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Diseases of the Esophagus,Volume 29, Issue 8, Page 950-958, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - February 2, 2016 Category: Gastroenterology Source Type: research
Long noncoding RNA, tissue differentiation ‐inducing nonprotein coding RNA is upregulated and promotes development of esophageal squamous cell carcinoma
Summary
Esophageal squamous cell carcinoma (ESCC) is one of the major causes of cancer death worldwide, especially in Eastern Asia. Due to the poor prognosis, it is necessary to further dissect the underlying mechanisms and explore therapeutic targets of ESCC. Recently, studies show that long noncoding RNAs (lncRNAs) have critical roles in diverse biological processes, including tumorigenesis. Increasing evidence indicates that some lncRNAs are widely involved in the development and progression of ESCC, such as HOTAIR, SPRY4‐IT1 and POU3F3. An emerging lncRNA, tissue differentiation‐inducing nonprotein coding RNA (TINC...
Source: Diseases of the Esophagus - February 1, 2016 Category: Gastroenterology Authors: Y. Xu, M. Qiu, Y. Chen, J. Wang, W. Xia, Q. Mao, L. Yang, M. Li, F. Jiang, L. Xu, R. Yin Tags: Original Article Source Type: research
Thermogenesis induced by amino acid administration prevents intraoperative hypothermia and reduces postoperative infectious complications after thoracoscopic esophagectomy
Summary
Minimally invasive thoracoscopic esophagectomy has potential advantages in minimizing the impairment of respiratory function and reducing surgical stress. However, thoracoscopic esophagectomy occasionally results in anesthesia‐induced hypothermia, particularly in cases involving artificial pneumothorax with CO2. Thermogenesis induced by amino acid administration has been reported during anesthesia. Here, we tested the efficacy of amino acid treatment for the prevention of hypothermia, and we investigated the potential of this treatment to reduce postoperative infectious complications after thoracoscopic esophagec...
Source: Diseases of the Esophagus - February 1, 2016 Category: Gastroenterology Authors: T. Fujita, N. Okada, J. Kanamori, T. Sato, S. Mayanagi, K. Torigoe, A. Oshita, H. Yamamoto, H. Daiko Tags: Original Article Source Type: research
Interference with daily activities and major adverse events during esophageal pH monitoring with bravo wireless capsule versus conventional intranasal catheter: a systematic review of randomized controlled trials
Summary
For three decades, ambulatory 24‐hour intranasal pH monitoring has been the established gold standard for detecting acid reflux in patients with refractory gastroesophageal reflux disease. However, device‐associated adverse events and unpleasant experiences, reported by patients during pH monitoring have led to the invention of more convenient pH monitors such as Bravo wireless capsule. To compare the interference with daily activities and major adverse events during pH monitoring with Bravo wireless capsule (Bravo) versus conventional intranasal catheter (catheter), PubMed, Cochrane Library, Clinical Trials.go...
Source: Diseases of the Esophagus - February 1, 2016 Category: Gastroenterology Authors: A. Iluyomade, A. Olowoyeye, O. Fadahunsi, L. Thomas, C. N. Libend, K. Ragunathan, J. Fenster, S. Vignesh Tags: Review Source Type: research
The intrapapillary capillary loop (IPCL) changes in superficial esophageal lesions
In conclusion, the results of this observation showed the Japan Esophageal Society classification of IPCL would help endoscopists to diagnose the type and the invasion depth of lesion in esophagus, and decide the treatment strategy. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - January 31, 2016 Category: Gastroenterology Authors: H.‐L. Wu, B.‐X. Guan, B. Liu, H.‐J. Wang, M.‐B. Zhang, G.‐C. Li, K.‐X. Zhu, C.‐J. Zhou, J.‐Q. Guo Tags: Original Article Source Type: research
Is rigid endoscopy necessary with childhood corrosive ingestion? a retrospective comparative analysis of 458 cases
Summary
The aim of this study was to determine the necessity of endoscopy in cases in which a corrosive substance was ingested and to find a practical way to avoid unnecessary endoscopies for similar cases in the future. The clinical records of 458 hospitalized cases with clinical histories of corrosive substance ingestion between January 2007 and December 2013 were retrospectively reviewed. The demographics of the cases, the ingested substances, and the rigid endoscopy findings were evaluated. The three most commonly ingested corrosive agents were household bleach (22.9%), household degreaser (15.9%), and drain cleaner (1...
