Decreased physical activity in adults with bronchial asthma
Contradictory findings have been reported in the literature on the impact that bronchial asthma may have on habitual physical activity. The present study was designed to compare physical activity, objectively measured with an activity monitor, between adults with bronchial asthma and apparently healthy controls.Valid registrations of physical activity were obtained in 226 patients with asthma and 201 healthy controls. A multiple general linear model was used to test between group differences and to correct for confounding of the results due to between group differences in BMI and employment status. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 21, 2016 Category: Respiratory Medicine Authors: Alex J. van 't Hul, Siete Frouws, Edmee van den Akker, Rob van Lummel, Anja Starrenburg-Razenberg, Alie van Bruggen, Gert-Jan Braunstahl, Johannes C.C.M. in 't Veen Source Type: research

Assessment of Sleep Quality Post-Hospital Discharge in Survivors of Critical Illness
Sleep quality is impaired during critical illness and may remain abnormal after discharge from hospital. Sleep dysfunction in patients after critical illness may impair recovery and health related quality of life. The purpose of this study was to use objective and subjective measures to evaluate sleep quality in critical illness survivors 3 months after hospital discharge. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 20, 2016 Category: Respiratory Medicine Authors: Kevin J. Solverson, Paul A. Easton, Christopher J. Doig Source Type: research

Predictors of survival in coexistent hypersensitivity pneumonitis with autoimmune features
In this study, we examined an HP cohort to identify those with HP and autoimmune features (HPAF), and determine its prevalence and outcomes. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 20, 2016 Category: Respiratory Medicine Authors: Ayodeji Adegunsoye, Justin M. Oldham, Carley Demchuk, Steven Montner, Rekha Vij, Mary E. Strek Source Type: research

Decreased prevalence of moderate to severe COPD over 15 years in northern Sweden
The burden of COPD in terms of mortality, morbidity, costs and prevalence has increased worldwide. Recent results on prevalence in Western Europe are conflicting. In Sweden smoking prevalence has steadily decreased over the past 30 years. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 20, 2016 Category: Respiratory Medicine Authors: Helena Backman, Berne Eriksson, Eva Rönmark, Linnea Hedman, Caroline Stridsman, Sven-Arne Jansson, Anne Lindberg, Bo Lundbäck Source Type: research

Chronic obstructive pulmonary disease in Denmark: Age-period-cohort analysis of first-time hospitalisations and deaths 1994-2012
During the 80s and 90s the mortality and number of hospitalisations due to chronic obstructive pulmonary disease (COPD) in the country of Denmark almost doubled. Since then there has been a plateau.Objective: to analyse age, period, and cohort effects on rates of deaths and first-time hospitalisations with COPD in Denmark during the period from 1994 to 2012 and to make a forecast of these parameters. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 20, 2016 Category: Respiratory Medicine Authors: Jesper Lykkegaard, Gustav N. Kristensen Source Type: research

Clinical improvement by Tiotropium plus olodaterol
In this study, patients were allowed to continue their inhaled corticosteroid (ICS) therapy, and 34.8 to 41.9% of patients had ICS in each group of the patients. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 19, 2016 Category: Respiratory Medicine Authors: Tomohiro Tamura, Katsunori Kagohashi, Hiroaki Satoh Tags: Correspondence Source Type: research

Increased serum VDBP as a risk predictor for steroid resistance in asthma patients
Asthmatic symptoms usually can be controlled with corticosteroids, but partly asthmatic patients do not respond to corticosteroids, steroid resistance (SR) play a significant role in the poorly responding. However, no approach can accurately predict steroid responsiveness in asthma patients, so prediction of SR with noninvasive means has become a critical issue. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 19, 2016 Category: Respiratory Medicine Authors: Hongjuan Jiang, Xiangyu Chi, Xuan Zhang, Jing Wang Source Type: research

Clinical improvement by tiotropium plus olodaterol
In this study, patients were allowed to continue their inhaled corticosteroid (ICS) therapy, and 34.8–41.9% of patients had ICS in each group of the patients. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 18, 2016 Category: Respiratory Medicine Authors: Tomohiro Tamura, Katsunori Kagohashi, Hiroaki Satoh Tags: Correspondence Source Type: research

