Aloe-emodin triggers ROS and Ca 2+ production and decreases the levels of mitochondrial membrane potential of human brain capillary endothelial cells

Conclusions: Our results collectively indicat e that AE inhibits proliferation of human brain microvascular cells via a mechanism involving ROS generation, disruption of Ca 2+ homeostasis and mitochondrial damage.

Source: International Journal of Phytomedicine - September 2, 2017 Category: Science Authors: Ivanka Dimova Source Type: research