergic neurons, in vitro, that occu...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Gunduluru swathi Source Type: research

The Phytochemical Investigation and Biological Activities of Berberis Orthobotrys 
The leaf extract ofBerberis orthobotrysBien. ex Aitch.(B.o.)afforded three compounds viz., β-sitosterol (1), sesamin (2) and 10-eicosanol (3) which were identified by spectroscopic methods including 1D and 2D NMR, GC-MS, IR and comparison of their spectral data with the published data. To the best of our knowledge these three compounds are reported here for the first time to be isolated fromBerberis orthobotrysBien. ex Aitch.(B.o.). Moreover the root extract exhibited good antilieshmanial activity and root and fruit extracts demonstrated minor antifungal activity againstFusarium solani. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Akber Dad Source Type: research

A supposed mechanism of synergistic action of catechol-containing natural polyphenols
Over the past decades, accumulated evidences have been published about different synergistic biological activities between natural dietary polyphenols. Although these effects could be physiologically important in chemoprevention, cardioprotection and neuroprotection, but probably also in treatment of serious chronic diseases, such as cancer, the exact mechanisms behind this potentiation have still remained largely unknown. In this article, supposition about the involvement of phase II metabolic enzyme, catechol-O-methyltransferase (COMT), in the synergistic action of catechol-containing polyphenols is proposed. Serving as ...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Katrin Sak Source Type: research

Algae as potential repository of anti cancerous natural compounds
Algae constitute a promising source of novel compounds with potential as human therapeutic agents. In particular, algae have been considered as a potential source of new bio-active compound. Algae possess several biological activities, including anticancer activity. This review provides a comprehensive report on the several genera of algae belonging to Chlorophyceae, Pheophyceae and Rhodophyceae having anti-proliferative, apoptotic, anti angiogenic as well as cytotoxic efficacy and their mode of actionin vitro as well asin vivo condition. Algae are extensively used as functional foods and medicinal herbs, and have a long h...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Ankita Mridha Source Type: research

Phytotherapeutical implications in pain perception - focusing on schizophrenia
Schizophrenia is an extremely complex psychiatric disease where perception of pain is altered, varying from abolition to lack of any kind of changes compared to normal controls and even hypersensitivity. In this way, the hypothesis of amending schizophrenia through pain therapy enhanced the importance of pain medication. But managing pain phenomenon in schizophrenia has large and unknown implications. Nevertheless, pharmacological interactions between the medications for these two entities are unknown and most likely would have a lot of side-effects and therefore ethnopharmacological methods became once again an interestin...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Iulia Antioch Source Type: research

Metabolic profile and atherogenic indices of rats treated with Tamarindus indica and Mentha piperita juice.
Changes in diet, physical inactivity and stress contribute to obesity, cardiovascular disease and atherosclerosis. Literature shows that bioactive compounds may result in benefits to human health. The aim of this study was to evaluate the glycemic, lipid profile and atherogenic indices of Wistar rats treated withMentha piperita andTamarindus indica juice. Animals received food and waterad libitumand were divided into 3 groups: control group (G1) that received 0.5 mL of water twice daily;Menthagroup (G2) treated with 0.5 mL of mint juice and group treated withTamarindus indicajuice (G3), that received 0.5 mL of tamarind ...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Sandra Maria Barbalho Source Type: research

Antioxidant and Antiulcer Potential on leaves of Brassica nigra L. against Gastric Ulcer
In the present study, anti-ulcerative effects ofextract ofBrassica nigra L. leaveswere investigated in pylorus ligation and aspirin-induced gastric ulcer models in rats.In this model, ethanolic extract ofBrassica nigraL. leaves and omeprazole showed a significant reduction in free acidity, total acidity and ulcer index (p<0.001, p<0.01, p<0.05) when compared to control. The percentage of ulcer inhibition was observed in pylorus ligated model was as follows: standard, BNLE 100mg/kg, BNLE 200mg/kg and BNLE 300mg/kg 55.76%, 30.96%, 49.54% and 51.35% respectively. In present study antiulcer effect of ethanolic extract...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Rakesh Punekar Source Type: research

Curative effect of Plumbago indica root extract on thioacetamide induced hepatotoxicity in experimental rats
The root parts ofPlumbago indica is widely used in the Indian Ayurvedic traditional system. The study was designed to evaluate the hepato curative activity Plumbago Indica (PLBM) methanolic root extracts at different doses (100 and 200 mg/kg bw) against thioacetamide induced liver damage in albino wistar rats. Liver damage was induced by administration of Thioacetamide (100 mg/kg bw) and was assessed by evaluating the activity of liver-function marker enzymes, antioxidant enzymes and lipid peroxidation. The liver sections were evaluated for histopathological changes. PLBM significantly (p≤ 0.05) reversed the elevation of...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Eldhose Binil Source Type: research

Phytochemical evaluation and antioxidant assay of ethanolic extracts of traditional medicinal plants ( Ferula assafoetida, Saussurea costus, Peganum harmala ) in oman
Ferula assafoetida, Saussurea costus and Peganum harmala are considered an important traditional folk medicines in Oman, extracts of these plants were screened for assessing bioactive phytochemical constituents and their antioxidant property. Total phenolic and flavonoid contents were evaluated to explore the reliable and potential sources of novel natural antioxidants. Preliminary phytochemical screening of different plant extracts and phytochemical investigation showed variations in the presence and amount of active ingredients. All the fractions ofP.harmala,S.costus and F.assafoetida haveflavonoid and phenolic compoun...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: S Hemadri Reddy Source Type: research

Immunomodulatory and antiarthritic activities of Smilax zeylanica
This study was designed to investigate the immunomodulatory and antiarthritic activities ofSmilax zeylanica.Methanolic extract ofSmilax zeylanica(MESZ) roots was tested for its immunomodulatory activity by NBT reduction test. Antiarthritic activity of the same was tested byin vitroprotein denaturation andin vivocomplete Freunds adjuvant (CFA) induced arthritis.MESZshowed its significant effect on both cell mediated and humoral immunity to suppress stimulated immune responses in NBT reduction test . It also markedly inhibited protein denaturation inin vitromodel. Extract at 200 mg/kg and 400 mg/kg showed statistically signi...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: P Veeresh Babu Source Type: research

Antimicrobial activity of marine algal extracts
Total, hydrophilic and lipophilic extracts of 21 marine algae species (2 species of Chlorophyta, 11 of Phaeophyceae and 8 of Rhodophyta) collected along the coast of Russian Far East were screened for antimicrobial activities (againstStaphylococcus aureus,Escherichia coliandCandida albicans). Among the macroalgal extracts analyzed, 95% were active against at least one of studied microorganisms, while 80% of extracts were active against two or more test strains. Broad-spectrum activity against three studied microorganisms was observed in the 35% of extracts from tested species of marine seaweeds. The results of our survey d...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Ekaterina A Chingizova Source Type: research

Proximate composition, antioxidant activities and phenolic composition of Cucumis sativus forma hardwickii (Royle) W. J. de Wilde & amp; Duyfjes
In the present investigation, nutritional, anti-nutritional and antioxidant potential of Cucumis sativus forma hardwickii was evaluated for the first time. The results revealed that leaf and fruit of Cucumis sativus f. hardwickii were rich source of ash, carbohydrate, fat, fibre and proteins. In addition, appreciable amounts of Vitamin C and E were also observed. Considerable antinutritional factors in leaf and fruit were noted which can be reduced by different processing methods. In sequential solvent extraction, methanol found to be the best in the extraction of antioxidants, which was supported with the highest antioxid...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Usmangani A Attar Source Type: research