International Journal of Phytomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

An ethnomedicinal survey of medicinal plants from a sacred forest of Western Odisha, India.
Sacred forests are being protected by means of cultural and religious beliefs by the local communities and act as people participatory conservation sites for several important medicinal plants. Sacred forests are one of the oldest forms of biodiversity conservation sites still effectively managed by local people and act as in-situ conservation sites. In this context, the present study was carried out in Andhari sacred forest of Jharsuguda district as to collect the information regarding the traditional ethno medicinal knowledge acquired by the local medical practitioners. Only few indigenous people have adequate knowledge ...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Antaryami Pradhan Source Type: research

Physico-Chemical Evaluation for Allium hookeri Thw. Enum Leaves
Awareness and general acceptability of the natural products is increasing day by day because of its lesser side effect and cost factor. Above 80% of the world population is depending upon herbal medicines. Use of plants as medicine is the oldest practice that has been used in all countries from ancient time. Based on those old practices medicines of modern days are derived either directly or indirectly from the natural products. Manipur is one of the north eastern states of India and one of the hot spot areas of biodiversity, blessed with the amazing variety of flora and fauna.Allium hookeri belongs to Alliaceae family and...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Nepram Swarnalata Source Type: research

α-Amylase and α-Glucosidase inhibitory activity assessment of Cucurbita maxima seeds – a LIBS based study
The aim of the present study was to investigate, α-amylase and α-glucosidase inhibitory activities of the aqueous extract ofCucurbita maxima seedsin vitro and to correlate their activity with their phytoelemental profile quantitatively assessed by Laser-Induced Breakdown Spectroscopy (LIBS). Diabetes can be managed by controlling postprandial hyperglycemia which can be achieved by inhibiting carbohydrate hydrolyzing enzymes like α-amylase and α-glucosidase. Results reveal that theC. maxima seeds have appreciable α-amylase inhibitory activity of 46.03±1.37% with IC50 value at 7.00 ±0.29 mg ml-1 in addition to substan...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Devesh Kumar Kushawaha Source Type: research

Evaluation of central nervous system depressant activity of methanolic and petroleum ether extract of Manilkara zapota leaves (in vivo)
The purpose of this study was to examine the central nervous system (CNS) -depressant activity of methanolic and petroleum ether extracts of leaves obtained fromManilkara zapota(Sapotaceae)in vivo. CNS-depressant action was evaluated by observing the effects of plant extracts on both exploratory and spontaneous locomotor activity in mice using open field and hole cross tests respectively. The extracts were found to exhibit CNS-depressant activity in a dose-dependent manner. In the open field test, both the methanolic and petroleum ether extracts reduced the exploratory behavior of mice significantly (p<0.05). Although t...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Manirujjaman - Source Type: research

Need of standardization of herbal medicines in Modern era
The medicinal plants are important source for pharmaceutical manufacturing. Medicinal plants& herbal medicines account for a significant percentage of the pharmaceutical market. As the side effects of Synthetic medicine have started getting more apparent, majority of formulation are prepared from herbs. The herbal medicines however, suffer from lack of standardization parameters. The main limitation is the lack of standardization of raw materials, of processing methods and of the final products, dosage formulation, and the non existence of criteria for quality control. It is necessary to introduce measures on the regul...
Source: International Journal of Phytomedicine - November 8, 2016 Category: Science Authors: Anupam Kumar Sachan Source Type: research

Hepatoprotective Activity of Aqueous Extract of Sesbania grandiflora Linn Leaves against Carbon Tetrachloride induced Hepatotoxicity in Albino Rats
The present study was conducted to evaluate the hepatoprotective activity of aqueous extract of leaves ofSesbania grandiflora Linn (AESG) at the dose of 250 and 500 mg/kg body weight per oral using Carbon tetrachloride induced liver damage in wistar albino rats. Aqueous extract showed significant (p<0.05) hepatoprotective effect by lowering the serum levels of various biochemical parameters such as serum glutamic oxaloacetate transaminase (SGOT), serum glutamic pyruvates transaminase (SGPT), alkaline phospatase (ALP), total bilirubin (TBL), total cholesterol (CHL) and by increasing the levels of total protein (TPTN) and...
Source: International Journal of Phytomedicine - June 23, 2016 Category: Science Authors: Dayananda Bhoumik Source Type: research

Hepatoprotective Activity of Aqueous Extract of Sesbania grandiflora Linn Leaves against Carbon Tetrachloride induced Hepatotoxicity in Albino Rats
The present study was conducted to evaluate the hepatoprotective activity of aqueous extract of leaves of Sesbania grandiflora Linn (AESG) at the dose of 250 and 500 mg/kg body weight per oral using Carbon tetrachloride induced liver damage in wistar albino rats. Aqueous extract showed significant (p<0.05) hepatoprotective effect by lowering the serum levels of various biochemical parameters such as serum glutamic oxaloacetate transaminase (SGOT), serum glutamic pyruvates transaminase (SGPT), alkaline phospatase (ALP), total bilirubin (TBL), total cholesterol (CHL) and by increasing the levels of total protein (TPTN) an...
Source: International Journal of Phytomedicine - June 23, 2016 Category: Science Authors: Dayananda Bhoumik Source Type: research

