Eco-friendly larvicide source from Acacia auriculiformis and its antimicrobial activity against clinical pathogens

Mosquito remains as a global threat for millions of lives since they serve as vector for most of the deadly pathogens and parasites. Several methods such as indoor spraying, insecticidal usage, and nets are employed to evade mosquito threat. However, the chemicals present in such compositions not only have negative impact on the human health and environment but also paves the way for the development of resistance in the insect vectors. Under such circumstances, novel and safer alternative tools have been recently researched to improve mosquito control. Medicinal plants species have been screened as a potential source for secondary metabolites with larvicidal and antimicrobial properties. In view of such fact, the present study investigated the solvent extracts ofA. auriculiformisfor its antimicrobial, antioxidant and larvicidal properties against the malarial and Japanese encephalitis vectorAedes albopictusandCulexquinquefasciatus respectively. Results evidently showed that the ethanol, ethyl acetate, and water extracts inhibited the test pathogens significantly as compared to the other extracts at sub-MIC levels. DPPH and FRAP antioxidant studies elucidate, strong antioxidant potential of the ethanol and chloroform extracts ofA. auriculiformis. TLC profile of the ethanol extract showed six prominent bands with respectively coloured band patterns in the UV spectrum which corroborated with the presence of more than one active principles in the extract. The larvicidal activity ...
Source: International Journal of Phytomedicine - Category: Science Authors: Source Type: research