International Journal of Phytomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Anticancer and Antioxidant activity of Tephrosia calophylla against cancer cell lines
Conclusions: The present study shows anticancer potentials of methanol extract ofTephrosia calophyllaagainst MCF 7, HCT-116 and A-549 cell lines.   (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - August 29, 2019 Category: Science Authors: Ramesh C Source Type: research

Synthesis and Characterization of Novel Rutin Derivatives with Potential Antioxidant Properties
This study showed that Rutin and its derivatives exhibited antioxidant activity in all tests and could be considered as a source of natural and synthetic antioxidants.   (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - August 29, 2019 Category: Science Authors: Mohammed Abdalla Hussein Source Type: research

A study on ftir, antimicrobial, antioxidant and hypogycaemic effect of diospyros kaki and citrullus colocynthis
Phytochemical, FTIR screening, Hypoglycemic study, antibacterial, antifungal and antioxidant activity ofCitrullus colocynthis andD. kaki fruit were studied. The interest of this study is to evaluate traditional herbal usage to treat many diseases around the sultanate of Oman locally. The functional groups that they contain are (O-H) Phenol, (C-H) Alkyl, (N-H) Amine and (C=C) Alkenyl groups corresponds to their biological phytoconstituents responsible for the medicinal properties. The antibacterial and antifungal activities revealed that all parts of tested samples shown good antimicrobial properties. While leaf ofC. colocy...
Source: International Journal of Phytomedicine - August 29, 2019 Category: Science Authors: Hemadri Reddy Salla Source Type: research

In vitro antioxidant, 𝛼-amylase and 𝛼-glucosidase activities of methanol extracts from three Momordica species
AbstractAntioxidant based drug preparations are used in the prevention and management of complex diseases which include atherosclerosis, stroke, diabetes, alzheimer ’s disease and cancer. Diabetes mellitus is a metabolic disorder of glucose metabolism. The management of blood glucose level is the hallmark in the treatment of this ailment, which may be achieved through the use of oral hypoglycemic drugs such as biguanides, insulin secretagogues, and 𝛼-amyla se and glucosidase inhibitors. Although several biological activities had been reported for MomordicafoetidaandMomordicacharantia; it appears there is limited info...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Olubunmi Adenike Akinwunmi Source Type: research

Ethnobotanic survey of the galactagogue plants used by Brong and Koulango, two indigenous peoples in Gontougo region/C ôte d’Ivoire
This study aims to inventory plants and traditional medicinal recipes used by the population of Tanda (Gontougo region, C ôte d’Ivoire) to boost milk production in women.Using a questionnaire, the methods consisted in carrying out a survey near the traditional medicine actors of 15 localities. Among 47 actors of traditional medicine aged from 34 to 80 years investigated, 70.21 % were women. These women had more knowledge on the galactagogue plants than the men (29.79 % of the actors). They were represented by matrons, specialists in lactation, healers and saleswomen of medicinal plants. Among about fifteen listed galact...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Bruno Koffi Koko Source Type: research

In vitro antioxidant, α-amylase and α-glucosidase activities of methanol extracts from three Momordica species
AbstractAntioxidant based drug preparations are used in the prevention and management of complex diseases which include atherosclerosis, stroke, diabetes, alzheimer ’s disease and cancer. Diabetes mellitus is a metabolic disorder of glucose metabolism. The management of blood glucose level is the hallmark in the treatment of this ailment, which may be achieved through the use of oral hypoglycemic drugs such as biguanides, insulin secretagogues, and 𝛼-amyla se and glucosidase inhibitors. Although several biological activities had been reported for MomordicafoetidaandMomordicacharantia; it appears there is limited info...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Oubunmi Adenike Akinwunmi Source Type: research

Evaluation of in vitro Cholesterol esterase inhibitory and in vivo Anti-hyperlipidemic activity of aqueous extract of Plukenetia conophora Mull. Arg. (Euphorbiaceae)
Hyperlipidemia is a condition of abnormally high lipids levels in the blood which has been ranked as one of the greatest risk factors contributing to prevalence and severity of coronary heart disease. The available antihyperlipidemic drugs have been associated with some side effects however, herbal management of hyperlipidemia are relatively safe, cheap and readily available.P. conophora is an edible plant consumed in Nigeria as snack and speculated to have beneficial effect on blood lipid profile. The present study evaluates anti-hyperlipidemic effect of aqueous extract of cookedP.  conophoranut usingin vivo andin vitro ...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Glory Oluremilekun Ajayi Source Type: research

Preliminary phytochemical screening and Evaluation of hepatoprotective activity of ethanolic extract of whole plant of Evolvulus alsinoides using CCl4 induced model in experimental animals
Present study was conducted to evaluate the preliminary phytochemical screening and hepatoprotective activity of whole plant ofEvolvulus alsinoides. The whole plant was defatted with petroleum ether and then extracted with 90 % ethanol. The phytochemical screening was done for ethanol extract using standard procedures. Acute toxicity was done using OECD 423 guidelines and the extract was found to be practically non-toxic upto a dose of 1500mg/kg b.w. when given orally. Hepatoprotective activity was evaluated using Carbon tetra chloride induced model in rats. In CCl4 induced mothod of 90% Ethanolic extract of whole plant of...
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Gomathi Periasamy Source Type: research

