International Journal of Phytomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Anti-leukemic activity of phosphoproteins from Sesamin via induction of nuclear antigen H731and CLIP-associating protein 2 isoform X25 mediated apoptosis
Leukemia is an uncontrolled proliferation hematopoietic cancer cells that commonly treats with conventional therapies such as chemotherapy. However, many side effects were reported. Alternative medicines have been developed by using natural or herb compounds as therapeutic drug. Sesamin, a class of phytoestrogen isolated from sesame seed displaying potent anticancer activity invitro and invivo.However, the mechanism by whichsesamin mediatesanticancer effects on leukemic cells are notfully understood. In thisstudy, the effects of sesamin on cell viability, cell apoptosis and expression of phosphoproteins in Molt-4 and NB4 l...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Pattharin Wannapruk Source Type: research

Sodium silicate mediated response of antioxidative defense system in Lycopersicon esculentum mill. under water stress
This study offers first hand information on the water stress-induced oxidative stress inLycopersicon esculentumand development of antioxidative defense system against drought.The results obtained clearly indicated the positive impact of sodium silicate in protection of tomato plants under water deficit condition. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Chanchal Malhotra Source Type: research

In Vitro antioxidant activity of Polygonum Glabrum 
Assessment of antioxidant activity was imperative in the screening of medicinal plants for potential health benefits. In present study methanol extract ofPolygonum glabrum (polygonaceae) was screened for its in vitro antioxidant activity using biologically relevant methodologies which scavenge radicals such as 1,1 diphenyl 2 picryl hydrazyl (DPPH), nitric oxide, hydrogen peroxide, hydroxyl, superoxide anion and 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS). Total reducing ability by conversion of ferric (III) to ferrous (II) and molybdenum (VI) to molybdenum (V), metal ion chelating c apacity and anti...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Raja sundara rajan Source Type: research

Phytochemical screening and influence of extraction solvents on antioxidant and antimicrobial activities of Asparagus racemosus willd. Root
The bioactive components present in theAsparagus racemosus root are known to be responsible for its medicinal properties. However, the solvent extraction for these bioactive components had effect on bioactive activities. The present study was aimed to compare the effect of using different extraction solvents to extract the active components, antioxidant and antimicrobial activities fromAsparagus racemosus root. Aqueous (DW and NW) extracts showed the efficiency ofAsparagus racemosus root as antioxidant agent and broad spectrum antibacterial agent against both Gram-positive and Gram-negative. 95% Ethanolic extract had the m...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Sirikhwan Tinrat Source Type: research

Ameliorative effect of Ficus dalhousiae Miq. (Moraceae) methanolic leaf extract on carbon tetrachloride induced hepatic and renal toxicity
This study demonstrates the mechanism of hepatoprotective and renal protective activity ofFicus dalhousiae Miq. (Moraceae) methanolic bark extract on carbon tetrachloride induced hepatic and renal toxicity. Shade dried powder was subjected to shoxlet extraction with methanol and assessed for hepatoprotective and renal protective activities. Hepatotoxicity and renal toxicity were induced in rats by single oral dose of CCl4 diluted with olive oil (1:1 v/v; ml/kg body weight) after pretreatment of methanolic extract for seven days. Sixteen hrs after CCl4 administration, rats were sacrificed and biochemical markers like Serum ...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Swati Kujur Source Type: research

GC/MS analysis, antimicrobial and Antioxidant Effect of Ethanol Garlic Extract
Conclusion: 75% ethanol garlic extract was the most efficient in considering the recovery rate, antimicrobial and antioxidant activities among the various extracts. Based on the above biological results, we could confirm this possibility as a feed additive for anti-salmonella infection. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Na-Hye Park Source Type: research

Identification of alkaloids in methanol extract from leaves of Semenovia suffruticosa when humic substances were added to its root soil in the primary growth
Alkaloids are a group of natural compounds originally found in plants.Suffruticosa is aspecies of the genusSemenovia, theApiaceous family, a native herb in Iran. In this family, alkaloids are found rarely. Humic substances application to the root soil at the beginning of plant growth improves quality, productivity and physical properties of the soil. Accordingly,humic substances were added separately to the root soil of the samples and other samples were selected as the blank plant sample in the distance of 50 cm. Methanol extracts were prepared from dried and powdered leaf samples. The crude alkaloid solution was extrac...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Alireza Sardashti Source Type: research

Evaluation of antidiabetic and antioxidative efficacy of ethyl acetate fraction of methanolic extract of Camellia sinensis (green tea) leaves in streptozotocin induced diabetic albino rat
Conclusion:From the results, it may be concluded that ethyl-acetate fraction of methanolic extract of leaves ofC. sinensis has a promising anti-diabetic and antioxidative activities for the management of streptozotocin induced diabetic state. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Baisakhi Biswas Source Type: research