Antiulcer And Antioxidant Potential Of Zizyphus jujuba Mill Root Extract In Aspirin And Ethanol Induced Gastric Ulcers.
The root of Zizyphus jujuba Mill. (Rhamnaceae) (ZJ) has been used to treat mouth ulcers as indigenous medicine. However there is no scientific report of its use for protection and treatment of gastric ulcers.The aqueous root extract of ZJ (AREZJ) was evaluated for antiulcerogenic potential in aspirin and ethanol induced ulcer models in Wistar rats along with in vitro antioxidants potential. Single dose toxicity studies were carried out to determine LD50.Two doses i.e. 150 and 250 mg/kg b.wt were evaluated for antiulcer activity by measuring ulcer index and percentage of ulcer healing in two of the ulcer models. Antioxidant...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Sameena Alam Source Type: research

Phytochemical Screening and Analgesic Activity of Opuntia ficus indica cladods extract in Wistar rats
The purpose of this work is the study of the peripheral and central analgesic activity of the Opuntia ficus indica cladods extract. Different concentrations are tested: 1000 mg/kg; 2000 mg/kg and 3000 mg/kg of body weight on rats by three different methods: the tail flick, the hot-plate and the writhing test to the acetic acid. The results obtained show that the aqueous extract of the cladods has an peripheral and central analgesic activity comparable to that of the Aspirin after administration to rats. The phytochemical analysis of the extract reveals the presence of tannins, coumarins, flavonoids, steroids and antho...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Sihem HALMI Source Type: research

Healing effects of quercetin on full thickness epidermal thermal injury in Wistar rats
This study was carried out to investigate the effect of quercetin on thermal injury healing in a rat model. Ninety female Wistar rats were used. Animals were inflicted with a reproducible full-thickness burn and randomized into three groups to receive no treatment (control group, CG), local application of a quercetin solution (quercetin group, QG) as well as application of the glyceryl trioctanoate, the solvent used to prepare the solutions (solvent group, SG). The size and healing progress of each wound was recorded and evaluated by means of clinical evaluation, planimetry and histological examination on days 0, 3, 6, 12,...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Efthalia Gouma Source Type: research

Mechanism of action of a bioassay-guided aqueous fraction of Pterocarpus marsupium Roxb hardwood on glucose-dependent insulin secretion
We previously demonstrated that a high molecular weight aqueous fraction of Pterocarpus marsupium Roxb. (PM) hardwood has insulinotrophic properties. However, the pharmacological mechanisms by which this fraction modulates insulin secretion remained unknown. The present study therefore isolated the insulinotrophic activity enriched fraction (AEF) from aqueous extract of PM and examined its pharmacological mechanisms. A bioassay method utilizing insulin secretion from mouse pancreas in vitro, was used to fractionate the insulinotrophic activity of PM and to delineate its pharmacological mechanisms. In addition, the effect o...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Suresh Kumar Mohankumar Source Type: research

Anti-androgenic, anti-oestrogenic and antioxidant activities of aqueous extract of Laportea ovalifolia on adults rats.
Cancer is one of the most life-threatening diseases in which deregulating proliferation of abnormal cells invades and disrupts surrounding tissues. It constitutes seriouspublic health problems in both developed and developing countries.To evaluate the anti-androgenic, anti-estrogenic and antioxidant activities of Laportea ovalifolia (L. ovalifolia) in order to contribute to the search and the valorization of medicinal plants which could reduce mortality related to prostate cancer.The evaluation of the anti-androgenic activity were carried out on castrated male rats receiving simultaneous daily administration of testosteron...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Sylvain Nguedia Njina Source Type: research

Genotoxic evaluations in Wistar rats of the hallucinogenic plant extract ayahuasca
This study evaluated the genotoxic, mutagenic and cytotoxic potential of ayahuasca in Wistar rats after a single oral dose. Rats of both sexes were randomly distributed into five experimental groups (n=10): negative control that received filtered water, positive control that received doxorubicin and treated groups that received ayahuasca at 1, 5 and 15 times the usual dose taken in human religious rituals. The rats were euthanized 30 hours after dosage. Genotoxicity was evaluated by flow cytometry, comet assay and micronucleus test. Renal, hepatic and pancreatic functions were evaluated by serum analysis. Ayahuasca showed ...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Aline Pic-Taylor Source Type: research

The Protective Effects of Curcuminand Caffeic acid alone or in combination onNicotine-induced Lung Injury in Rats
The present study was performed to explore the protective effects ofcaffeic acid (20 mg/kg.bw) and curcumin (50mg/k.g.b.w.) on nicotine-induced lung injury alone and in combination.Their effect was compared to N-acetylcysteine (500mg/k.g.b.w.) as known modulator of oxidative stress. Nicotine treatment (0.6mg/kg/day, i.p, for 21 consecutivedays) resulted in a significantincrease (p<0.05) in plasmaalanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C) and well as plasma and lung thiobarbitur...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Sylvia A. Boshra Source Type: research

Effect of Cnidoscolous aconitifolius (miller) i.m. Johnston leaf extract on sperm characteristics and reproductive hormones of male rats
The increase in population growth rate has prompted urgent need to search for plants with antifertility potentials. The present study is concerned with the evaluation of the effect of Cnidoscolous aconitifolius leaf ethanolic extract (LF) on sperm indices and reproductive hormones in male wistar rats.Eighteen male albino rats were divided into three groups (A,B,C) of six animals each. Group A (control) received distilled water while groups B and C received 250 and 500 mgkg-1 leaf extracts respectively on daily basis for fourteen days. Solvent partitioned fractions (n-hexane, dichloromethane, ethyl acetate and aqueous m...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Kolapo O Adeleke Source Type: research