Clinical characteristics of patients with hemodialysis-associated pneumonia compared to patients with non-hemodialysis community-onset pneumonia
This study aimed to evaluate the clinical and microbiological characteristics of HDAP patients compared to community-acquired pneumonia (CAP) or other HCAP except HDAP (O-HCAP). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 24, 2015 Category: Respiratory Medicine Authors: Jong Hoo Lee, Jae Chol Moon Source Type: research
Treatment patterns in COPD patients newly diagnosed in primary care. A population-based study
Treatment for COPD is tailored based on clinical characteristics and severity. However, prescription patterns in COPD patients newly diagnosed in primary care may differ from guideline recommendations. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 23, 2015 Category: Respiratory Medicine Authors: Miriam Barrecheguren, Mónica Monteagudo, Jaume Ferrer, Eulalia Borrell, Carl Llor, Cristina Esquinas, Marc Miravitlles Source Type: research
The use of mechanical ventilation in patients with idiopathic pulmonary fibrosis in the United States: a nationwide retrospective cohort analysis
To investigate the mortality of patients with Idiopathic Pulmonary Fibrosis (IPF) who undergo mechanical ventilation (MV) and non-invasive mechanical ventilation (NIMV) in the United States. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 21, 2015 Category: Respiratory Medicine Authors: Barret Rush, Katie Wiskar, Landon Berger, Donald Griesdale Source Type: research
Aberrant small airways function relates to asthma severity in young children
Frequency dependence of resistance (R5-20) assessed by impulse oscillometry (IOS) is suggested to be a measure of small airways. Small airways involvement during induced bronchoconstriction has been shown to reflect severity of asthma in adults. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 19, 2015 Category: Respiratory Medicine Authors: Satu Kalliola, L. Pekka Malmberg, Anna S. Pelkonen, Mika J. Mäkelä Source Type: research
Systemic inflammation and lung function: A longitudinal analysis
Systemic inflammation is associated with impaired lung function in healthy adults as well as in patients with lung disease. The mechanism for this association is unknown and it is unclear if systemic inflammation leads to impaired lung function or if poor lung function leads to inflammation. We explored the temporal associations between blood C-reactive protein (CRP), fibrinogen, and white blood cells, and lung function in young adults. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 19, 2015 Category: Respiratory Medicine Authors: Robert J. Hancox, Andrew R. Gray, Malcolm R. Sears, Richie Poulton Source Type: research
Increased asthma and adipose tissue inflammatory gene expression with obesity and Inuit migration to a western country
An overlap between obesity and asthma exists, and inflammatory cells in adipose tissue could drive the development of asthma. Comparison of adipose tissue gene expression among Inuit living in Greenland to those in Denmark provides an opportunity to assess how changes in adipose tissue inflammation can be modified by migration and diet. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 18, 2015 Category: Respiratory Medicine Authors: Vibeke Backer, Katherine J. Baines, Heather Powell, Celeste Porsbjerg, Peter G. Gibson Source Type: research
The diagnosis of COPD in primary care; gender differences and the role of spirometry
Females with exacerbations of Chronic Obstructive Pulmonary Disease now account for one half of all hospital admissions for that condition and rates have been increasing over the last few decades. Differences in presentations of disease between genders have been shown in several conditions and this study explores whether there are inter gender biases in probable diagnoses in those suspected to have COPD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 18, 2015 Category: Respiratory Medicine Authors: N.J. Roberts, I.S. Patel, M.R. Partridge Source Type: research
Comparison of latent tuberculosis infection rate between contacts with active tuberculosis and non-contacts
Latent tuberculosis infection (LTBI) rate is usually high in contacts with infectious TB patients. In TB-prevalent country, however, background LTBI rate is already high in general population. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 13, 2015 Category: Respiratory Medicine Authors: Jung-Wan Yoo, Kyung-Wook Jo, Gu Young Park, Tae Sun Shim Source Type: research
Direct and indirect costs of COPD and its comorbidities: results from the German COSYCONET study
