Management and outcome of esophageal stenting for spontaneous esophageal perforations
In this study, we evaluated the clinical efficacy and the outcome of covered self‐expanding stent (CSES) treatment of SEP. All patients with SEP treated by CSES at our institution between 2005 and 2014 were included in this prospective single‐center study. The data were collected from a prospective database based on clinical, endoscopic and operative reports. Follow‐up data were procured by contacting the patients or their family doctors. The patient data were analyzed concerning course of treatment, leakage sealing rate, complications, and mortality. Patients with iatrogenic or malignant perforations were excluded. ...
Source: Diseases of the Esophagus - September 30, 2016 Category: Gastroenterology Authors: Torben Glatz, Goran Marjanovic, Birte Kulemann, Julian Hipp, Ulrich Theodor Hopt, Andreas Fischer, Hans ‐Jürgen Richter‐Schrag, Jens Hoeppner Tags: Original Article Source Type: research
Modified anastomotic technique for thoracolaparoscopic Ivor Lewis esophagectomy: early outcomes and technical details
Summary
Thoracoscopic intrathoracic esophagogastrostomy is a technically demanding operation; these technical requirements restrict the extensive application of minimally invasive Ivor Lewis esophagectomy. In an attempt to reduce the difficulty of this surgical procedure, we developed a modified anastomotic technique for thoracolaparoscopic Ivor Lewis esophagectomy. During the entirety of this modified approach, neither technically challenging operations such as intrathoracic suturing, or knotting, nor special instruments such as an OrVil system or a reverse‐puncture head are required. Between Octomber 2015 and January 2...
Source: Diseases of the Esophagus - September 30, 2016 Category: Gastroenterology Authors: Hanlu Zhang, Longqi Chen, Yingcai Geng, Yu Zheng, Yun Wang Tags: Original Article Source Type: research
Submucosal tunneling endoscopic resection using methylene ‐blue guidance for cardial subepithelial tumors originating from the muscularis propria layer
Summary
Submucosal tunneling endoscopic resection (STER) of subepithelial tumors (SETs) originating from the muscularis propria (MP) layer in the cardia is rarely performed due to the difficulty of creating a submucosal tunnel for resection. The aim of this study was to evaluate the feasibility of STER using methylene‐blue guidance for SETs originating from the MP layer in the cardia. From January 2012 to December 2014, 56 patients with SETs originating from the MP layer in the cardia were treated with STER using methylene‐blue guidance. The complete resection rate and adverse event rate were the main outcome measureme...
Source: Diseases of the Esophagus - September 25, 2016 Category: Gastroenterology Authors: Xin ‐Li Mao, Li‐Ping Ye, Hai‐Hong Zheng, Xian‐Bin Zhou, Lin‐Hong Zhu, Yu Zhang Tags: Original Article Source Type: research
Nasogastric decompression following esophagectomy: a systematic literature review and meta ‐analysis
Summary
Routine use of nasogastric tubes for gastric decompression has been abolished in nearly all types of gastro‐intestinal surgery after introduction of enhanced recovery after surgery programs. However, in esophagectomy the routine use of nasogastric decompression is still a matter of debate. To determine the effects of routine nasogastric decompression following esophagectomy compared with early or peroperative removal of the nasogastric tube on pulmonary complications, anastomotic leakage, mortality, and postoperative recovery. A systematic literature review and meta‐analysis of studies comparing early or perope...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: Teus J. Weijs, Koshi Kumagai, Gijs H. K. Berkelmans, Grard A. P. Nieuwenhuijzen, Magnus Nilsson, Misha D. P. Luyer Tags: Original Article Source Type: research
Comparison of three ‐dimensional conformal radiation therapy, intensity‐modulated radiation therapy, and volumetric‐modulated arc therapy in the treatment of cervical esophageal carcinoma
Summary
The aim of this study was to evaluate the effectiveness and toxicities of three‐dimensional conformal radiation therapy (3DCRT), intensity‐modulated radiation therapy (IMRT), and volumetric‐modulated arc therapy (VMAT) in patients with cervical esophageal cancer. Specifically, we asked whether technological advances conferred an advantage with respect to the clinical curative effect. Seventy‐eight patients with cervical esophageal cancer treated with definitive radiotherapy with or without concomitant chemotherapy at our institution between 2007 and 2014 were enrolled in the study: 26 received 3DCRT, 30 wer...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: Hao Yang, Cong Feng, Bo ‐Ning Cai, Jun Yang, Hai‐Xia Liu, Lin Ma Tags: Original Article Source Type: research
Systematic review of the use of endo ‐luminal topical negative pressure in oesophageal leaks and perforations
Summary
Topical negative pressure is widely used in the management of superficial wounds. The use of this technology in the management of oesophageal perforations is becoming increasingly common. This systematic review aims to capture available evidence about its use in this setting. Medline and Embase were searched using MeSH terms and free text: esophageal perforation; esophageal injury; vacuum assisted closure; vacuum therapy device; esophagus; wounds penetrating; esophageal perforation; wound healing; negative pressure wound therapy. Searches were carried out between April and November 2015. Case series, cohort trials ...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: N. J. Newton, A. Sharrock, R. Rickard, M. Mughal Tags: Original Article Source Type: research
Promoter DNA methylation of CDO1 gene and its clinical significance in esophageal squamous cell carcinoma
Summary
