Systematic review of the surgical strategies of Adenocarcinomas of the gastroesophageal junction
The optimal surgical treatment of patients with adenocarcinoma of the gastroesophageal junction has not been established yet. (Source: Surgical Oncology)
Source: Surgical Oncology - October 28, 2014 Category: Surgery Authors: L. Haverkamp, J.P. Ruurda, M.S. Van Leeuwen, P.D. Siersema, R. van Hillegersberg Tags: Review Source Type: research

Quality Of Life After Cytoreductive Surgery And Hyperthermic Intra-Peritoneal Chemotherapy For Peritoneal Carcinomatosis: A Systematic Review And Meta-Analysis
To review the effect of cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy (HIPEC) on health-related quality of life (HRQOL) in patients with peritoneal carcinomatosis. (Source: Surgical Oncology)
Source: Surgical Oncology - October 27, 2014 Category: Surgery Authors: Leonard L. Shan, Akshat Saxena, Bernard L. Shan, David L. Morris Tags: Review Source Type: research

Palliative percutaneous stabilization of lower extremity for bone metastasis using flexible nails and bone cement
Percutaneous stabilization (PS; percutaneous flexible nailing and intramedullary bone cement injection) was performed at lower extremity long bones in patients with multiple bone metastases with short life expectancy to get mechanical stability and local tumor control. We evaluated the usefulness of PS by clinical status, F-18-FDG PET-CT and bone scintigraphy (BS). (Source: Surgical Oncology)
Source: Surgical Oncology - September 30, 2014 Category: Surgery Authors: Yong-il Kim, Hyun Guy Kang, Tae Sung Kim, Seok-ki Kim, June Hyuk Kim, Han Soo Kim Tags: Review Source Type: research

Factors which affect use of breast conservation and mastectomy in an underinsured Hispanic population
Despite no difference in overall survival between breast conservation and mastectomy, significant variation exists between institutions and within populations. Less data exists about racial and ethnic minority populations. The current study was performed to evaluate variables that affect use of breast conservation and mastectomy in an underinsured Hispanic population. (Source: Surgical Oncology)
Source: Surgical Oncology - September 20, 2014 Category: Surgery Authors: Lyndsay Olsen-Deeter, Chiu-Hsieh Hsu, Jesse N. Nodora, Marcia E. Bouton, Justin Nalagan, Maria Elena Martinez, Ian K. Komenaka Tags: Review Source Type: research

Editorial Board/Aims and Scope
(Source: Surgical Oncology)
Source: Surgical Oncology - September 1, 2014 Category: Surgery Source Type: research

The role of hepatectomy in the management of metastatic gastric adenocarcinoma: A systematic review
Gastric cancer has a high mortality, with many patients presenting with advanced disease. Many patients who undergo curative gastrectomy will subsequently develop metastatic disease. Hepatectomy has an established place in treating metastases from a variety of cancers but its role in gastric cancer is not clear. This review sought to systematically appraise the literature to establish the role of hepatectomy in treating gastric cancer metastases. (Source: Surgical Oncology)
Source: Surgical Oncology - August 11, 2014 Category: Surgery Authors: Nathan Grimes, Joanne Devlin, Declan FJ. Dunne, Graeme Poston, Stephen Fenwick, Hassan Malik Tags: Review Source Type: research

The effect of neoadjuvant radiation therapy on perioperative outcomes among patients undergoing resection of retroperitoneal sarcomas
Neoadjuvant radiation therapy (RT) has several theoretical benefits in the treatment of retroperitoneal sarcoma (RPS), but concerns remain about treatment toxicity and perioperative morbidity. There are limited data regarding its effect on perioperative outcomes, most of which come from small, single-institution series. The purpose of this study was to evaluate the short-term (30-day) postoperative morbidity and mortality associated with neoadjuvant RT following resection of RPS. (Source: Surgical Oncology)
Source: Surgical Oncology - July 23, 2014 Category: Surgery Authors: Daniel P. Nussbaum, Paul J. Speicher, Brian C. Gulack, Asvin M. Ganapathi, Jeffrey E. Keenan, Sandra S. Stinnett, David G. Kirsch, Douglas S. Tyler, Dan G. Blazer Tags: Review Source Type: research

The clinical perspectives of CDX2 expression in colorectal cancer: A qualitative systematic review
Homeobox genes are often deregulated in cancer. They can have both oncogenic and tumor-suppressing potential. The Caudal-related homeobox transcription factor 2 (CDX2) is an intestine-specific transcription factor. It is implicated in differentiation, proliferation, cell-adhesion, and migration. CDX2 has been proposed as a tumor suppressor in colorectal cancer but its role is still controversial. This systematic review were undertaken in order to clarify CDX2s role in colorectal cancer. (Source: Surgical Oncology)
Source: Surgical Oncology - July 16, 2014 Category: Surgery Authors: J. Olsen, M.L.M. Espersen, P. Jess, L.T. Kirkeby, J.T. Troelsen Tags: Review Source Type: research

Thyroglossal duct remnant carcinoma: Beyond the Sistrunk procedure
Thyroglossal duct remnants (TGDRs) account for more than 70% of anterior neck masses in children and 7% in adults; however, cancer is identified in only 1–2% of the cases. The diagnosis of a TGDR is based on clinical manifestation of a painless, anterior neck swelling, which elevates with swallowing. Cytological evaluation with fine needle aspiration and biopsy (FNAB) may facilitate the pre-operative diagnosis of malignancy, as the majority of TGDR cancers are of papillary histotype. The recommended treatment for symptomatic TGDR without evidence of malignancy is a Sistrunk procedure, which entails en bloc resection of t...
Source: Surgical Oncology - July 10, 2014 Category: Surgery Authors: Yvette Carter, Nicholas Yeutter, Haggi Mazeh Tags: Review Source Type: research

Simultaneous versus staged hepatic resection for colorectal metastases with an intact primary cancer
Currently, there are approximately 103,170 new cases of colon cancer and 40,290 new cases of rectal cancer diagnosed yearly. Approximately 51,690 deaths occur from colorectal cancers annually. Colon and rectal cancer combined are the fourth most common cancer diagnosis and second most common cause of cancer mortality. While the incidence and mortality are decreasing, about half of all patients will develop metastatic disease. Of these patients, 80–90% develops unresectable liver metastases, which include 20–34% who have synchronous hepatic metastases. (Source: Surgical Oncology)
Source: Surgical Oncology - June 27, 2014 Category: Surgery Authors: Joseph Bennett, Brian Frank, Peter Santoro Tags: Commentary Source Type: research

A microRNA gene signature for identification of lung cancer
Lung cancer is the leading cause of cancer deaths worldwide, compounded by late diagnosis. MicroRNAs (miRNA) are recently discovered short, noncoding genes that play essential roles in tissue differentiation during normal development and tumorigenesis. miRNA profiles across all histologic grades can provide a reliable and standardized method for the identification of lung cancer. (Source: Surgical Oncology)
Source: Surgical Oncology - June 26, 2014 Category: Surgery Authors: Zhiqiang Xue, Jiaxin Wen, Xiangyang Chu, Xinying Xue Tags: Review Source Type: research