International Journal of Phytomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Phytochemical analysis, anti-oxidant and anti-microbial activity of Acalypha indica leaf extracts in different organic solvents
The herbAcalypha indicawhich belongs to Euphorbiaceae family has multiple medicinal properties which include anti-oxidant, anti-bacterial, anti-fungal, anti-inflammatory, antiulcer, anti-helmintic, anti-cancerous, anti-venom, and neuro-protective activity. The present study was designed to evaluate the phytochemical, antimicrobial and anti-oxidant activity ofAcalypha indicaleaves extracts in different solvent extractions like methanol, hexane, ethyl acetate and petroleum ether. Fresh leaves of the plant were collected and shade dried. Dried leaves were milled to obtain powder. Powder was subjected to soxhlet extraction usi...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Chekuri Sudhakar Source Type: research

 In silico investigations revealed four potential colon cancer drugs from phytochemicals in Zingiber officinale 
This study therefore investigated the potential colon cancer drug of compounds found in ginger. Dihydropyrimidine dehydrogenase was modeled using comparative homology modeling and virtual screening was performed locally on a Linux platform using AutoDock Vina®. The results showed that human dihydropyrimidine dehydrogenase is a homolog of pig dihydropyrimidine dehydrogenase. The leads of potential colon cancer drugs were beta-sitosterol, 6-Shogoal, Alloaromadedrene, and Zingiberol. They had similar binding site with levamisole for tumor necrosis factor ligand superfamily member 6 with His 148 and Tyr 192 common at their bi...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Fortunatus Chidolue Ezebuo Source Type: research

Consumption of Moringa oleifera flour and its effects on the biochemical profile and intestinal motility in an animal model
The objective of this study was to evaluate the effects of MO flour in anthropometric and biochemical profile of Wistar rats. Animals were divided randomly into the following groups (n=10): G1 (control group) and G2 (treated with MO flour mixed to the rat food) were both treated for 40 days and G3 (control group), G4 (treated with senne) and G5 (treated with MO flour) were studied to evaluate the intestinal motility. After 40 days, animals of G1 and G2 were euthanized and evaluation of glycaemia, total cholesterol, triglycerides, LDL-c, VLDL-c, HDL-c, C reactive Protein (PCR), hepatic enzymes, Lee Index, weight and viscera...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Elen Landgraf Guiguer Source Type: research

Phytochemical analysis and DPPH scavenging activity of Combretum punctatum var. squamosum (Combretaceae), an ethnomedicinal plant of Mizoram.
The main objective of the study is to determine the phytochemical constituents and the DPPH scavenging activity of the aqueous extract ofCombretum punctatum var.squamosum. The phytochemical screening revealed that the crude aqueous extract contained phenols, flavonoids, phytosterols and diterpenes while alkaloids, glycosides, tannins, carbohydrates, proteins and amino acids were found to be absent. The total phenol and flavonoid content in the crude aqueous extract was found to be comparatively high, i.e. 111 mg/g GAE and 120.99 mg/g QE respectively. It was also found that the % DPPH scavenging activity was very high and...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Kawl Thanzami Source Type: research

In-vitro scavenging activity and acute toxicity study of methanol leaves extract and fractions of Lophira lanceolata Tiegh. Ex Keay (Ochnaceae) in rats.
The present study aims at comparingin-vitroscavenging activities of methanol extract and fractions ofLophira lanceolata leaves, and also to study the oral acute toxicity of the ethyl acetate fraction.Petroleum ether, dichloromethane, ethyl acetate, butanol and water fractions were prepared from the methanol extract of the plant. The scavenging activity of DPPH (2, 2-Diphenyl-1-picrylhydrazyl), the total phenolic (TPC) and total flavonoid (TFC) contents of the extract and fractions were determined by spectrophotometrical methods using gallic acid (GA) and quercetin (Qu) as reference antioxidant. The fifty percent inhibitory...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Jean-Baptiste N. Oussou Source Type: research

Possibilities of developing novel potent antitumor agents from the leaves of Cryptomaria japonica 
This study shows efficacy of methanolic extract of leaves ofCryptomeria japonicaas a probable antitumor/anticancer agent. Phytochemical analysis of the extract showed presence of flavonoids, which are known to possess significant anticancer activity. Thus there is a definite possibility of developing novel anticancer drugs from such plant products (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Laxmi Rani Basu Source Type: research

HPLC-UV profile of Genista ulicina Spach. (Fabaceae) extracts and in vitro antioxidant activity
To perform a qualitative and quantitative analysis of the phenolic and flavonoid contents and evaluate the antioxidant activity of ethyl acetate (EtOAc) andn-butanol (n-BuOH) extracts of the aerial parts ofGenista ulicinaSpach. from Algeria.The qualitative analysis of plant extracts was carried out by RP-HPLC using UV detector, whereas the quantification of total phenolic and flavonoid contents was completed according to the Folin-Ciocalteu procedure and aluminium chloride colorimetric method respectively. To evaluate the extract ' s antioxidant activity, Two in vitro antioxidant tests were employed: DPPH and β-carotene b...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Kaoutar Chebbah Source Type: research

Anti-diabetic effect of aqueous fruit extract of Borassus aethiopum (Mart.) in alloxan-induced diabetic rats
Conclusion: The aqueous fruit extract of B. aethiopum is antidiabetic. It was also found to be nephron- and hepato-protective as well as boosting the immunity of the animals. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Christopher Larbie Source Type: research

