Novel Albuterol Multidose Dry Powder Inhaler in Patients With Exercise-Induced Bronchoconstriction: A Single-Dose, Double-Blind, Randomized, 2-Way Crossover Study
A novel, inhalation-driven, multidose dry powder inhaler (MDPI) was developed that eliminates the need to coordinate device actuation with inhalation as is required with conventional metered-dose inhalers. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 8, 2015 Category: Respiratory Medicine Authors: Nancy K. Ostrom, Herminia Taveras, Harald Iverson, David S. Pearlman Source Type: research
Corrigendum to “A randomized study of formoterol fumarate in a porous particle metered-dose inhaler in patients with moderate-to-severe COPD” [Resp Med 108 (2014) 1327–1335]
The authors regret that several errors occurred in the publication of the above-mentioned article. The errors are listed below: (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 7, 2015 Category: Respiratory Medicine Authors: Dean Quinn, J.P. Seale, Colin Reisner, Tracy Fischer, Michael Golden, Carlos Fernandez, Patrick Darken, Earl St. Rose, Mervyn Thomas, Gregory Tardie, Chadwick Orevillo Tags: Corrigendum Source Type: research
Editorial Board
(Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - September 1, 2015 Category: Respiratory Medicine Source Type: research
Characteristics of pulmonary complex disease diagnosed later in follow-up after negative mycobacterial study including bronchoscopy
We occasionally experience cases suspected of pulmonary Mycobacterium avium complex (MAC) disease without positive bacterial cultures. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 30, 2015 Category: Respiratory Medicine Authors: Kazuya Koyama, Nobuharu Ohshima, Masahiro Kawashima, Kenichi Okuda, Ryota Sato, Hideaki Nagai, Hirotoshi Matsui, Ken Ohta Source Type: research
The effect of body posture during medication inhalation on exercise induced bronchoconstriction in asthmatic children
This study investigated whether inhaling a single dose of ICS in a forward leaning posture improves this protection against EIB. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 28, 2015 Category: Respiratory Medicine Authors: Reina Visser, Mariet Wind, Beike J. de Graaf, Frans.H.C. de Jongh, Job van der Palen, Bernard.J. Thio Source Type: research
Impairments after curative intent treatment for non-small cell lung cancer: a comparison with age and gender-matched healthy controls
The aim of this study was to compare measures of exercise capacity, health-related quality of life (HRQoL), muscle force, lung function and feelings of anxiety and depression in people after curative intent treatment for NSCLC with age and gender-matched healthy controls. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 28, 2015 Category: Respiratory Medicine Authors: Vinicius Cavalheri, Sue Jenkins, Nola Cecins, Kevin Gain, Martin Phillips, Lucas H. Sanders, Kylie Hill Source Type: research
Letter to the Editor: “Risk factors for postoperative pneumonia after lung cancer surgery and impact of pneumonia on survival”
We have read with great interest the paper by Simonsen et al [1] on risk factors for postoperative pneumonia (POP) and the impact pneumonia has on survival of people after surgery for lung cancer. The authors stated in the conclusion paragraph that the presence of some risk factors for development of POP “may lead to specific prophylactic measures including individualised antibiotic therapy” [1]. Of note, preoperative exercise training was not mentioned as a prophylactic measure. It is well-known that preoperative exercise capacity (i.e. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 24, 2015 Category: Respiratory Medicine Authors: Vinicius Cavalheri, Kylie Hill Tags: Correspondence Source Type: research
Mayo clinic experience of lung transplantation in pulmonary lymphangioleiomyomatosis
Lymphangioleiomyomatosis (LAM) is a rare, cystic lung disease that generally results in progressive decline in lung function. Despite advancement of pharmacological therapy for LAM, lung transplantation remains an important option for women with end-stage LAM. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 24, 2015 Category: Respiratory Medicine Authors: Kamonpun Ussavarungsi, Xiaowen Hu, J.P. Scott, David B. Erasmus, Jorge M. Mallea, Francisco Alvarez, Augustine S. Lee, Cesar A. Keller, Jay H. Ryu, Charles D. Burger Source Type: research
Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients
