In-vitro antioxidant, Xanthine oxidase-inhibitory and in-vivo Anti-inflammatory, analgesic, antipyretic activity of < em > Onopordum acanthium < /em >
Onopordum acanthium (Scotch thistle) belong to Asteraceae (Compositae).O. acanthium is a flowering biennial plant native to Europe and Western Asia with coarse spiny leaves 20-50 cm in width with conspicuous and spiny-winged stems. We have previously reported pro-apoptotic and cytotoxic effect ofOnopordum acanthium crude extract against glioblastoma U-373 cells. The present study was designed to evaluate the cytotoxicity, antioxidant, xanthine oxidase inhibition, anti-inflammatory, analgesic, antipyretic activity of butanolic extract ofOnopordum acanthium. Cytotoxicity of different solvent (methanolic, butanol, chloroform ...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Sofiane Habibatni Source Type: research

Anticariogenic potential of < em > Potentilla fulgens < /em > extract and its chemical constituents
Streptococci andLactobacilli are the most common bacteria causing dental caries.Potentilla fuglens, native of north-east India is used by tribal people to cure teeth and gum problems. Based on its ethomedical use, its anticariogenic potential was evaluated. The crude methanol extract was found to have good anticariogenic potential. Epigallocatechingallate (4) was found to the most effective inhibitor against the tested bacterial strains. Epiafzelechin (4β→8) epicatechin (8)also demonstrated comparatively better activity than other dimeric compounds (MIC of 1.56, 3.12 and 3.12 μg/mL againstStreptococcus mutans,Lactobaci...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Alka Choudhary Source Type: research

< p align= " center " > The radical scavenging activity of 2-2 ’ diphenyl -1- picrylhydrazil (DPPH) on the methanol extracts and Ethyl acetate fractions of red dragon fruit peel  ( < em > Hylocereus polyrhizus < /em > (F.A.C.Weber) Britton dan Rose) < strong > < /strong > < /p >
This study tested the activity of radical scavenging of 2-2 ' diphenyl -1- pikril hidrazil (DPPH) in the methanol extract, as well as in the soluble and insoluble fractions of ethyl acetate of red dragon fruit peel. This research is carried out through various stages, such as: extraction and fractionation to obtain both insoluble fraction and soluble fractions of ethyl acetate. Antioxidant activity test is conducted by the method of thin layer chromatography and spectrophotometry.Antioxidant activity test, IC50values of methanol extract, ethyl acetate soluble fraction, and insoluble fraction of ethyl acetate had been obtai...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Sri Wahdaningsih Source Type: research

Protective role of Limonium bonduelli extract against non-enzymatic peroxidation in brain and testes induced by iron in vitro.
Infertility and Neurodegerative diseases have been linked to oxidative stress arising from peroxidation of membrane biomolecules and high levels of iron have been reported to play an important role. The present study sought to determine the antioxidant activity and protective ability ofn-butanol extract ofLimonium bonduelli on lipid peroxidation induced by FeSO4 in rat brain and testes homogenatesin vitro.n-butanol extract of the aerial parts (leaves and flowers)was prepared, and the ability of the extract to inhibit FeSO4 induced lipid peroxidation in isolated rat brain and testes was determined using spectrophotometric m...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Amel Amrani Source Type: research

Eco-friendly larvicide source from Acacia auriculiformis and its antimicrobial activity against clinical pathogens
Mosquito remains as a global threat for millions of lives since they serve as vector for most of the deadly pathogens and parasites. Several methods such as indoor spraying, insecticidal usage, and nets are employed to evade mosquito threat. However, the chemicals present in such compositions not only have negative impact on the human health and environment but also paves the way for the development of resistance in the insect vectors. Under such circumstances, novel and safer alternative tools have been recently researched to improve mosquito control. Medicinal plants species have been screened as a potential source for s...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Subbaraj Dinesh Kumar Source Type: research

Herbal Recipes used by traditional healers towards Reproductive and Urinary healthcare in Wayanad (Kerala) India.
The traditional healers in Wayanad (Kerala), India possess rich aboriginal herbal medicinal knowledge (AHMK). This investigation has brought in to light many valuable therapeutic measures which were at the verge of extinction. Validation and documentation of some of such valuable in formation was hence done in order to conserve at least a part of this aboriginal ethno medicinal heritage. The study consists of three consecutive phases. In the first phase a methodology for the study including work plan was elucidated. A field level testing of the method was executed at a selected study site. In the second phase an extensive ...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: EK Dilipkumar Source Type: research

Comparative studies on antisickling properties of brown and green leaves of < em > Carica papaya < /em > Linn. (Caricaceae)
This study was aimed at verifying the antisickling activity of the crude aqueous extract, crude methanol extract and fractions of dried brown and green leaves ofCarica papaya.The method used was the sickle cell haemoglobin polymerization inhibition experimentmeasured with the Ultra Violet (UV) spectrophotometer. Sodium metabisulphite was used as a deoxygenating agent while isotonic saline (0.9% NaCl) was used as the negative control and phenylalanine as a positive control. The results obtained showed that crude aqueous extracts of both the green and brown leaves exhibited high level of inhibition of sickled haemoglobin (Hb...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Glory Oluremilekun Ajayi Source Type: research