Chemical Composition of the Essential oil of The Leaves of Pimenta diocia (L.) Merr. & amp; Pimenta racemosa (Mill.) cultivated in Egypt and Evaluation of Their in-vitro Antioxidant and Antidiabetic Activities
Conclusion: the present study clearly identified the Egyptian chemotype ofPimenta diocia (L.) Merr. andPimenta racemosa (Mill.) leaves essential oil, it also displayed safe and promising antidiabetic and antioxidant properties. Therefore the essential oil of both species can be utilized as a natural antioxidant and antidiabetic as well as health benefits. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Mohammed Abdalla Hussein Source Type: research

Appraisal of the Constituent Plant Materials in a Ghanaian Antifungal Herbal Product; An in vitro Interactive Combination Analysis and a Pilot Clinical Study to Determine Efficacy.
In conclusion, the original formulation of the product may be preferred because of the shorter duration of treatment which reduces the risk of harms and cost of treatment. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Kwesi Prah Thomford Source Type: research

Phytochemical and antibacterial potentials of Tecoma stans and Costus afer
Phytochemical composition and antibacterial potential of ethanolic extract of leaves/roots ofTecoma stans and leaves ofCostus afer evaluated were collected at Malabo Campus, University of Calabar, Calabar and from Eman-Uruan local government area, Akwa Ibom, Nigeria respectively. Fresh leaves of both plants and roots ofTecoma stans collected were washed, dried on laboratory surface and milled into powder. They were separately extracted in 80% ethanol and the extracts concentrated in vacuo at 37-40oC to obtain semi solid dark green and brown concentrates respectively used for the evaluations. Phytochemical composition was d...
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Ini Patrick Ekpe Source Type: research

Induction, immobilization, modification and natural inhibitors of α-glucosidase from Penicillum chrysogenum
α-glucosidase (EC: 3.2.1.20) was isolated fromPenicillum chrysogenum. The enzyme was enhanced by plant growth regulators such as gibberellic acid (GA3), benzylaminopurine (BAP) and kinetin. Dansyl chloride inhibited the enzyme at 1, 2, 3, 4 and 5 mM with T0.567, 52.2, 34.4 and 23.3 min, respectively. The substrate offered partial protection for the enzyme against dansyl chloride inhibition. The enzyme was activated by Ca2+ and Mg2+. However, Pb2+, Cd2+, Zn2+, Ni2+ and Hg2+ inhibitedα-glucosidase activity. The enzyme was immobilized on Ca alginate and the optimal concentration for 3% w/v. The optimal concentration of CaCl...
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Hamed M. El-Shora Source Type: research

Synergistic Effects of Andrographolide on DNA Damage Repair Mechanism and Apoptosis in Breast Cancer Cells
Breast cancer is the second leading cause of cancer deaths in women. Several drugs including cisplatin and carboplatin have shown tremendous effectivity in reducing cancer; however development of drug resistance by breast cancer cells to overcome cytotoxic insults and recurrence of the disease is a major concern at the moment. Andrographolide is a diterpenoid with a potent anti-inflammatory and anti tumor activity and it ’s usage in combination therapy would be ideal as it is proven for it’s apoptotic capability in varied number of cells. Antiproliferative and apoptotic activity of andrographolide in triple negative MD...
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Venkateshwari Ananthapur Source Type: research

Anticancer and Anti-metastatic Effects of Supercritical Extracts of Hops (Humulus lupulus L.) and Mango ginger (Curcuma amada Roxb.) in Human Glioblastoma
Glioblastoma is one of the most aggressive, lethal and incurable primary brain tumors with a dismal prognosis in humans. Mango ginger (Curcuma amada) and hops(Humulus lupulus) are two botanicals containing phytochemicals with potential anticancer effects. We have investigated the anticancer and antimetastatic properties of supercritical CO2 extract of mango ginger (CA) and ethanol extract of hops (HL) in the U-87MG human glioblastoma cell line. Both CA and HL individually demonstrate strong cytotoxicity against glioblastoma cells. CompuSyn analysis of cytotoxicity data confirms that CA and HL are synergistic for cytotoxici...
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: Cheppail Ramachandran Source Type: research

Phenolic content and antioxidant activity of young and mature mango (Mangifera indica) and avocado (Persea americana) leave extracts
This study was carried out to evaluate the phenolic content and antioxidant activity of young and mature avocado (Persea americana) and mango leaves (Mangifera indica). Different extracts were prepared by maceration in methanol, ethanol, cold and hot water. The phenolic content of the extracts was determined using the Folic-Ciocalteu Method. A total of three antioxidant tests were done on the extracts: the 2, 2-diphenyl-1-picrylhydrazyl test (DPPH test), the Ferric reducing antioxidant power and the Hydroxyl radical scavenging activity. Results of these investigations generally showed that the mature leaves of mango and yo...
Source: International Journal of Phytomedicine - January 7, 2019 Category: Science Authors: F élicité Kingne Kingne Source Type: research