Chronic obstructive pulmonary disease (COPD) is characterized by neutrophilic airway inflammation. Neutrophil extracellular trap (NET) formation - a meshwork of neutrophil DNA components and neutrophil enzymes are involved in innate immunity and inflammation. Little is known about the presence of these structures in induced sputum from stable COPD patients. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 21, 2015 Category: Respiratory Medicine Authors: Frauke Pedersen, Sebastian Marwitz, Olaf Holz, Anne Kirsten, Thomas Bahmer, Benjamin Waschki, Helgo Magnussen, Klaus F. Rabe, Torsten Goldmann, Mohib Uddin, Henrik Watz Tags: Short communication Source Type: research
The impact of birth weight on the level of lung function and lung function decline in the general adult population. The Inter99 study
Previous studies have reported an association between low birth weight and low adult lung function, but findings have not been consistent. The aim of this study was to investigate whether low birth weight is associated with both the level and the decline in adult lung function in general population. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 18, 2015 Category: Respiratory Medicine Authors: Sophie Baumann, Nina Skavlan Godtfredsen, Peter Lange, Charlotta Pisinger Source Type: research
Preoperative exercise therapy in lung surgery patients: a systematic review
The impact of postoperative complications after lung surgery for cancer is substantial, with the increasing age of patients and the presence of comorbidities. This systematic review summarises the effects of Preoperative Exercise Therapy (PET) in patients scheduled for lung surgery on aerobic capacity, physical fitness, postoperative complications, length of hospital stay, quality of life and recovery. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 15, 2015 Category: Respiratory Medicine Authors: Sjaak Pouwels, Jeroen Fiddelaers, Joep A.W. Teijink, Joost F.ter Woorst, Jan Siebenga, Frank W.J.M. Smeenk Tags: Review article Source Type: research
Survival in interstitial pneumonia with features of autoimmune disease: a comparison of proposed criteria
The objective of this study was to compare the clinical characteristics and behavior of each of the proposed diagnostic criteria. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 15, 2015 Category: Respiratory Medicine Authors: Deborah Assayag, Eunice J. Kim, Brett M. Elicker, Kirk D. Jones, Jeffrey A. Golden, Talmadge E. King, Laura L. Koth, Anthony K. Shum, Paul J. Wolters, Harold R. Collard, Joyce S. Lee Source Type: research
Efficacy of a New Intravenous β-adrenergic Agonist (Bedoradrine, MN-221) for Patients with an Acute Exacerbation of Asthma
Many patients with acute exacerbation of asthma are non-responders to inhaled β-adrenergic agonists. The goal of this study was to evaluate the safety and efficacy of intravenous bedoradrine (MN-221), a highly selective β2-adrenergic agonist, as adjunct to standard therapy in the management of patients with acute exacerbation of asthma who did not respond to standard therapy. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 14, 2015 Category: Respiratory Medicine Authors: Stacey L. House, Kazuko Matsuda, Geoffrey O’Brien, Malath Makhay, Yuichi Iwaki, Ian Ferguson, Luis M. Lovato, Lawrence M. Lewis Tags: Clinical Trial Paper Source Type: research
Tiotropium + olodaterol shows clinically meaningful improvements in quality of life
Tiotropium + olodaterol improves lung function and symptoms compared to monotherapies in chronic obstructive pulmonary disease (COPD). The OTEMTO 1 and 2 studies investigated the effects of tiotropium + olodaterol on lung function and health-related quality of life compared to placebo in patients with moderate to severe COPD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 12, 2015 Category: Respiratory Medicine Authors: Dave Singh, Gary T. Ferguson, Josef Bolitschek, Lars Grönke, Christoph Hallmann, Nathan Bennett, Roger Abrahams, Olaf Schmidt, Leif Bjermer Source Type: research
Tiotropium+olodaterol shows clinically meaningful improvements in quality of life
Tiotropium+olodaterol improves lung function and symptoms compared to monotherapies in chronic obstructive pulmonary disease (COPD). The OTEMTO 1 and 2 studies investigated the effects of tiotropium+olodaterol on lung function and health-related quality of life compared to placebo in patients with moderate to severe COPD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 12, 2015 Category: Respiratory Medicine Authors: Dave Singh, Gary T. Ferguson, Josef Bolitschek, Lars Grönke, Christoph Hallmann, Nathan Bennett, Roger Abrahams, Olaf Schmidt, Leif Bjermer Source Type: research