Composition and Biological Activities of different Date Seed varieties ( < em > Phoenix dactylifera < /em > ) of Oman: Cultivation Zone Influence
Date (Phoenix dactylifera L.) seeds (pits) account for ca. 10% of the date fruit and it is the date pits that present a major problem to the date palm industry in the USA as a waste product. Currently   date pits are employed as a food source for animals and poultry, as a soil fertilizer and also as a road base gravel In order to understand the varietal effects of Omani date seeds on the nutritional properties of dates and to explore the use of this waste product from the food industry, twent y two native date seeds (Phoenix dactylifera L.) including the varieties; Qushbu Narenjahn, Fardh, Naghal, Manhi, Qush Balquan, ...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Najeeb Ur Rehman Source Type: research

Prophylactic effect of herbal extracts on LPS-induced inflammatory response in rat hepatocytes
In conclusion, LPS-induced inflammatory response to rat hepatocytes could be inhibited byB. andC. vulgaris as naturally occurring prophylactics. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Mohamed S. Abdel-Latif Source Type: research

Phytochemical Screening and Biological Studies of Shilajit (Asphaltum)
Shilajit (asphaltum)   is produced  by the long term humification  of dead plant material  and organic vegetable matter  by different micro-organisms and has great potential for the treatment of a variety of human conditions.  This treatise reviews its origin, sources, chemical composition, biological  and  comm ercial importance. Phytochemical analysis was done by standard methods to evaluate  different Shilajit (asphaltum) classes of compounds in different samples of shilajit  which are responsible for their  biological activity.  Shilajit`s anti-microbial activity has been evaluated  against four di fferent...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Sidra Khaliq Source Type: research

Phytochemical and Biological Evaluation of < em > Justica adhatoda < /em >
Phytochemical and biological investigations were undertaken on  ethanolic extracts of the leaves and root bark ofJustica adhatodaL. Alkaloids, cardiac glycosides, tannins, steroids and saponins were detected in  extracts from both parts of the title plant. Reducing sugars  were not detected in  either extract whereas flavonoids were  detected in ethanolic extract ofJ. adhatotaleaves only.  Significant antibacterial and antifungal activities againstEscherichia coli,Staphylococcus aureus and Aspergillusniger were demonstrated by both the  leaf and root bark extracts. Additionally, both extracts  displayed good anti...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: Shahid Aziz Source Type: research

A review on Lantana rhodesiensis Moldenke: traditional uses, phytochemical constituents and pharmacological activities
Lantana rhodesiensis Moldenke an herbaceous, belonging to the Verbenaceae family is widely used in Africa folk medicine for the treatment of cancer, measles, malaria, smallpox, strength, coughs, fever, rheumatism, body pains, diabetes mellitus arrhythmia, parasitic diseases, arterial hypertension, old diarrhoeas. Many studies have been conducted on the chemical composition of the whole plant ofL. rhodesiensis as well as biological activities.  The aim of the present review was to give a detailed literature survey on its traditional uses, phytochemistry and therapeutical properties ofL. rhodesiensis. (Source: International...
Source: International Journal of Phytomedicine - April 30, 2017 Category: Science Authors: BANGOU Mindi édiba Jean Source Type: research

Evaluation of hepatoprotective effect of < em > Waltheria indica < /em > against various NSAIDs-induced hepatic damage in rats
The objective of the present study was to evaluate methanolic extract of leaves of Waltheria indica linn. for hepatoprotective potency of the potent solvent extract. The hepatotoxicity was induced by diclofenac, carbon tetrachloride (CCl 4 ) and acetaminophen. In CCl 4 induced hepatotoxicity study, animals were divided into five groups (n=6). Methanolic extract of Waltheria indica (WIM) groups were injected in doses of 400 mg/kg and 600mg/kg body weight along with CCl 4 and Silymarin 100mg/kg was taken as standard drug. Similarly procedure was followed in diclofenac and acetaminophen induced hepatotoxicity. Blood samples a...
Source: International Journal of Phytomedicine - March 30, 2017 Category: Science Authors: Amol Chandekar Source Type: research

Antioxidant and Antiulcer Potential on leaves of Brassica nigra L. against Gastric Ulcer
In the present study, anti-ulcerative effects of extract ofBrassica nigra L. leaves were investigated in pylorus ligation and aspirin-induced gastric ulcer models in rats. In this model, ethanolic extract ofBrassica nigraL. leaves and omeprazole showed a significant reduction in free acidity, total acidity and ulcer index (p<0.001, p<0.01, p<0.05) when compared to control. The percentage of ulcer inhibition was observed in pylorus ligated model was as follows: standard, BNLE 100mg/kg, BNLE 200mg/kg and BNLE 300mg/kg 55.76%, 30.96%, 49.54% and 51.35% respectively. In present study antiulcer effect of ethanolic extr...
Source: International Journal of Phytomedicine - March 30, 2017 Category: Science Authors: Atul Tripathi Source Type: research

Anti-Helicobacter pylori effect of the antioxidant extract from < em > Baccharis trimera < /em > Less. (DC)
One of the main risk factors for the development of stomach ulcers and cancer is infection with Helicobacter pylori bacteria, which is accompanied by considerable oxidative stress. Therefore, the aim of the present study was to assess the anti-Helicobacter pylori activity of B. trimera hydroalcoholic extract (HE) and aqueous (AqF), hexanic (HxF), and acetonitrile/chloroform (ACF) fractions, as well as their oxidant potentials.A preliminary phytochemical screening was carried out. Anti-Helicobacter pylori activity was assessed using a microdilution assay. After exposure to the investigated samples, the bacterial morphology ...
Source: International Journal of Phytomedicine - March 3, 2017 Category: Science Authors: Otal íbio Castiglioni Nunes Source Type: research