Purification and characterization of α-glucosidase from Penicillium chrysogenum.
α-glucosidase (EC: 3.2.1.20) was isolated and purified fromPenicillium chrysogenum Thom ATCC 10106 by ammonium sulphate precipitation (75%), DEAE-cellulose and Sephadex G-200. The specific activity was 140 units (U) mg-1 protein. The enzyme expressed a single band using SDS-PAGE and the molecular weight of the enzyme was nearly 43KDa. The optimal pH and temperature were 8 and 40 ºC. The activation energy was 17.94 k J mol-1. The optimal incubation time was 40 min. Glutamine, glutamic acid, cysteine, alanine, phenylalanine, glycine, methionine, asparagine enhanced the enzyme activity and cysteine was the best enhancer. Ho...
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Hamed M El-Shora Source Type: research

Phytochemistry and antibacterial activity of plants extracts compared with two commercial antibiotics against < em > E coli < /em > responsible for avian colibacillosis in Benin
Despite its prominent place in development strategies, poultry breeding faces many constraints, including pathological ones. Among pathologies that affect poultry, colibacillosis is one of the most diseases that are communicable to humans and associated with heavy economic losses. To fight efficiently against avian colibacillosis, the work aimed to evaluate antimicrobial potential evaluation of non-volatile extracts ofEuphorbia hirta andPsidium guajava, as well as the essential oils ofClausena anisata andAeollanthus pubescens extracts and two commercial antibiotics namely tetracolivit and Oxytetracyclin againstEscherichia ...
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Philippe Sessou Source Type: research

Nano-curcumin: A Potent Enhancer of Body Antioxidant System in Diabetic Mice.
Nano preparation of drug to be helpful in targeted delivery, which avoids any unwanted damage of adjacent healthy tissues. Antidiabetic compounds from natural and synthetic sources have been found to successful management of diabetes. Antioxidants are compound that protect cell against the damaging effects of reactive oxygen species (ROS). Curcumin has many beneficial effects against health problems; it has limited use due to its poor bioavailability as concluded by number of its pharmacokinetic studies. Since the aim of this study was to investigate the effectsof curcumin nanoparticles (Nano-curcumin)on antioxidative enzy...
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Nitin Dadasaheb Potphode Source Type: research

Evaluation of hepatoprotective potential of leaf and leaf callus extracts of anisochilus carnosus (l) wall.
The study was carried out to evaluate the hepatoprotective activity of leaf and leaf callus extracts ofAnisochilus carnosus (L) Wall. against alcohol induced toxicity using HepG2 cell line. Leaf explants were cultured on Murashige and Skoog solid medium supplemented with different growth regulators. Prior to the determination of hepatoprotective property leaf and leaf callus extracts were subjected to the toxic dose study. The degree of hepatoprotection of extracts was determined by measuring cell viability percentage by MTT assay. The preliminary phytochemical analysis of leaf and leaf callus was carried out by qualitativ...
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Nissar Ahmad Reshi Source Type: research

Brevifoliol: An Ignored cousin of Taxol
The discovery of paclitaxel, an anticancer agent was a milestone in the path of anticancer drug discovery. After approval from FDA taxol was widely used for cancer treatment. The taxol was isolated from the bark of fully grown taxus plants with is a fatal source, to overcome this problem almost all the species were investigated for the taxol and taxol like molecules.   Brevifoliol is one of the many taxoid isolated from the taxus plants. The significance of brevifoliol was its source which was dried needles of plants including the Himalayan yew tree Taxus wallichiana.Brevifoliol belongs to thelarge group of diterpenoid c...
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Fahad Mohammed Almutairi Source Type: research

A phytopharmacological review on an Arabian medicinal plant: Caralluma flava N.E.Br
Caralluma flava (N.E.Br.) is a medicinal plant which is gaining renowned attention in scientific community due to its potential curative powers. Traditionally, it is used in Arab regions as an anti-diabetic and anti-ulcer. It is also used as an anti-inflammatory, anti-parasitic and anti-pyretic. Due to its pharmacological values, initial biological activities of  C. flava have been carried out recently and some pregnane glycoside molecules have been isolated and identified from its sap. The plant lacks the reports of phytochemical studies and pharmacological activities which support its further investigation and validati...
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Muhammad Adil Raees Source Type: research

Ethanobotanical, phytochemical and pharmacological properties of < em > Zizyphus nummularia < /em > (Burm. F.): A Review
Zizyphus nummularia (Burm. F.), Family: Rhamnaceae, is widely distributed in dry regions of India. It is a bushy weed used as folk medicine. The plant is valued for its nutritional edible fruits. Traditionally, it is used in mental retardation, fever, diarrhea, dysentery. The plant has been evaluated for various pharmacological activities such as anti-inflammatory, anthelmintic, antibacterial, antifertility activity. Present review discusses phytochemistry and pharmacological aspects of the drug. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Babita Aggarwal Source Type: research

Status of research results in chemistry of biologically active substances in Benin
Research on biologically active chemicals extracted from medicinal plants and essential oils from aromatic plants in the West African subregion is booming. Recognition of the clinical, pharmaceutical and economic value of herbal medicines continues to grow despite the growth of the pharmaceutical industry and the continued development of new, more effective synthetic and biological medical products. On the other hand, despite the improvement in food preservation technics, food preservatives nature remains one of the most important issues for public health. Indeed, several synthetic preservatives have been banned in some co...
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Alain Y Koudoro Source Type: research