Source: Diseases of the Esophagus - January 29, 2016 Category: Gastroenterology Authors: O. Bosnalı, S. Moralıoğlu, A. Celayir, O. Z. Pektaş Tags: Original Article Source Type: research
Polymorphisms of the FOXF1 and MHC locus genes in individuals undergoing esophageal acid reflux assessments
This study evaluated whether these two polymorphisms are associated with gastroesphageal acid reflux as measured by 24‐hour pH testing. Patients with acid reflux symptoms referred for esophageal manometry and 24‐hour pH monitoring at University Health Network (Toronto, ON) were enrolled. DNA extracted from blood was genotyped using a Taqman Polymerase Chain Reaction (PCR) assay. DeMeester scores of ≥14.7 or prior evidence of reflux esophagitis on endoscopy defined individuals with esophageal acid reflux. Logistic regression analysis, adjusted for clinical risk factors, was used to calculate odds ratios with 95% confi...
Source: Diseases of the Esophagus - January 29, 2016 Category: Gastroenterology Authors: C. Lam, W. F. Liu, R. D. Bel, K. Chan, L. Miller, M. C. Brown, Z. Chen, D. Cheng, D. Patel, W. Xu, G. E. Darling, G. Liu Tags: Original Article Source Type: research
Dronabinol increases pain threshold in patients with functional chest pain: a pilot double‐blind placebo‐controlled trial
Summary
Noncardiac chest pain is associated with poor quality of life and high care expenditure. The majority of noncardiac chest pain is either gastresophageal reflux disease related or due to esophageal motility disorders, and the rest are considered functional chest pain (FCP) due to central and peripheral hypersensitivity. Current treatment of FCP improves 40–50% of patients. Cannabinoid receptors 1 (CB1) and 2 (CB2) modulate release of neurotransmitters; CB1 is located in the esophageal epithelium and reduces excitatory enteric transmission and potentially could reduce esophageal hypersensitivity. We performed a pro...
Source: Diseases of the Esophagus - January 29, 2016 Category: Gastroenterology Authors: Z. Malik, L. Bayman, J. Valestin, A. Rizvi‐Toner, S. Hashmi, R. Schey Tags: Original Article Source Type: research
Most children with eosinophilic esophagitis have a favorable outcome as young adults
Summary
The disease progression of eosinophilic esophagitis (EoE) from childhood into adulthood is unclear. To determine the clinical outcome of patients who were diagnosed with EoE as children, and who now are young adults. Children (<18 years old) diagnosed with EoE were enrolled in a prospective registry on demographics, presenting symptoms, and endoscopic/histologic findings. Subjects who now are adults (≥18 years old) were identified, and a structured telephone interview was conducted to obtain follow‐up data on symptom prevalence (dysphagia to solids and liquids, nausea/vomiting, abdominal pain, and heartburn/...