Protective role of Broccoli powder against continuous ingestion of Escitalopram antidepressant drug induced hepatotoxicity in Swiss albino male mice
To investigate the protective role of broccoli powder “Brassica Oleracea Italica” against continuous ingestion of escitalopram antidepressant drug induced hepatotoxicity in Swiss albino male mice.Mice were divided into different groups. Group1: Normal control (0.9% NaCl), Group 2: Escitalopram drug treated only (20 mg/kg), Group 3: Broccoli powder with Escitalopram drug treated (200 mg/kg + 20 mg/kg), Group 4: Olive oil vehicle control, Group 5: Carbon tetrachloride (CCl4) referenced as positive control (33 mg/kg), Group 6: Broccoli powder with CCl4 treated (200 mg/kg + 33 mg/kg). The effect of these groups on liver ti...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Sneha Saxena Source Type: research

Need of an Ancient Roots to Modern Medicine in the Treatment of Cancer- A review
The already available expensive conventional therapies for cancer like chemotherapy and radiotherapy have a number of side effects such as myelosuppression and neurological, cardiac, pulmonary, and renal toxicity, which pose serious harm to the quality of life. Therefore, there is a need to develop treatment options that include more potent and less toxic anticancer drugs as compared to existing drugs. Studies have shown that regular consumption of fruits and vegetables because of phytochemical compounds extracted from them inhibiting the activity of antioxidant and free radicals which in turn showing anti-cancer activitie...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Manish Gunjan Source Type: research

Oral supplementations of Bauhinia variegata ’s leaf extract has anxiolytic effect and improves locomotory and exploratory behavior of female albino mice
Present study was designed to investigate the effects of 200 mg/ml solvent/Kg of body weight ofBauhinia variegata ’s leaf extract on neuromuscular coordination, locomotory and exploratory behavior of adult female albino mice. Six week old female albino mice were used as experimental animals. Mice were either orally supplemented with 200 mg/ml/Kg of body weightBauhinia variegata ’s leaf extract or with saline solution [0.9%] for 7 days. Behavioral observations were made by applying a series of neurological tests [Rota rod, Elevated plus maze, Light and dark box, Open field and Novel object test]. Exploratory and locomot...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Furhan Iqbal Source Type: research

Oxidative stress and inflammation caused by n-Hexyl salicylate in mouse skin: the effectiveness of flavonoids
Reactive oxygen species (ROS) play a role in a numbered of degenerative conditions including psoriasis. Psoriasis is a chronic inflammatory disease who ’s the etiopathogenesis is not yet completely understood, and therefore there is no standardized therapeutical approach. Flavonoids, recognized as potent antioxidants, are multifunctional molecules that can act as anti-inflammatory and antiproliferative agents through the modulation of multiple si gnaling pathways. The present study was designed to investigate the protective role of flavonoids [quercetin, chrysin, curcumin or Epigallocatechin 3-gallate (EGCG)] against n-H...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Nada Orsolic Source Type: research

Preliminary screening of Waltheria indica (L.) plant for its anti-inflammatory activity
The investigation on anti-inflammatory activity of the various extract ofWaltheria indicaL.was reported to find out the pharmacological basis for its ethnomedical use.The anti-inflammatory activity of the pet ether (PEW) and methanol (MEW) extracts of the leaves ofWaltheria indicaL. (Malvaceae)were evaluated by using in vivo (Carrageenan& histamine induced rat paw edema, cotton pellet granuloma test) models. It was observed that, all the extracts showed significant activity in the in-vivo model at the dose of 500 mg/kg b.w. orally, when compared with control and standard drugs. Of the two extracts tested, methanol extr...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Amol Chandekar Source Type: research

Hibiscus noldea (Malvaceae) Aqueous Extract Prevents Insulin Resistance and Protects Pancreatic Islets From Dexamethasone Damages in Rat.
Conclusion: The stem leaves aqueous extract fromHibiscus noldea have the ability to reduce insulinresistance via its antihyperglycaemic, hypolipidemic and antioxidant activities. These results justify the use of this extract in the management of diabetic state. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Ngueguim Tsofack Florence Source Type: research

Role of protective Pelargonium Sidoides root extract and Curcumin on Mushroom poisoning: An Experimental study in rats
Phalloidin is a cyclic heptapeptide containing cysteine amino acids. The toxicity of phallodin is attributed to the sulfur atom of the sulfur in the indole ring of the molecule and it is responsible for acute gastroenteritis occurring during the initial period of poisoning. Pelargonium sidoides, reinforcing the immune system, antiviral, has antibacterial properties as well as antioxidant properties.The aim of this study is to investigate the protective role of Pelargonium sidoides and Curcumin against mushroom poisoning.28 Wistar albino rats were divided into four groups. Group I; Along the study, 0.2 ml saline was admin...
Source: International Journal of Phytomedicine - July 4, 2017 Category: Science Authors: Velid Unsal Source Type: research