International Journal of Phytomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Cranberry Extract as a Supplemented Food in Treatment of Oxidative Stress and Breast Cancer Induced by N-methyl-N-nitrosourea in Female Virgin Rats
Breast cancer is the most common cancer and a major cause of death in women. The present study was designed to evaluate the antioxidant and anticancer potential of cranberry extract against N-methyl-N-nitrosourea (MNU) induced mammary carcinoma in rats. The tumor was induced in Female virgin rats of age 50 days by single dose of MNU (50mg/kg.b.w i.p.). After 85 days; all rats developed at least one tumor. Animals were treated with cranberry extract (400 and 600 mg/kg.b.w.orally) and tamoxifen (2mg/kg.b.w.  i.p) for 4 weeks (from day 86 to day 113). MNU treatment resulted in a significant decrease (p < 0.05) in blood he...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Sylvia A. Boshra Source Type: research

Synergistic effect of ethno medicinal plants against biofilm forming Streptococcus pyogenes isolated from upper respiratory tract infection
The present study is an attempt to determine the synergistic anti-biofilm efficacy of three Indian medicinal plants namely Ocimum tenuiflorum, Plectranthus amboinicus, and Tylophora indica (OPT) against the biofilm forming Streptococcus pyogenes of upper respiratory tract infection. The leaves were collected and subjected to methanol extraction. The combined extract (OPT) was subjected to preliminary phytochemical and GC-MS analysis. About, ten isolates of S. pyogenes were obtained from the throat swabs samples and studied for biofilm forming potential. The strong biofilm forming isolates were subjected to Minimal Inhibito...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: MANIMEKALAI KANAGARAJAN Source Type: research

The phytochemical investigation and biological activity of Nepeta clarkei
The present study is aimed at the isolation and identification of the compounds responsible for the bioactive behavior of Nepeta clarkei (Hook. f). The crude extract and its various sub-fractions obtained from N. clarkei Hook. f. (chloroform (NCC), n-hexane (NCH), ethyl acetate (NCE), and aqueous (NCW)) along with methanolic extract were screened for anti-cancer activity. Only NCH and NCC fractions suppressed the cancer cell lines (HT29 and HCT116) to less than 20% and were screened for a range of other biological activities (antiglycation, phytotoxicity, antiplattelt, insecticidal and antimicrobial) in vitro. The chlorofo...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Najeeb Rehman Source Type: research

Antibacterial Potency and Phytochemical Screening of the Bark of Terminalia catappa Against some Clinical Isolates
This study indicates that the extracts were efficacious and can be used for the management of diseases caused by the tested organisms. Results obtained support the use of this plant as use in traditional medicine and support that the plant extracts possess compounds with good antimicrobial properties that can be used as antimicrobial agents in the search for new antimicrobial drugs. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Majekodunmi Racheal Adedayo Source Type: research

Effects of Methanolic Leaf Extract of Momordica charantia on Testicular Marker Enzymes and Gonadotrophic Hormones in Cadmium-induced Gonadotoxic Rats
To investigate pre-treatment effects of Momordica charantia (MC) leaf against cadmium-induced gonad toxicity in male rats. Thirty male wistar rats weighing 200-300g were randomly divided into three groups (A, B and C) of ten rats each. Group A received normal saline orally. Group B was treated with 2.5mg/kg bwt cadmium subcutaneously while group C were pre-administered with 300mg/kg bwt MC extract orally before treating with subcutaneous cadmium 2.5 mg/kg bwt. Animals were treated every other day for six weeks. Serum testosterone, luteinizing hormone (LH) and follicle stimulating hormone (FSH) were evaluated. Testis alkali...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Bamidele S. Ajilore Source Type: research

The relevance of Asteraceae family plants in most of the neuropsychiatric disorders treatment
Many of the traditional medicinal plants belong to one of the largest plant families: the Asteraceae family. These plants are widely used in alternative medicine due to their effects on the nervous system, being studied both on cellular and animal models. In this way, medicinal plants are preferred in drug therapy research due to the wide population interest. The Asteraceae plants phytochemical composition is mainly consisted in cholinergic, dopaminergic or serotonergic molecules which are involved in the pathophysiology of the neuropsychiatric disorders such as Alzheimer’s disease, Parkinson’s disease, schizophrenia, ...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: SAMSON GUENNE Source Type: research

A detailed overview of medicinal plants having hypoglycemic activity
Diabetes mellitus represents a spectrum of metabolic disorder, which has become one of the major public health concerns worldwide. Diabetes mellitus has emerged as a third leading killer after cancer and cardiovascular/cerebrovascular diseases and India has a distinction of having largest number of diabetics in world second to China. Herbal medicine for treating chronic diseases, especially diabetes has gained an exponential growth in the last few years and both developing and developed countries are adopting herbal drugs for treatment of diabetes mellitus. The World Health Organization (WHO) has listed 21,000 plants, whic...
Source: International Journal of Phytomedicine - June 18, 2016 Category: Science Authors: Sandra Celine Source Type: research

