Chemical composition, antioxidant and antimicrobial activities of stem barks of < em > Englerina gabonensis < /em > Engler and < em > Sterculia tragacantha < /em > Lindl from Gabon
Aim of this work was to evaluate the phytochemical constituents, antioxidant and antimicrobial potential of water-acetone, water-ethanol and water extracts ofEnglerina gabonensis andSterculia tragacantha.Presence of phenols was evaluated to estimate the effects of plants on microbial diseases. Water-acetone, water-ethanol and water extracts were examined for antioxidant activities. All plant extracts were tested against six reference strains, eleven clinical isolates and two fungal strains.Phenolic content were highest in the water-acetone and water-ethanol extracts fromEnglerinagabonensis in comparison withSterculia traga...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: C édric SIMA OBIANG Source Type: research

Evaluation of the anti-inflammatory effect of Yograj Guggul: an in vitro study
Yograj Guggul (YG) is a poly-herbal formulation extensively used by Ayurvedic practitioners to treat inflammatory conditions. However there are no reports evaluating its effect on the various enzymes involved in the inflammatory pathway. Hence the present was carried out to evaluate the anti-inflammatory effect ofYG, on inhibition of Cyclooxygenase (COX) - 1& 2 and 5-Lipoxygenase (LOX) enzymesin vitro. Three concentrations (25, 50 and 100 µg/ml) of the aqueous extract ofYGwere studied on the inhibition of COX 1& 2 and 5-LOX enzymes by Enzyme Immuno Assay (EIA). Aspirin was used as a positive control at concentrati...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Supriya Bhalerao Source Type: research

Analgesic and acute inflammation properties of the aqueous extract of dried leaves of < em > Paullinia Pinnata < /em > (Sapindaceae) Linn
This study was undertaken to assess the analgesic and anti-inflammatory effects ofPaullinia Pinnata.The analgesic activity was evaluated by using behaviour pain model in mice. The anti-inflammatory activity was carried out by using carrageenan, dextran, histamine and serotonin induced inflammation in rat. The extract was administered orally at a dose of 200 and 400 mg/kg. The results showed that the extract significantly (P< 0.001) reduced the number of writhing induced by the acid acetic. The aqueous extract reduced significantly (P< 0.001) the paw licking time in formalin model. The effect of the extract (200mg/kg)...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Dingom Aurelie Taylor Patience Source Type: research

Effect of phenolic extracts of Algerian medicinal plants on the bacterial growth and adherence of Staphylococcus aureus and Bacillus cereus pathogens responsible of food poisoning.
Artemisia, one of the larger genera in the family Asteraceae, comprises from 200 to more than 500 taxa at the specific or subspecific level. Artemisia herba-alba Asso (Shih) is grown in North Africa and certain parts of Asia and Middle East. It is one of the most widely used plants in the Algerian folk medicine. The antioxidant and free radical scavenging activities of the methanolic extracted materials were tested together with their antibacterial effects against isolated bacterial strains causing food poisoning. In summary,A. herba-alba Asso represent a good phenolic and flavonoid content (161, 64 mg/g and 16,83mg/g, res...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Imane Belkacem Source Type: research

Traditional uses of wild medicinally important plants of Sangina valley of Batkhela, kpk, Pakistan
The present study was carried out in Sangina valley of Batkhela, Malakand District, Khyber Pakhtunkhwa Pakistan. The aim of the current work was the documentation of plants utilized by the local inhabitants for different medicinal purposes.   Majority of cases utilized same plant species in several ways for distinct remedies. After collecting informations through an open-ended questionnaire, totality of 46 plant species used for different medicinal purposes were recorded in the study area belonging to 31 families. Family Lamiaceae ran ked as top by contributing 10.86% to the total documented medicinal plant species in the...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Fayaz Ali Source Type: research

Bone regenerative effect of aqueous Cynanchum wilfordii extract in receptor activator of nuclear factor- κB ligand-induced osteoclast differentiation and estrogen deficiency-induced osteoporosis
Osteoporosis increases with age, most frequently in postmenopausal women because of reduced ovarian hormone levels. Furthermore, estrogen deficiency impairs trabecular metaphyseal bone. Although efficacious, long-term hormone replacement therapy (HRT) has estrogen-like side effects including breast and endometrial cancers, and non-hormonal or herbal therapies may be safer alternatives. Therefore, the aim of this study was to investigate the effects of aqueous extracts ofCynanchum wilfordii (CWW) on receptor activator of nuclear factor- κ B (NF-κ B) ligand (RANKL)-induced osteoclast differentiationin vitro and ovariectomy...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Woojin Jun Source Type: research

Knowledge, Practice And Use Of Aegle Marmelos (L.) Correa Leaves Among Naturopathy And Ayurvedic Practitioners Of Vadodara City and Desk Review On Various Commercial Formulations available In Health And Disease Specially Diabetes
ConclusionsBaelleaves were reported to be used by these practitioners as anti-diabetic agent. This information extracted warrants further clinical trials to prove the efficacy of the anti-diabetic properties of these leaves. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Vinita Gopalchandra Nigam Source Type: research

Assessment of the antibacterial activity of four essential oils and the biobactericide Neco.
The purpose of this study was to assessin vitro the activity of four essential oils (Cymbopogon citratus, Eucalyptus citriodora, Lippia multiflora, Melaleuca quinquenervia) and the biobactericide Neco ® on Gram-positive bacteria.The aromatogram and antibiogram were assessed by the agar well diffusion method and the Muller Hinton disk-agar diffusion method, respectively. Also, the minimum inhibitory concentration and the minimum bactericidal concentration were determined by the microdilution method in liquid medium.The aromatogram showed that the biobactericide Neco ® induced the largest inhibition diameters (34.53 ± 11....
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Jean-Fabrice Yala Source Type: research