Lung cancer diagnosed following an emergency admission: mixed methods study of the management, outcomes and needs and experiences of patients and carers
In the UK, although 40% of patients with lung cancer are diagnosed following an emergency admission (EA), data is limited on their needs and experiences as they progress through diagnostic and treatment pathways. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 14, 2016 Category: Respiratory Medicine Authors: Andrew Wilcock, Vincent Crosby, Asmah Hussain, Tricia M. McKeever, Cathann Manderson, Sarah Farnan, Sarah Freer, Alison Freemantle, Fran Littlewood, Glenys Caswell, Jane Seymour Source Type: research

Effects of individual and neighborhood socioeconomic status on the risk of all-cause mortality in chronic obstructive pulmonary disease: A nationwide population-based cohort study, 2002–2013
Numerous previous studies have shown that individual socioeconomic status (SES) is associated with mortality in patients with chronic obstructive pulmonary disease (COPD), but few empirical studies have evaluated the effects of individual SES and neighborhood deprivation on mortality in COPD patients. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 11, 2016 Category: Respiratory Medicine Authors: Kyoung Hee Cho, Chung Mo Nam, Eun Jung Lee, Young Choi, Ki-Bong Yoo, Seon-Heui Lee, Eun-Cheol Park Source Type: research

Endotoxin Exposure, Serum Vitamin D, Asthma and Wheeze Outcomes
Endotoxin has been shown to induce neutrophilic asthma and wheeze after binding toll-like receptor 4 to produce pro-inflammatory cytokines. Animal models have demonstrated that vitamin D might inhibit lipopolysaccharide-induced cytokines. However, whether endotoxin exposure and serum vitamin D deficiency interact to affect asthma and wheeze in humans has never been investigated in an epidemiological study. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 11, 2016 Category: Respiratory Medicine Authors: Angelico Mendy, Richard D. Cohn, Peter S. Thorne Source Type: research

Post-tuberculous lung function impairment in a tuberculosis reference clinic in Cameroon
This study aimed to determine the prevalence of lung function impairment in patients treated for pTB and investigate its associated factors. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 11, 2016 Category: Respiratory Medicine Authors: Bertrand Hugo Mbatchou Ngahane, Junior Nouyeb, Malea Nganda Motto, Mapoure Njankouo Yacouba, Adeline Wandji, Mireille Endalle, Emmanuel Afane Ze Source Type: research

The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline
The German COPD cohort study COSYCONET (“COPD and SYstemic consequences-COmorbidities NETwork”) investigates the interaction of lung disease, comorbidities and systemic inflammation. Recruitment took place from 2010-2013 in 31 study centers. In addition to the baseline visit, follow-up visits are scheduled at 6, 18, 36 and 54 months after baseline. The study also comprises a biobank, image bank, and includes health economic data. Here we describe the study design of COSYCONET and present baseline data of our COPD cohort. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 11, 2016 Category: Respiratory Medicine Authors: A. Karch, C. Vogelmeier, T. Welte, R. Bals, H.U. Kauczor, J. Biederer, J. Heinrich, H. Schulz, S. Gläser, R. Holle, H. Watz, S. Korn, N. Adaskina, F. Biertz, C. Vogel, J. Vestbo, E.F.M. Wouters, K.F. Rabe, S. Söhler, A. Koch, R.A. Jörres, the COSYCONET Source Type: research

Associations of cognition with physical functioning and health-related quality of life among COPD patients
Neurocognitive impairment has been described in COPD patients, but little is known about its relationship with physical functioning and health-related quality of life (HRQL) in this chronically ill patient group. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 10, 2016 Category: Respiratory Medicine Authors: Mark B. Schure, Soo Borson, Huong Q. Nguyen, Emily H. Trittschuh, Stephen M. Thielke, Kenneth C. Pike, Sandra G. Adams, Vincent S. Fan Source Type: research

Capnometry in children with bronchiolitis: a pathophysiological point of view
Bronchiolitis is the most common lower respiratory tract infection among infants and young children.1 (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 7, 2016 Category: Respiratory Medicine Authors: Colombo Jacopo, Alfio Bronco, Valeria Lippolis, Ezio Bonanomi Tags: Correspondence Source Type: research