Toxicological evaluation of Diakure, an antidiabetic polyherbal formulation
Context and Purpose of the Study: DiaKure is a hypoglycemic polyherbal formulation prepared indigenously based on knowledge of traditional medical practitioners, which contains polyherbal mixture of Vetiveria zizanioides (root), Hemidesmus indicus (rhizome), Strychnos potatorum (seed), Salacia reticulata (bark), Holarhena antidysenterica (seed), Cassia auriculata (bark), Trigonella graecum (seed) and Acacia catechu (bark) and each individual herb has scientific background in treating diabetes by the folk medical practitioners in various communities of India. The main aim of present study is to conduct an acute and sub-acut...
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: Shawn Tomy Source Type: research

Redox properties of a standardized extract of Chenopodium quinoa Willd fruit pericarp modify rat liver GST activities
Research of antioxidant properties of herbal thiol compounds is scarce. The main non-enzymatic antioxidant compounds in animal cell are GSH and cysteine. Therefore, in this work, we studied the redox effects of a Chenopodium quinoa Willd (Quinoa) coats extract previously titrated in its polyphenol and thiol compounds. The effects of quinoa extract on rat liver cytosolic and microsomal GSH-transferase was tested. The catalytic active form of this enzyme is its disulphide dimer, and then its reduction provokes its inactivation. Quinoa extract inhibited both enzymatic activities in a concentration-dependent manner. The reduci...
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: María Eugenia Letelier Source Type: research

In vivo neurological assessment of sedative hypnotic effect of Coriandrum sativum L. seeds in mice.
Conclusion: from present study finding it is found that seeds of Coriandrum sativum L. potentiate the sedative hypnotic efficacy in mice.  (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: Abdulrahman M Alshahrani Source Type: research

Chemical composition, antioxidant and antibacterial activities of extracts obtained from the roots bark of Arbutus andrachne L. a Lebanese tree.
Context and purpose of the study: The leaves, fruits, barks and roots of Arbutus andrachne L (A. andrachne), have been adopted to have high therapeutic value resulting from the presence of antioxidant compounds such as flavonoids, phenolic and tannins. In the present work, three extracts obtained from A. andrachne roots bark were evaluated for their antioxidant and antibacterial activities .The total phenolic content, flavonoid, condensed tannins and anthocyanins were determined in order to correlate them with the antioxidant activity of extracts.Main findings: The highest amounts of phenolic and tannins were found in the ...
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: Emna Abidi Source Type: research

Effect of an herbal extract of Sideritis scardica and B-vitamins on cognitive performance under stress: a pilot study
Chronic stress can impair cognitive functions including learning and memory. The current study investigated the reduction of (mental) stress and improvement of stress tolerance in 64 healthy men and women after six weeks intake of a dietary supplement containing an extract of Sideritis scardica and selected B-vitamins.Mental performance and visual attention were measured by Trail-Making Test (TMT) and Colour-Word-Test (CWT) before/after an acute stress stimulus (noise, CW-Interference).TMT improved upon product intake. The CWT reaction time accelerated upon product intake in situations of CW-Congruence (overall) (p=0.014),...
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: Isabel Behrendt Source Type: research

Antimicrobial Activity of Some Trigonella Species
The genus Trigonella includes many medicinal and aromatic plant species used in traditional as well as veterinary medicines for different diseases, alone or in combination with other remedies. The crude methanol extracts of 15 Trigonella species were assayed for antimicrobial activity against four medicinally important multidrug resistant clinical isolates, five plant pathogenic bacteria and five fungi.Three species showed a broad spectrum of antibacterial activity inhibiting all the test bacteria. Acidified ethanolic extract of the most promising species, T. suavissima was purified by column chromatography. Characterizati...
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: Rakhee Shyam Dangi Source Type: research

Velvet bean roots stimulates humoral and cell mediated immunity and offers protection against Cyclophosphamide induced myelosuppression.
The objective of the study was to investigate the immunomodulatory activity of roots of Mucuna pruriens on cellular and humoral immunity.  Extraction and phytochemical screening of the roots were performed using standard methods, HPTLC fingerprinting profiles of the methanol extract were developed on CAMAG system, to resolve components, Quantification of β-Sitosterol  was done by validated HPTLC method. Immunomodulatory activity of the extract was assessed by Cyclophosphamide-induced myelosuppression assay, Macrophage phagocytosis by Carbon clearance method, Humoral antibody response and Delayed type hypersensitivity re...
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: Krishna Murthy Source Type: research

Study of Phytochemical screening,Total Phenolic and Flavonoid Content and Antioxidant Activity of Pulicaria glutinosa growing in Saudi Arabia
Phytochemical screening of P. glutinosa extracts revealed the presence of alkaloids, terpenes, sponins, flavonids, anthraquinone and glycosides. Quantitative determination of total phenolics, total flavonoids, and various in vitro antioxidant activities (DPPH, ABTS metal chelation effect in the Fe2+-ferrozin test system) of the various extracts from the P. glutinosa was carried out. Phenol and flavonoid content of the extract were measured by folin ciocalteu and AlCl3 assays. The Phenol and flavonoid content of the extracts varied between 18.33 – 199.44 mg/g and 14.64 – 164.73 mg/g, respectively. The results showed tha...
Source: International Journal of Phytomedicine - March 27, 2016 Category: Science Authors: Jehan Yahya Al-humaidi Source Type: research