How to measure disease activity in eosinophilic esophagitis
Diseases of the Esophagus,Volume 29, Issue 8, Page 959-966, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Source Type: research
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Diseases of the Esophagus,Volume 29, Issue 8, Page 983-991, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Source Type: research
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Diseases of the Esophagus,Volume 29, Issue 8, Page 1172-1172, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Source Type: research
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Diseases of the Esophagus,Volume 29, Issue 8, Page 1164-1166, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Source Type: research
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Diseases of the Esophagus,Volume 29, Issue 8, Page 967-970, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Source Type: research
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Diseases of the Esophagus,Volume 29, Issue 8, Page 959-966, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Source Type: research
Combining different therapeutic interventions in eosinophilic esophagitis may lead to unreplicable and misleading results
(Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Authors: J. Molina‐Infante, A. J. Lucendo Tags: Letter to the Editor Source Type: research
Randomized controlled trial comparing esophageal dilation to no dilation among adults with esophageal eosinophilia and dysphagia
Summary
The role of esophageal dilation in patients with esophageal eosinophilia with dysphagia remains unknown. The practice of dilation is currently based on center preferences and expert opinion. The aim of this study is to determine if, and to what extent, dysphagia improves in response to initial esophageal dilation followed by standard medical therapies. We conducted a randomized, blinded, controlled trial evaluating adult patients with dysphagia and newly diagnosed esophageal eosinophilia from 2008 to 2013. Patients were randomized to dilation or no dilation at time of endoscopy and blinded to dilation status. Endos...
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Authors: R. T. Kavitt, F. Ates, J. C. Slaughter, T. Higginbotham, B. D. Shepherd, E. L. Sumner, M. F. Vaezi Tags: Original Article Source Type: research
Short‐term and long‐term effect of diaphragm biofeedback training in gastroesophageal reflux disease: an open‐label, pilot, randomized trial
In conclusion, long‐term DBT could reduce acid suppression usage by enhancing the anti‐reflux barrier, providing a non‐pharmacological maintenance therapy and reducing medical costs for patients with GERD. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Authors: X. Sun, W. Shang, Z. Wang, X. Liu, X. Fang, M. Ke Tags: Original Article Source Type: research
How to measure disease activity in eosinophilic esophagitis
Summary
Activity of Eosinophilic Esophagitis (EoE) can be measured by patient reported outcomes (symptoms and quality of life) and clinician‐reported outcomes (endoscopic, histologic, or biochemical alterations). Over the last years efforts have been underway to develop and validate instruments to assess EoE activity in the different domains. Such instruments are urgently needed to standardize the language of EoE activity assessment and, in so doing, to facilitate communication among various stakeholders. Such standardization will ultimately allow EoE researchers to define meaningful endpoints for use in clinical trials ...
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Authors: A. Schoepfer, E. Safroneeva, A. Straumann Tags: Review Article Source Type: research
High‐resolution manometry findings in symptomatic post‐Nissen fundoplication patients with normal endoscopic configuration
Summary
The aim of this study was to investigate high‐resolution manometry (HRM) findings in symptomatic post‐fundoplication patients with normal endoscopic configuration. A retrospective review of a prospectively maintained database was conducted to identify patients who underwent evaluation with HRM and endoscopy for symptom evaluation after previous fundoplication. Study period extends from September 2008 to December 2012. Only patients with complete 360° fundoplication (Nissen) were included, and patients with partial fundoplication were excluded. Patients with endoscopic abnormality or patients who underwent Coll...
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Authors: S. R. Yamamoto, S. Akimoto, M. Hoshino, S. K. Mittal Tags: Original Article Source Type: research
Single‐center prospective study of Plummer–Vinson syndrome
Summary
Post‐cricoid web is an uncommon cause for dysphagia and is most frequently reported in middle‐aged women. Triad of web, iron deficiency anemia (IDA), and dysphagia is known as Plummer–Vinson syndrome (PVS). Literature on PVS is very limited. Here we report the first prospective study of PVS with predefined diagnostic criteria and management plan. Adults with dysphagia or those incidentally found to have esophageal web were prospectively enrolled between July 2011 and June 2013. Participants were evaluated with hemogram, barium swallow, and esophagogastroduodenoscopy. PVS was diagnosed if a person had IDA and ...
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Authors: A. Goel, C. P. Lakshmi, S. S. Bakshi, N. Soni, S. Koshy Tags: Original Article Source Type: research
Thoracolaparoscopic dissection of esophageal lymph nodes without esophagectomy is feasible in human cadavers and safe in a porcine survival study
Summary
High‐risk early esophageal adenocarcinoma (i.e. submucosal invasion >500 nm, poor differentiation, and/or presence of lymphovascular invasion) is currently treated with esophagectomy with lymph node (LN) dissection given the high rates of LN metastases. However, esophagectomy is associated with substantial morbidity and mortality. Endoscopic radical resection followed by thoracolaparoscopic LN dissection without concomitant esophagectomy could be an alternative. The study aim was to evaluate the feasibility and safety of thoracolaparoscopic dissection of esophageal LNs in a preclinical setting. (i) In human ...
Source: Diseases of the Esophagus - July 30, 2015 Category: Gastroenterology Authors: H. Künzli, M. Berge Henegouwen, S. Gisbertz, C. Seldenrijk, K. Kuijpers, J. Bergman, M. Wiezer, B. Weusten Tags: Original Article Source Type: research
High ‐resolution manometry findings in symptomatic post‐Nissen fundoplication patients with normal endoscopic configuration
Summary
The aim of this study was to investigate high‐resolution manometry (HRM) findings in symptomatic post‐fundoplication patients with normal endoscopic configuration. A retrospective review of a prospectively maintained database was conducted to identify patients who underwent evaluation with HRM and endoscopy for symptom evaluation after previous fundoplication. Study period extends from September 2008 to December 2012. Only patients with complete 360° fundoplication (Nissen) were included, and patients with partial fundoplication were excluded. Patients with endoscopic abnormality or patients who underwent Coll...
Source: Diseases of the Esophagus - July 29, 2015 Category: Gastroenterology Authors: S. R. Yamamoto, S. Akimoto, M. Hoshino, S. K. Mittal Tags: Benign Esophageal Disease Source Type: research
Single ‐center prospective study of Plummer–Vinson syndrome
Summary
Post‐cricoid web is an uncommon cause for dysphagia and is most frequently reported in middle‐aged women. Triad of web, iron deficiency anemia (IDA), and dysphagia is known as Plummer–Vinson syndrome (PVS). Literature on PVS is very limited. Here we report the first prospective study of PVS with predefined diagnostic criteria and management plan. Adults with dysphagia or those incidentally found to have esophageal web were prospectively enrolled between July 2011 and June 2013. Participants were evaluated with hemogram, barium swallow, and esophagogastroduodenoscopy. PVS was diagnosed if a person had IDA and ...
Source: Diseases of the Esophagus - July 29, 2015 Category: Gastroenterology Authors: A. Goel, C. P. Lakshmi, S. S. Bakshi, N. Soni, S. Koshy Tags: Benign Esophageal Disease Source Type: research