A Study on the Ethanolic Extracts of Red Seaweed- Gracilaria corticata (J.Agardh) J. Agardh, to Assess the Antiproliferative Activity and Morphological Characterization of Apoptosis on HeLa Cell lines
Marine algae are excellent source of bioactive compounds that can be used as an alternative source for finding novel anti-cancer molecules. Gracilaria corticata, red algae from Surathkal beach, Karnataka were studied for their anti-proliferative activities and their morphological characterization on HeLa cells were assessed. Cytotoxicity of the algal ethanolic extracts on HeLa cells were assayed by 3-(4,5-dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide (MTT) reduction method. Morphological assessment was done by examinations with Hoechst staining and acid vacuoles were determined using acridine orange. Induction of...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Ashwini S Source Type: research

Antiviral activity and Antioxidant role of phenolics from < em > Sophora interrupta < /em > Bedd in NDV induced oxidative stress in chickens
The present investigation is taken up to evaluate the antiviral efficacy of phenolics isolated fromSophora interruptaBedd and their antioxidant role in the brain and lungs of chicken during Newcastle disease virus (NDV) induced oxidative stress. The activity levels of selected antioxidant enzymes such as superoxide dismutase (SOD), catalyse (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and glutathione-S-transferase (GST) levels were significantly decreased in brain and lung tissues of  NDV infected animals over controls causing oxidative stress. In addition, histopathological alterations disclosed that l...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Cherukupalle Bhuvaneswar Source Type: research

Evaluation of chemical profile and antioxidant potential of < em > Trichodesma indicum < /em > (L.) R.Br.
The present study was conducted to evaluate the antioxidant activity and chemical composition of aqueous methanolic extract ofTrichodesma indicum(L.) R.Br. The extract was tested for antioxidant activity using variousin vitro models viz., DPPH, ABTS, NO, FRAP, total antioxidant activity and reducing power. The total phenolic and flavonoid contents were found to be equivalents to 97.83 ± 0.08 µg of gallic acid and 45.45 ± 0.19 µg of rutin /mg of dried aqueous methanolic extract, respectively. Among various antioxidant assays performed, maximum inhibition was observed in the ABTS (IC50 17.13 ±  0.23 μg) followed by DP...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Mahendra S Khyade Source Type: research

Investigation of antioxidant properties of < em > Withania somnifera < /em > (L.) Dunal and influence of physico-chemical properties of soil along the topographic gradients in sub-tropical region of the Indian Himalaya
A high value medicinal plantW. somniferaL. Indian Ginseng; Ashwagandha investigated for the antioxidant and influence of physico-chemical properties of soil on antioxidant   along the topographical gradients in Kullu Valley, North Western Indian Himalaya. Total phenolic and flavonoid contents in methanol extracts of fruits, leaves, stems and roots were quantified and their antioxidant activities were evaluated using thein-vitro assays such as DPPH, ABTS and FRAP. The study revealed that fruits, leaves, stems and roots ofW. somnifera were potent source of natural phenolics and flavonoids and possesses antioxidant activitie...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Kundra R Source Type: research

Comparative screening of in-vitro free radical scavenging, anti-inflammatory and anti-haemolytic activities from non-polar solvent extracts of < em > Pterocarpus marsupium < /em >
Pterocarpus marsupium is widely used as ‘Rasayana’ in ayurvedic system for curing several medical ailments. In view of this, petroleum ether and chloroform extracts ofPterocarpus marsupium bark was scrutinized to unfold free radical scavenging by measuring their capability for scavenging DPPH radical, ABTS, phosphomolybdenum assay as well as reducing power capacity assessment and anti- inflammatory activity by inhibition of protein denaturation. Additionally, RBC ’S were also used to explore the potentiality ofPterocarpus marsupiumdifferent extracts to shield RBC in oxidative stress condition. Chloroform extract show...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Aruna LH Source Type: research

< em > Cordia macleodii < /em > Hook f. Thomson-A potential Medicinal Plant
Cordia macleodii Hook. f.& Thoms. belongs to family Boraginaceae, is an   endangered medicinal plant, commonly known as “Dahiman” or “Dahipalas”. It is distributed in moist and dry deciduous forests of India such as Chhattisgarh, Madhya Pradesh, Odisha, Chotanagpur and is widely used to cure various diseases. These bioactive compounds made this plant as a valua ble potent herbal drug. It contains various bioactive compounds including Phenols, Terpenoids, Saponins, Volatile oils, Flavonoids, Glycosides etc. This review presents the pharmacological property, phytochemical constituents, traditional uses and biolo...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Jagriti Chandrakar Source Type: research

< em > Pistacia integrrima < /em > Stewart ex Brandis: a less known high value medicinal plant
The family Anacardiacea, best represented by the speciesPistacia integrrimaStewart ex Brandis, is known worldwide for its manifold uses. It is widely used to cure various diseases like cold, cough, asthma, fever, vomiting and diarrhea, etc., and widely used in modern medicine. Therefore, an attempt has been made to assess the medicinal potential of the species both in traditional as well as in modern medicine system. These properties are supposed to be cured by different active compounds present in the plant. This paper provides the relevant information about medicinal properties of this high value medicinal plant.   (Sou...
Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Bharti Sharma Source Type: research