Endoscopic management of upper tract urothelial cancer: Improved prediction of invasive cancer using a ureteroscopic scoring model
The aim of this study was to investigate clinical and ureteroscopic factors considered as important for the prediction of invasive upper tract urothelial cancer (UTUC) and establish a model using a new ureteroscopic scoring. (Source: Surgical Oncology)
Source: Surgical Oncology - April 17, 2017 Category: Surgery Authors: Seong Soo Jeon, Hyun Hwan Sung, Hwang Gyun Jeon, Deok Hyun Han, Byong Chang Jeong, Seong Il Seo, Hyun Moo Lee, Han-Yong Choi Source Type: research
Spleen-preserving lymphadenectomy versus splenectomy in laparoscopic total gastrectomy for advanced gastric cancer
To investigate the optimal approach for laparoscopic splenic hilum lymph node dissection in proximal advanced gastric cancer, we compared the operative outcomes between laparoscopic spleen-preserving total gastrectomy (sp-LTG) and laparoscopic total gastrectomy with splenectomy (sr-LTG). (Source: Surgical Oncology)
Source: Surgical Oncology - April 15, 2017 Category: Surgery Authors: Sang-Yong Son, Dong Joon Shin, Young Suk Park, Aung Myint Oo, Do-Hyun Jung, Chang Min Lee, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim Source Type: research
Is hyperthermic intraperitoneal chemotherapy (HIPEC) safe for healthcare workers?
During hyperthermic intraperitoneal chemotherapy (HIPEC), caregivers are exposed by different routes to cytotoxic drugs. This review proposes an overview of the safety of HIPEC by assessing existing data on protection procedures, biological and non-biological samples. Based on these data, relevant good practices, eventual irrelevant overprotection procedures and missing data to implement adapted protections are highlighted. (Source: Surgical Oncology)
Source: Surgical Oncology - April 14, 2017 Category: Surgery Authors: Simon Rodier, Guillaume Saint-Lorant, Jean-Marc Guilloit, Agn ès Palix, Fabienne Divanon, François Sichel, Raphaël Delépée Source Type: research
Socioeconomic and gender disparities in anal cancer diagnosis and treatment
We investigated whether receipt of radiation in patients with anal carcinoma is related to income level and other demographic factors. (Source: Surgical Oncology)
Source: Surgical Oncology - April 6, 2017 Category: Surgery Authors: Karel-Bart Celie, Christopher Jackson, Surbhi Agrawal, Chetan Dodhia, Carlos Guzman, Theodor Kaufman, Nicholas Hellenthal, Daphne Monie, Jose Monzon, Luis Oceguera Source Type: research
Title: Socioeconomic and gender disparities in anal cancer diagnosis and treatment
We investigated whether receipt of radiation in patients with anal carcinoma is related to income level and other demographic factors. (Source: Surgical Oncology)
Source: Surgical Oncology - April 6, 2017 Category: Surgery Authors: Karel-Bart Celie, Christopher Jackson, Surbhi Agrawal, Chetan Dodhia, Carlos Guzman, Theodor Kaufman, Nicholas Hellenthal, Daphne Monie, Jose Monzon, Luis Oceguera Source Type: research
Updates in hepatic oncology imaging
The utilization of advanced imaging modalities play an important role in the detection and differentiation of benign and malignant hepatic lesions. Imaging characteristics of hepatic tumors can sometimes be atypical, often leading to diagnostic challenges. Recent technical improvements in contrast enhanced ultrasound (CEUS), computed tomography (CT), and magnetic resonance imaging (MRI) have helped to better characterize hepatic lesions. For example, contrast agents used in US can now better delineate liver lesions, while the ability to reliably produce multiplanar and 3-D reconstructions through the use of MDCT provides a...