Preliminary phytochemical screening and hepatoprotective activity of methanol extract of Artocarpus hirsutus leaves.
The objective of the present work was investigating the preliminary phytochemical screening and hepatoprotective activity of methanol extract of the leaves ofArtocarpus hirsutus.Group I served as vehicle control, Group II served CCL4(2ml/kg, s.c.), Group III served as standard Silymarin (50 mg/kg, p.o.) Group IV and V served as methanolic extracts ofArtocarpus hirsutus(MEAH) at the dose level (250 and 500 mg/kg, p.o.). The degree of protection was determined by measuring level biochemical marker like alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), direct bilirubin, total bil...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Jitendra Patel Source Type: research

Evaluation of the estrogenic properties of aqueous extracts of Tragia benthamii Baker (Euphorbiaceae) and Graptophyllum pictum (Acanthaceae) and their ability to alleviate some menopausal symptoms induced by ovariectomy in Wistar rats
Tragia benthamii Baker (Euphorbiaceae) andGraptophyllum pictum Linn (Acanthaceae) are two Cameroonian medicinal plants traditionally used against female reproductive tract disorders, during and after the reproductive period, and as an abortifacient. Since there were no scientific data supporting the above claims and pharmacological studies characterizing their estrogenic properties, we therefore aimed to evaluate their ability to induce estrogen-like effects on primary estrogens targets, uterine, vagina and mammary gland; as well as their ability to alleviate hot flushes in ovariectomized adult rats. For this purpose, we a...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Germain Jean Magloire Ketcha Wanda Source Type: research

Spraying of swine buildings with lemon grass ( Cymbopogon citratus ) essential oil does not produce blood absorption in swine
Cymbopogon citratus(Lemon grass)essential oils have been used in swine buildings to reduce the offensive odor emanating from swine buildings. The present study was designed to investigate plasma residues of citral which is a major constituent of the essential oils ofCymbopogon citratus.An HPLC method was established, validated and used for the determination of citral in swine plasma harvested from blood samples taken at the 14th, 21st and 28th day after spraying swine buildings with the 3% Lemon grass essential oil. Thereafter, analysis of the sample wasconductedusing HP ODS Hypersil column (200 × 4.6 mm, 5 µm) with a mo...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Seung-Jin Lee Source Type: research

Effects of lycium and lycium-composed formula on the peripheral coldness induced by local cooling in mice
Recently people appealing for peripheral coldness increase. Lycium fruits have a long tradition of use in nutrition and traditional medicine in East Asia, while its effect on peripheral coldness is not yet investigated. We study the effects of lycium and lycium-rich formula (Ligustrum lucidum ait, LLA) on the peripheral coldness induced by local cooling in mice.7-week old male ddY mice were administered either water (control) or lycium or LLA for 2 weeks. After an aesthesia, the mouse body except for head was immersed into 10 ℃ water for 10 min. Then the skin surface and rectal temperature of mouse were measured with a t...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Jian-Rong Zhou Source Type: research

Cinnamic acid Supplementation Regulates the Production of Licochalcone A, Liquirtigenin and Licoisoflavone B in Glycyrrhiza glabra Callus Cultures.
This study dealt with the enhancement of flavonoids through precursor feeding in callus cultures ofG. glabraand investigated the influence of cinnamic acid on phenylalanine ammonia lyase (PAL) activity and production of licochalcone A, liquirtigenin and licoisoflavone B. Unorganized callus cultures were established from young leaf explants on Murashige and Skoog ’s (MS) medium supplemented with NAA (1mg/l), BAP (0.5 mg/l) and various concentrations of cinnamic acid. Flavonoids were obtained from calli through solvent extraction and were identified and quantified through Gas-Chromatography Mass spectrometry. Cinnamic acid...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: U. Vijayalakshmi Source Type: research

Evaluation of total phenolics, antioxidant and antiproliferative activities of rhizome extracts from select Zingiberaceae species in South India
This study aimed to evaluate total phenolic content, antioxidant and antiproliferative capacity of five different organic solvent extracts prepared from the rhizomes ofCurcuma mutabilis (CM), Curcuma haritha(CH), Curcuma neilgherrensis (CN) and Zingiber anamalayanum (ZA), four hitherto unexplored Zingiberaceae species. Folin-Ciocalteu method andDPPH radical scavenging assay were used to determine respectively the total phenolic content and antioxidantcapacity. The antiproliferative activity of the extracts were tested against four human cancer cell lines – K562, REH, Nalm6 and MCF7 to ascertain the IC50 values. ...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Soumya Tumbath Source Type: research

Phytochemical analysis and antibacterial activity of Khaya senegalensis bark extracts on Bacillus subtilis, Escherichia coli and Proteus mirabilis 
The aqueous and ethanol extracts of the bark of Khaya senegalensis were screened for their phytochemical constituents and preliminary antibacterial activity againstBacillus subtilis, Escherichia coli and Proteus mirabilis.The minimum inhibitory concentration (MIC) of the plant on the tested organisms was determined using multiple tubes method.Alkaloids, anthraquinones, glycosides, tannins and steroids were detected in both extracts.The ethanol and aqueous extracts of the plant showed antibacterial activity againstB. subtilis and E. coli, with the aqueous extracts having more activity than those of ethanol. However the grow...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Abdullahi Aliyu Source Type: research