Organizing pneumonia/non-specific interstitial pneumonia overlap is associated with unfavorable lung disease progression
Overlapping forms of interstitial pneumonia have been recognized, but are likely underappreciated, and their clinical, radiologic, and histologic characteristics are not well-defined. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 30, 2015 Category: Respiratory Medicine Authors: Nevins W. Todd, Ellen T. Marciniak, Ashutosh Sachdeva, Seth J. Kligerman, Jeffrey R. Galvin, Irina G. Luzina, Sergei P. Atamas, Allen P. Burke Source Type: research
Organizing Pneumonia/Non-specific Interstitial Pneumonia Overlap is associated with Unfavorable Lung Disease Progression
Overlapping forms of interstitial pneumonia have been recognized, but are likely underappreciated, and their clinical, radiologic, and histologic characteristics are not well-defined. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 30, 2015 Category: Respiratory Medicine Authors: Nevins W. Todd, Ellen T. Marciniak, Ashutosh Sachdeva, Seth J. Kligerman, Jeffrey R. Galvin, Irina G. Luzina, Sergei P. Atamas, Allen P. Burke Source Type: research
Corrigendum to “Efficacy and safety of umeclidinium added to fluticasone furoate/vilanterol in chronic obstructive pulmonary disease: Results of two randomized studies” [Respir. Med. 109 (2015) 1155–1163]
The authors regret that in the Abbreviations the following term, ‘long-acting muscarinic agonist’, should appear as ‘long-acting muscarinic antagonist’. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 29, 2015 Category: Respiratory Medicine Authors: Thomas M. Siler, Edward Kerwin, Ana R. Sousa, Alison Donald, Rehan Ali, Alison Church Tags: Corrigendum Source Type: research
New developments in inhaler devices within pharmaceutical companies: A systematic review of the impact on clinical outcomes and patient preferences
Pharmaceutical companies offer an increasing number of inhaler devices, whether or not together with new substances, for maintenance treatment of patients with COPD or asthma. However, well-designed studies to support these developments are scarce. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 29, 2015 Category: Respiratory Medicine Authors: Vincent Ninane, Jan Vandevoorde, Didier Cataldo, E. Derom, G. Liistro, Evert Munghen, Rudi Peché, M. Schlesser, G. Verleden, Walter Vincken Source Type: research
Electronic nose analysis of exhaled breath to diagnose ventilator-associated pneumonia
Exhaled breath analysis is an emerging technology in respiratory disease and infection. Electronic nose devices (e-nose) are small and portable with a potential for point of care application. Ventilator-associated pneumonia (VAP) is a common nosocomial infection occurring in the intensive care unit (ICU). The current best diagnostic approach is based on clinical criteria combined with bronchoalveolar lavage (BAL) and subsequent bacterial culture analysis. BAL is invasive, laborious and time consuming. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 28, 2015 Category: Respiratory Medicine Authors: R.M. Schnabel, M.L.L. Boumans, A. Smolinska, E.E. Stobberingh, R. Kaufmann, P.M.H.J. Roekaerts, D.C.J.J. Bergmans Source Type: research
Prevalence and risk factors of COPD among never-smokers in two areas of Sweden – occupational exposure to gas, dust or fumes is an important risk factor
Although active tobacco smoking is the main risk factor for COPD, COPD is not uncommon also among never-smokers. Different study locations along with different spirometric definitions of COPD have historically yielded different prevalence estimates of the disease. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 25, 2015 Category: Respiratory Medicine Authors: Stig Hagstad, Helena Backman, Anders Bjerg, Linda Ekerljung, Xiong Ye, Linnea Hedman, Anne Lindberg, Kjell Torén, Jan Lötvall, Eva Rönmark, Bo Lundbäck Source Type: research
Validation of Human Small Airway Measurements using Endobronchial Optical Coherence Tomography
Small airway remodeling is the cardinal feature underlying chronic airway diseases. There is no modality which identifies small airway pathological changes, which is crucial for early diagnosis, efficacy and prognostic assessment. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 23, 2015 Category: Respiratory Medicine Authors: Yu Chen, Ming Ding, Wei-jie Guan, Wei Wang, Wei-zhan Luo, Chang-hao Zhong, Mei Jiang, Ju-hong Jiang, Ying-ying Gu, Shi-yue Li, Nan-shan Zhong Source Type: research
Persistent airflow obstruction in patients with asthma: Characteristics of a distinct clinical phenotype
In this study we aimed to identify differences in the clinical, functional and inflammatory characteristics between patients with asthma with and without persistent airflow obstruction. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 21, 2015 Category: Respiratory Medicine Authors: Elissavet Konstantellou, Andriana I. Papaioannou, Stelios Loukides, George Patentalakis, Anastasia Papaporfyriou, Georgios Hillas, Spyros Papiris, Nikolaos Koulouris, Petros Bakakos, Konstantinos Kostikas Source Type: research
Combined effects of mild-to-moderate obesity and asthma on physiological and sensory responses to exercise
Despite the close link between asthma and obesity, there are no studies that have evaluated the sensory and physiological responses to exercise in obese asthmatics. We recently demonstrated that normal weight asthmatics with well controlled disease have preserved cardiorespiratory and sensory responses to exercise relative to non-asthmatic controls. However, these similarities may not hold true in patients with combined obesity and asthma. Accordingly, we sought to determine if combined asthma and obesity was associated with deleterious effects on cardiorespiratory fitness, exercise performance, dyspnoea, and physiological...