< em > Solanum tuberosum < /em > L: Botanical, Phytochemical, Pharmacological and Nutritional Significance
Solanum tuberosum commonly known as potato belongs to solanaceae family. The whole part of potato plant including leaves; tuber, peel and juice are used in traditional medicine. A number of pharmacological activities of potato have been reported viz. Antioxidant, anticancer, antiallergy, antibacterial, anti-inflammatory, antiobesity, anti-ulcer activity. Potato contains Phenolic acids, anthocyanin, flavonoids, vitamin B6, vitamin B3, pantothenic acid, potassium, manganese, phosphorous; copper and fibres. The medicinal properties, traditional uses, nutritional value, phytochemical constituents, taxonomy, geographic origin a...
Source: International Journal of Phytomedicine - November 19, 2018 Category: Science Authors: Anjum Sahair R Source Type: research

Nutraceutical Analysis of Marticaria recutita (Chamomile) Dried Leaves and Flower Powder and Comparison between Them
Chamomile is known as German Chamomile (Marticaria recutita) and Roman Chamomile (Chamaemelum nobile) a very famous daisy plant. The work mainly focuses on the nutraceuticals potential of Chamomile leaf and flower of this plant. The nutrient contains of the leaf and flower power was determined by various methods. The phytochemicals screening of the leaf and flower aqueous extract was performed by the different procedure. Leaf of this plant is rich in carbohydrate, protein, fat and also rich in vitamin C, iron, zinc and calcium. Whereas flower is rich in moisture and fiber as compared to leaf. The aqueous extract of leaf of...
Source: International Journal of Phytomedicine - July 10, 2018 Category: Science Authors: Ekta Singh Chauhan Source Type: research

Survey of medicinal plants and patterns of knowledge in district Swabi/ Khyber Pakhtunkhwa, Pakistan
To investigate and document the indigenous knowledge on the medicinal flora of the native communities in Swabi district, Pakistan. A field survey was carried out and data was based on semi-structured interviews, group discussions, and questionnaire from 8 villages. 180 local individual of local communities were interviewed and collected data were analyzed by quantitative and descriptive index. During the survey, 81 species belonging to 45 families were reported. Solanaceae was the leading family with 7 species. Herb (48%) was the dominant plant habit and leaf (24%) was the most preferred used part for indigenous medicine. ...
Source: International Journal of Phytomedicine - July 10, 2018 Category: Science Authors: Abdul Waheed Source Type: research

Effect of Boswellia on Adjuvant Induced Rheumatoid Arthritis in Experimental Animals
Arthritis is the most common systemic connective tissue disease. About 1% of the world ' s population is affected by RA; women are three times more often than men. Onset is most frequent between the ages of 40 and 50 years, but people of any age can be affected. Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks flexible joints. Although the cause of rheumatoid arthritis is unknown, autoimmunity plays an important role in both its chronicity and progression.The new trend of medical treatment of rheumatoid arthritis seeks new drugs with mor...
Source: International Journal of Phytomedicine - July 10, 2018 Category: Science Authors: Omnia Magdy Mohammed Hendawy Source Type: research

To find the efficacy of crude extract from plants on germination of seeds
Germination is the growth of an embryonic plant contained within a seed; it results in the formation of the seedling. The seed of a higher plant is a small package produced in a fruit or cone after the union of male and female sex cells. All fully developed seeds contain an embryo and, in most plant species some store of food reserves, wrapped in a seed coat. Some plants produce varying numbers of seeds that lack embryos, these are called empty seeds, and never germinate. Most seeds go through a period of quiescence where there is no active growth; during this time the seed can be safely transported to a new location and/o...
Source: International Journal of Phytomedicine - July 10, 2018 Category: Science Authors: Ravi Kumar Patil Source Type: research

Anti- α-glucosidase and antiglycation activities of galls from Guiera senegalensis J.F. Gmel (combretaceae)
The hypoglycemic activity ofGuiera senegalensis used in Burkinabe folk medicine has been already reported. The aim of this study was to investigate the invitro antidiabetic activity from galls ofG.senegalensis. The extracts and methanol fractions from galls ofG. senegalensis showed strong α-glucosidase inhibitory activity compared with acarbose. The ethyl acetate fraction from methanol extract (EA/ME) showed potent antiglycation activity in anin vitro assay system. The galls did not show inhibition activity against α-chymotrypsin. The α-glucosidase inhibitory activity along with its antiglycation activity may open a new...
Source: International Journal of Phytomedicine - July 10, 2018 Category: Science Authors: Pierre Alexandre Eric Djifaby SOMBIE Source Type: research

Ethnobotany and preliminary bioactivity investigation on hepatoprotective medicinal plants from the Mouhoun Region of Burkina Faso
An ethnobotanical survey of medicinal plants used to treat hepatitis in the Mouhoun region of Burkina Faso was undertaken. The extracts of the most quoted species were then evaluated for their phytochemistry and their antioxidant activityThe anti-radical activity (by the method of the discoloration of the ABTS cation radical) and that of the antioxidant (by the method of the reduction of the iron ion, FRAP) were evaluated. Then the phenolic content of the aqueous extracts was determined and a correlation was studied between these two parameters.The antioxidant tests showed that the plants counted have a good antioxidant po...
Source: International Journal of Phytomedicine - July 10, 2018 Category: Science Authors: Jotham Yhi-p ênê N ' DO Source Type: research