Source: Diseases of the Esophagus - January 29, 2016 Category: Gastroenterology Authors: M. Bohm, J. W. Jacobs, A. Gupta, S. Gupta, J. M. Wo Tags: Original Article Source Type: research
Prevalence rate and clinical characteristics of esophageal ectopic sebaceous glands in asymptomatic health screen examinees
In conclusion, esophageal ectopic sebaceous glands are present in 0.05% of asymptomatic subjects. This lesion is thought to be benign and is not related to clinical symptoms. Therefore, esophageal ectopic sebaceous glands do not require further treatment or follow‐up, which makes endoscopists free from active efforts for differential diagnosis with other malignant diseases. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - January 29, 2016 Category: Gastroenterology Authors: Areum Park, Jung‐Hyun Lee, Ayoung Park, Young‐Hwan Jung, Hyung‐Jun Chu, Sang‐Su Bae, Jeong‐Kwon Kim, Won‐Yong Kim, Byung‐Kook Kim Tags: Original Article Source Type: research
Dronabinol increases pain threshold in patients with functional chest pain: a pilot double ‐blind placebo‐controlled trial
Summary
Noncardiac chest pain is associated with poor quality of life and high care expenditure. The majority of noncardiac chest pain is either gastresophageal reflux disease related or due to esophageal motility disorders, and the rest are considered functional chest pain (FCP) due to central and peripheral hypersensitivity. Current treatment of FCP improves 40–50% of patients. Cannabinoid receptors 1 (CB1) and 2 (CB2) modulate release of neurotransmitters; CB1 is located in the esophageal epithelium and reduces excitatory enteric transmission and potentially could reduce esophageal hypersensitivity. We performed a pro...
Source: Diseases of the Esophagus - January 28, 2016 Category: Gastroenterology Authors: Z. Malik, L. Bayman, J. Valestin, A. Rizvi ‐Toner, S. Hashmi, R. Schey Tags: Original Article Source Type: research
Simultaneous thoraco ‐laparoscopic repair of giant hiatal hernias: an alternative approach
Summary
Laparoscopic repair of giant hiatal hernias with intrathoracic displacement of organs is recommended to relieve troublesome symptoms in patients. During this procedure, incomplete excision of the hernia sac from the mediastinum and omission of creating a ‘non‐tension‐free position’ of the cardio‐esophageal junction into the abdominal cavity are associated with hiatal hernia recurrence. Giant hiatal hernias therefore often require a thoracotomy or thoracoscopy, to free dense adhesions higher up the chest. These procedures may increase the risk of perioperative morbidity due to lengthy operating times. We d...
Source: Diseases of the Esophagus - January 28, 2016 Category: Gastroenterology Authors: W. J. Derksen, J. E. Oor, A. Yilmaz, E. J. Hazebroek Tags: Original Article Source Type: research
Issue Information
(Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - January 15, 2016 Category: Gastroenterology Tags: Issue Information Source Type: research
Novel stent in the palliation of malignant esophageal strictures: a retrospective study
Summary
The placement of metal stents is often used as a palliative treatment for malignant esophageal stenosis. We designed a novel stent that has been used clinically since 2011, and we therefore performed a retrospective study to compare the therapeutic effects of this novel metal stent to a conventional partially covered metal stent in patients with malignant esophageal strictures. The records of 201 consecutive patients who underwent placement of either the conventional partially covered metal stents (Group A, n = 92) or the new metal stents (Group B, n = 109) in the Endoscopy Center of General Hospital of Chengdu Mil...
Source: Diseases of the Esophagus - January 3, 2016 Category: Gastroenterology Authors: H. Chen, Z. Ni, D. Jing, L. He, L. Qiao, L. Liu, X. Wei, M. Jiang, S. Tang, H. Xu Tags: Original Article Source Type: research
External validation of a risk score in the prediction of the mortality after esophagectomy for cancer
This study was designed as an external evaluation of the Steyerberg score in the prediction of different categories of postoperative mortality after esophagectomy on a large nationwide database of thoracic surgeons. Data collection was obtained from the Epithor national database encompassing the majority of thoracic procedures performed in France. We retrospectively compared the predicted to the observed postoperative 30‐day (30DM), 90‐day (90DM) and in‐hospital mortality (IHM) rate in each decile of equal patient. Patients included in the study were operated for an esophageal cancer and Gastroesophageal junction (GE...
Source: Diseases of the Esophagus - January 3, 2016 Category: Gastroenterology Authors: X. B. D'Journo, J. Berbis, J. Jougon, P.‐Y. Brichon, J. Mouroux, O. Tiffet, A. Bernard, F. Dominicis, G. Massard, P. E. Falcoz, P. Thomas, M. Dahan Tags: Original Article Source Type: research