This study investigates COPD excess healthcare utilization, work absenteeism, and resulting costs within the German COPD cohort COSYCONET. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 9, 2015 Category: Respiratory Medicine Authors: Wacker ME, Jörres RA, Schulz H, Heinrich J, Karrasch S, Karch A, Koch A, Peters A, Leidl R, Vogelmeier C, Holle R Source Type: research
Community acquired pneumonia in asthma: not a threatening combination
Our prospective data collection described a population of consecutive CAP patients from two Spanish hospitals and analysed the severity and outcomes of CAP in a population also affected by asthma in order to evaluate the need for a specific management and/or treatment in these patients. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 8, 2015 Category: Respiratory Medicine Authors: Eva Polverino, Silvia Terraneo, Antoni Torres Source Type: research
Response to Letter to the Editor: Improvements in lung function with umeclidinium/vilanterol versus fluticasone propionate/salmeterol in patients with moderate-to-severe COPD and infrequent exacerbations
On behalf of my co-authors, I would like to thank Dr Banerji and Dr Patalano for their interest in our recently published article demonstrating the benefits of once-daily umeclidinium/vilanterol 62.5/25 mcg (UMEC/VI) versus twice-daily fluticasone propionate/salmeterol 250/50 mcg (FP/SAL) in patients with moderate-to-severe COPD. Dr Banerji and Dr Patalano quite rightly highlight the similarities of our findings and those of the ILLUMINATE and LANTERN studies [1,2], which further support the benefits of combined long-acting muscarinic antagonist (LAMA)/long-acting β2-agonist (LABA) treatments in COPD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - November 27, 2015 Category: Respiratory Medicine Authors: James F. Donohue Source Type: research
Improvements in lung function with umeclidinium/vilanterol versus fluticasone propionate/salmeterol in patients with moderate-to-severe COPD and infrequent exacerbations
On behalf of my co-authors, I would like to thank Dr Banerji and Dr Patalano for their interest in our recently published article demonstrating the benefits of once-daily umeclidinium/vilanterol 62.5/25 mcg (UMEC/VI) versus twice-daily fluticasone propionate/salmeterol 250/50 mcg (FP/SAL) in patients with moderate-to-severe COPD. Dr Banerji and Dr Patalano quite rightly highlight the similarities of our findings and those of the ILLUMINATE and LANTERN studies [1, 2], which further support the benefits of combined long-acting muscarinic antagonist (LAMA)/long-acting β2-agonist (LABA) treatments in COPD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - November 27, 2015 Category: Respiratory Medicine Authors: James F. Donohue Source Type: research
Severity of Community acquired pneumonia in asthma patients. How and what are linked?
We have read with great interest the study by Terraneo et al.[1] on the little explored subject of community-acquired pneumonia (CAP) in asthmatic patients. Although this is described as a prospective study, interventions and evaluations done to the patients differ. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - November 27, 2015 Category: Respiratory Medicine Authors: Emre Erbabacan, Guniz M. Koksal, Antonio M. Esquinas Source Type: research
Gender differences in patients starting long-term home mechanical ventilation due to obesity hypoventilation syndrome
Obesity hypoventilation syndrome (OHS) is often diagnosed late. The aim of this study was to analyse gender differences at initiation of long-term mechanical ventilation (LTMV) in patients with (OHS), to analyse gender differences in treatment effect and to study how the prescription of LTMV due to OHS has changed over time. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - November 26, 2015 Category: Respiratory Medicine Authors: Andreas Palm, Bengt Midgren, Christer Janson, Eva Lindberg Source Type: research
Investigating the association between medication adherence and health-related quality of life in COPD: methodological challenges when using a proxy measure of adherence
The association between non-adherence to medication and health-related quality-of-life (HRQoL) in Chronic Obstructive Pulmonary Disease (COPD) remains poorly understood. Different ways to deal with methodological challenges to estimate this association have probably contributed to conflicting results. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - November 23, 2015 Category: Respiratory Medicine Authors: Melinde R.S. Boland, Job F.M. van Boven, Annemarije L. Kruis, Niels H. Chavannes, Thys van der Molen, Lucas M.A. Goossens, Maureen P.M.H. Rutten-van Mölken Source Type: research