Source: Surgical Oncology - April 6, 2017 Category: Surgery Authors: Pallavi Pandey, Heather Lewis, Ankur Pandey, Carl Schmidt, Mary Dillhoff, Ihab R. Kamel, Timothy M. Pawlik Source Type: research
Postoperative liver volume was accurately predicted by a medical image three dimensional visualization system in hepatectomy for liver cancer
Liver cancer is the second most common cause of cancer death worldwide. The hepatectomy is the most effective and the only potentially curative treatment for patients with resectable neoplasm. Precisely preoperative assessment of remnant liver volume is essential in preventing postoperative liver failure. The aim of our study is to report our experience of using a medical image three dimensional (3D) visualization system (MI-3DVS), which was developed by our team, in assisting hepatectomy for patients with liver cancer. (Source: Surgical Oncology)
Source: Surgical Oncology - March 17, 2017 Category: Surgery Authors: Wei Cai, Yingfang Fan, Haoyu Hu, Nan Xiang, Chihua Fang, Fucang Jia Source Type: research
Postoperative infections after limb-sparing surgery for primary bone tumors of the pelvis: Incidence, characterization and functional impact
Surgical site infections (SSI) represent the most common postoperative complication after limb sparing surgery for primary malignant bone tumors, with incidence ranging from 10 to 47%. There is no consensus concerning about the optimal surgical strategy, or the adequate antibiotic prophylaxis in pelvic resections. A greater knowledge of these infections and their surgical trajectories seem essential to obtain. (Source: Surgical Oncology)
Source: Surgical Oncology - March 15, 2017 Category: Surgery Authors: M. Severyns, S. Briand, D. Waast, S. Touchais, A. Hamel, F. Gouin Source Type: research
Identification of the resection severity index as a significant independent prognostic factor for early mortality and observed survival < 5 and < 10 years after liver resection for hepatocellular carcinoma
This study evaluates predictive factors for observed long-term survival of more than 5 and 10 years for patients after liver resection for hepatocellular carcinoma and compares their life expectancy to the normal national population matched for sex, year of birth and age at resection. (Source: Surgical Oncology)
Source: Surgical Oncology - March 15, 2017 Category: Surgery Authors: Jill Gwiasda, Aron Schulte, Alexander Kaltenborn, Wolf Ramackers, Moritz Kleine, Oliver Beetz, J ürgen Klempnauer, Nikos Emmanouilidis, Harald Schrem Source Type: research
Minimal impact of postmastectomy radiation therapy on locoregional recurrence for breast cancer patients with 1 to 3 positive lymph nodes in the modern treatment era
Given modern treatment strategies, controversy remains regarding whether postmastectomy radiation therapy (PMRT) is necessary for breast cancer patients with 1 –3 positive axillary lymph nodes (ALN). Our aim was to assess the significance of PMRT in the modern treatment era for these patients. (Source: Surgical Oncology)
Source: Surgical Oncology - March 14, 2017 Category: Surgery Authors: Minoru Miyashita, Hiroshi Tada, Akihiko Suzuki, Gou Watanabe, Hisashi Hirakawa, Masakazu Amari, Yoichiro Kakugawa, Masaaki Kawai, Akihiko Furuta, Kaoru Sato, Ryuichi Yoshida, Akiko Ebata, Hironobu Sasano, Keiichi Jingu, Noriaki Ohuchi, Takanori Ishida Source Type: research
SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery
Fluorescence-guided surgery (FGS) provides surgeons with new opportunities to improve real-time cancer nodule detection and tumor margin visualization. Currently, the most important challenge in this field is the development of fluorescent dyes that specifically target tumors. We developed, characterized and evaluated SGM-101, an innovative antibody-dye conjugate in which the fluorochrome BM104, which has an absorbance band centered at 700 nm, is coupled to a chimeric monoclonal antibody (mAb) against carcinoembryonic antigen (CEA). (Source: Surgical Oncology)
Source: Surgical Oncology - March 8, 2017 Category: Surgery Authors: Marian Gutowski, B érénice Framery, Martin C. Boonstra, Véronique Garambois, François Quenet, Karen Dumas, François Scherninski, Françoise Cailler, Alexander L. Vahrmeijer, André Pèlegrin Source Type: research
Multidisciplinary management of intrahepatic cholangiocarcinoma: Current approaches
Intrahepatic cholangiocarcinoma (ICC) is a common primary hepatic tumor. However, its outcomes are usually worse than those of hepatocellular carcinoma owing to its non-specific presentation and detection at an advanced stage. The most widely used serum marker, carbohydrate antigen 19-9, is non-specific. Furthermore, imaging studies rarely identify any pathognomonic features. Surgery is the only treatment option that offers a chance of long-term survival. However, the resectability rate is low owing to the high frequencies of intrahepatic metastases, peritoneal carcinomatosis, or extrahepatic metastases. (Source: Surgical Oncology)
Source: Surgical Oncology - March 6, 2017 Category: Surgery Authors: Hanisah Guro, Jin Won Kim, YoungRok Choi, Jai Young Cho, Yoo-Seok Yoon, Ho-Seong Han Source Type: research
Editorial Board/Aims and Scope
(Source: Surgical Oncology)
Source: Surgical Oncology - March 1, 2017 Category: Surgery Source Type: research
Personalized therapy in hepatocellular carcinoma: Molecular markers of prognosis and therapeutic response
Hepatocellular carcinoma (HCC) represents a growing worldwide health crisis with rising incidence, limited effective therapies and persistently poor prognosis. Five-year survival remains less than 20% despite decades of research. One byproduct of research efforts is the identification of numerous biomarkers of disease. From prognosis to therapeutic response, biomarker identification parallels a deeper molecular understanding of the disease that to date has generated limited gain in clinical outcomes. (Source: Surgical Oncology)
Source: Surgical Oncology - February 19, 2017 Category: Surgery Authors: Richard A. Burkhart, Sean M. Ronnekleiv-Kelly, Timothy M. Pawlik Source Type: research
Intrahepatic cholangiocarcinoma: Molecular markers for diagnosis and prognosis
Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver tumor with increasing incidence worldwide. The outcome of patients with iCCA is dismal owing to tumor's aggressiveness, late diagnosis and lack of effective treatment options. Detection of the tumor at early stages may make surgical resection, as only potential curative treatment, more feasible. Unfortunately, despite recent developments in imaging modalities and laboratory tests, the diagnosis of iCCA remains challenging and patients often present in advanced stages when surgery cannot be offered. (Source: Surgical Oncology)
Source: Surgical Oncology - February 18, 2017 Category: Surgery Authors: Amir A. Rahnemai-Azar, Allison Weisbrod, Mary Dillhoff, Carl Schmidt, Timothy M. Pawlik Tags: Review Source Type: research
