Cytotoxic Activities of Eosinophil Cationic Protein and Eosinophil-derived Neurotoxin: In Silico Analysis
Conclusion: The greater cationicity of ECP may be related to its higher cytotoxicity and to the fact that the varying post-translational modification profiles can generate functional differences from structural alteration. In vivo and in vitro studies need to be performed in order to confirm these predictions. (Source: Cancer Genomics and Proteomics)
Source: Cancer Genomics and Proteomics - November 5, 2015 Category: Cancer & Oncology Authors: DE OLIVEIRA, P. C. R., DE OLIVEIRA LOPES, D., DO VALE COELHO, I. E., PEREIRA, M. C. Tags: Article Source Type: research
Significant Association of Caveolin-1 and Caveolin-2 with Prostate Cancer Progression
Conclusion: There was a significant correlation between plasma CAV-1 and -2 levels and progression of PC. CAV1 and -2 were highly expressed in the PC3 compared to the LNCaP cell line. Our findings support the potential of these molecules as therapeutic targets for CRPC. (Source: Cancer Genomics and Proteomics)
Source: Cancer Genomics and Proteomics - November 5, 2015 Category: Cancer & Oncology Authors: SUGIE, S., MUKAI, S., YAMASAKI, K., KAMIBEPPU, T., TSUKINO, H., KAMOTO, T. Tags: Article Source Type: research
