Long term effect and allergic sensitization in newly employed workers in laboratory animal facilities
The aim of this study was to identify targets predicting allergic sensitization to laboratory animals using shift in skin prick test to laboratory animals as primary outcome variable. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - June 15, 2015 Category: Respiratory Medicine Authors: Lena Palmberg, Britt-Marie Sundblad, Anders Lindberg, Maciej Kupczyk, Karin Sahlander, Kjell Larsson Source Type: research
Focal pleural tumorlike conditions: nodules and masses beyond mesotheliomas and metastasis
A tumorlike condition of the pleura is any nonmalignant lesion of the pleura or within the pleural space that could be confused with a pleural tumor on initial imaging. Tumorlike conditions of the pleura are relatively rare compared with neoplastic lesions such as mesotheliomas and metastases. Imaging-based diagnosis of these conditions can be difficult due to the similarity of appearance. Thus, recognition of certain imaging patterns and interpretation of these patterns in the clinical context are important. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - June 13, 2015 Category: Respiratory Medicine Authors: Maria Clara Fernandes de Paula, Dante Luiz Escuissato, Luciana Camara Belém, Gláucia Zanetti, Arthur Soares Souza, Bruno Hochhegger, Luiz Felipe Nobre, Edson Marchiori Tags: Review article Source Type: research
Serum Metalloproteinases 1 and 7 in the Diagnosis of Idiopathic Pulmonary Fibrosis and Other Interstitial Pneumonias
Accurate diagnosis of idiopathic pulmonary fibrosis (IPF) has important therapeutic and prognostic implications and would be greatly aided by reliable diagnostic biomarkers as IPF has sometimes overlapping features with other interstitial lung diseases (ILD). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - June 13, 2015 Category: Respiratory Medicine Authors: António Morais, Marília Beltrão, Oksana Sokhatska, Diogo Costa, Natalia Melo, Patricia Mota, Agostinho Marques, Luís Delgado Source Type: research
The role of pulmonary arterial stiffness in COPD
COPD is the second most common cause of pulmonary hypertension, and is a common complication of severe COPD with significant implications for both quality of life and mortality. However, the use of a rigid diagnostic threshold of a mean pulmonary arterial pressure (mPAP) of ≥25mHg when considering the impact of the pulmonary vasculature on symptoms and disease is misleading. Even minimal exertion causes oxygen desaturation and elevations in mPAP, with right ventricular hypertrophy and dilatation present in patients with mild to moderate COPD with pressures below the threshold for diagnosis of pulmonary hypertension. (Sou...
Source: Respiratory Medicine CME - June 13, 2015 Category: Respiratory Medicine Authors: Jonathan R. Weir-McCall, Allan D. Struthers, Brian J. Lipworth, J Graeme Houston Tags: Review article Source Type: research
Efficacy and safety of umeclidinium added to fluticasone furoate/vilanterol in chronic obstructive pulmonary disease: results of two randomized studies
The aim of these studies (NCT01957163; NCT02119286) was to evaluate the efficacy and safety of umeclidinium (UMEC 62.5 μg and 125 μg) added to fluticasone furoate/vilanterol (FF/VI, 100/25 μg) in chronic obstructive pulmonary disease (COPD). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - June 13, 2015 Category: Respiratory Medicine Authors: Thomas M. Siler, Edward Kerwin, Ana R. Sousa, Alison Donald, Rehan Ali, Alison Church Source Type: research