Source: Respiratory Medicine CME - September 21, 2015 Category: Respiratory Medicine Authors: Arturo Cortés-Télles, Luis Torre-Bouscoulet, Monica Silva-Cerón, Roberto Mejía-Alfaro, Nafeez Syed, Gerald S. Zavorsky, Jordan A. Guenette Source Type: research
Development of chronic pulmonary aspergillosis in adult asthmatics with ABPA
Chronic pulmonary aspergillosis (CPA) is an occasional complication of allergic bronchopulmonaryaspergillosis (ABPA) but the transition is poorly understood. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 12, 2015 Category: Respiratory Medicine Authors: David Lowes, Livingstone Chishimba, Melanie Greaves, David W. Denning Source Type: research
Correlation of serum vascular endothelial growth factor-D concentration with clinical presentation and course of lymphangioleiomyomatosis
Increased serum vascular endothelial growth factor D (VEGF-D) concentration has been accepted as a diagnostic marker in lymphangioleiomyomatosis (LAM). The study was performed to evaluate the correlation of VEGF-D with clinical presentation and course of LAM. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 11, 2015 Category: Respiratory Medicine Authors: Elżbieta Radzikowska, Paulina Jaguś, Małgorzata Sobiecka, Joanna Chorostowska-Wynimko, Elżbieta Wiatr, Jan Kuś, Kazimierz Roszkowski-Śliż Source Type: research
Correlation of serum vascular endothelial growth factor –D concentration with clinical presentation and course of lymphangioleiomyomatosis
Increased serum vascular endothelial growth factor D (VEGF-D) concentration has been accepted as a diagnostic marker in lymphangioleiomyomatosis (LAM). The study was performed to evaluate the correlation of VEGF-D with clinical presentation and course of LAM. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 11, 2015 Category: Respiratory Medicine Authors: Elżbieta Radzikowska, Paulina Jaguś, Małgorzata Sobiecka, Joanna Chorostowska-Wynimko, Elżbieta Wiatr, Jan Kuś, Kazimierz Roszkowski- Śliż Source Type: research
Do asthma patients with panic disorder really have worse asthma? A comparison of physiological and psychological responses to a methacholine challenge
This study aimed to measure physiological and psychological responses to a simulated asthma attack (methacholine challenge test: MCT) in asthmatics with and without PD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 9, 2015 Category: Respiratory Medicine Authors: Maxine Boudreau, Kim L. Lavoie, André Cartier, Barbara Trutshnigg, Alexandre Morizio, Catherine Lemière, Simon L. Bacon Source Type: research
Right Ventricular Diastolic Function and Exercise Capacity in COPD
Decreased exercise capacity in chronic obstructive pulmonary disease (COPD) is incompletely explained by pulmonary pathologic and physiologic abnormalities. We evaluated the extent to which right ventricular diastolic function (RVDF) is associated with exercise capacity in COPD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 9, 2015 Category: Respiratory Medicine Authors: Brett E. Fenster, Kristen E. Holm, Howard D. Weinberger, Kerrie L. Moreau, Kimberly Meschede, James D. Crapo, Barry J. Make, Russell Bowler, Frederick S. Wamboldt, Karin F. Hoth Source Type: research
Hypersensitivity Pneumonitis and Antigen Identification – An Alternate Approach
Identification of the causal antigen for patients with hypersensitivity pneumonitis (HP) is challenging in a standard clinical setting. The purpose of this pilot study was to determine whether it was possible to evaluate the home/workplace of patients, and identify the causal antigen. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 8, 2015 Category: Respiratory Medicine Authors: M.L. Millerick-May, M.H. Mulks, J. Gerlach, K.R. Flaherty, S.L. Schmidt, F.J. Martinez, R.M. LeVeque, K.D. Rosenman Source Type: research