We have demonstrated that CDO1 methylation is frequently found in various cancers, including esophageal squamous cell carcinoma (ESCC), but its clinical relevance has remained elusive. CDO1 methylation was investigated in 169 ESCC patients who underwent esophagectomy between 1996 and 2007. CDO1 methylation was assessed by Q‐MSP (quantitative methylation specific PCR), and its clinical significance, including its relationship to prognosis, was analyzed. (i) The median TaqMeth value of CDO1 methylation was 9.4, ranging from 0 to 279.5. CDO1 methylation was significantly different between cStage I and cStage II/III ...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: Hideki Ushiku, Keishi Yamashita, Hiroshi Katoh, Akira Ema, Naoko Minatani, Mariko Kikuchi, Ken Kojo, Keigo Yokoi, Toshimichi Tanaka, Nobuyuki Nishizawa, Satoru Ishii, Kei Hosoda, Hiromitsu Moriya, Hiroaki Mieno, Natsuya Katada, Shiro Kikuchi, Masahiko Wat Tags: Original Article Source Type: research
The impact of the speed of food intake on gastroesophageal reflux events in obese female patients
Summary
Obesity increases the risk of gastroesophageal reflux disease (GERD). The majority of the reflux attacks occur postprandially. The influence of the speed of food intake on gastroesophageal reflux events is unclear in obese patients. To determine the influence of the speed of food intake on intraesophageal reflux events in obese patients with and without GERD. A total of 26 obese female patients were recruited. The patients underwent esophageal manometry to evaluate the upper limit of the lower esophageal sphincter and subsequently placement of a Multichannel intraluminal impedance‐pH (MII‐pH) catheter. All pati...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: Serhat Bor, Askin Erdogan, Berna Bayrakci, Esra Yildirim, Rukiye Vardar Tags: Original Article Source Type: research
Use of a positional therapy device significantly improves nocturnal gastroesophageal reflux symptoms
Summary
The aim of this study was to measure the efficacy of a positional therapy device (PTD) at reducing proton pump inhibitor (PPI) refractory nocturnal GERD symptoms. Among patients with GERD, nocturnal symptoms are very common. A recent study demonstrated a decrease in nocturnal acid exposure and reflux episodes in healthy volunteers who slept using a PTD. This is a single‐center prospective trial involving patients on anti‐secretory medications with continued nocturnal heartburn and regurgitation. Patients completed the Nocturnal GERD Symptom Severity and Impact Questionnaire (N‐GSSIQ) and GERD health‐related...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: S. Allampati, R. Lopez, P. N. Thota, M. Ray, S. Birgisson, S. L. Gabbard Tags: Original Article Source Type: research
Distribution patterns of metastases in recurrent laryngeal nerve lymph nodes in patients with squamous cell esophageal cancer
Summary
Esophageal cancers frequently metastasize to recurrent laryngeal nerve lymph nodes (RLNNs). Knowledge of anatomic metastatic RLNN (mRLNN) distributions is needed for lymph node dissection during esophageal cancer surgery. Among 189 patients with esophageal cancer who underwent esophagectomy between 2008 and 2010, 51 (27.0%) had mRLNN. Sixty‐four mRLNNs (right, 31; left, 33) were identified via preoperative computed tomography (CT); more than 2 unilateral metastases and/or nodes with unclear boundaries were excluded. Anatomical characteristics, including vertical distance from the sternal notch level, circumferent...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: Takashi Kanemura, Tomoki Makino, Yasuhiro Miyazaki, Tsuyoshi Takahashi, Yukinori Kurokawa, Makoto Yamasaki, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki Tags: Original Article Source Type: research
Health ‐related quality of life and physiological measurements in achalasia
Summary
The diagnosis of achalasia is generally made based on patient symptoms, the appearance of the esophagus on endoscopy and barium esophagogram, and esophageal manometry. In addition, timed barium esophagography (TBE) can give useful information on the clearance of liquid barium over a 10 minute period and the passage of a barium tablet. What is unclear is how well these physiological measurements of esophageal function correlate with patient‐perceived health‐related quality of life. Our aim was to assess whether objective physiological measurements of high‐resolution manometry (HRM) and TBE will correlate with ...
Source: Diseases of the Esophagus - September 14, 2016 Category: Gastroenterology Authors: Daniel Ross, Joel Richter, Vic Velanovich Tags: Original Article Source Type: research
Author Index
(Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - September 8, 2016 Category: Gastroenterology Tags: Abstracts from the 2016 ISDE World Congress Source Type: research
Abstract
(Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - September 8, 2016 Category: Gastroenterology Tags: Abstracts from the 2016 ISDE World Congress Source Type: research
Issue Information
(Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - September 8, 2016 Category: Gastroenterology Tags: Issue Information Source Type: research
Isolated local recurrence or solitary solid organ metastasis after esophagectomy for cancer is not the end of the road
Summary
Recurrent disease after esophagectomy bears an infaust prognosis, especially when multiple recurrences are present. But little is known about survival in patients with limited recurrence (solitary locoregional recurrence or solid organ metastasis). Herein, we report our experience with these subgroups. We analyzed 1754 consecutive patients surgically treated with curative resection for esophageal cancer and cancer of the gastroesophageal junction between 1990 and 2012. Seven subgroups were defined according to the recurrence type (locoregional vs. organ metastasis), the site of recurrence (abdominal, thoracic, cerv...
Source: Diseases of the Esophagus - August 31, 2016 Category: Gastroenterology Authors: L. Depypere, T. Lerut, J. Moons, W. Coosemans, G. Decker, H. Van Veer, P. De Leyn, P. Nafteux Tags: Original Article Source Type: research
