Capnometry in children with bronchiolitis: A pathophysiological point of view
Bronchiolitis is the most common lower respiratory tract infection among infants and young children [1]. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 6, 2016 Category: Respiratory Medicine Authors: Jacopo Colombo, Alfio Bronco, Valeria Lippolis, Ezio Bonanomi Tags: Correspondence Source Type: research
Impact of angiopoietin-1 and -2 on clinical course of idiopathic pulmonary fibrosis
Angiopoietin (Ang) -1 and -2 are glycoproteins that play roles in vascular development, angiogenesis, and lung vascular permeability. Although the serum concentrations of Ang-1 and -2 have been evaluated in patients with sepsis, those in patients with idiopathic pulmonary fibrosis (IPF) have received less attention. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 5, 2016 Category: Respiratory Medicine Authors: Masahiro Uehara, Noriyuki Enomoto, Masashi Mikamo, Yoshiyuki Oyama, Masato Kono, Tomoyuki Fujisawa, Naoki Inui, Yutaro Nakamura, Takafumi Suda Source Type: research
Effect of tiotropium on COPD exacerbations: A systematic review
Exacerbation frequency is related to disease progression, quality of life, and prognosis in COPD. Earlier diagnosis, along with interventions aimed at preventing exacerbations and delaying progression, may help reduce the global burden of disease. Long-acting inhaled bronchodilators are effective at maintaining symptom relief and are recommended as first-choice therapy for more symptomatic patients and those at risk of exacerbation. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 1, 2016 Category: Respiratory Medicine Authors: David M.G. Halpin, Claus Vogelmeier, Michael P. Pieper, Norbert Metzdorf, Frank Richard, Antonio Anzueto Tags: Review article Source Type: research
Is capnometry helpful in children with bronchiolitis?
Acute bronchiolitis is the most frequent lower respiratory tract infection in infants. Only small subsets of patients develop severe disease resulting in hospitalization despite having no identifiable risk factors. There is still a debate as to the role of capnometry in assessing ventilation in children with acute respiratory distress, and bronchiolitis in particular. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 24, 2016 Category: Respiratory Medicine Authors: Ron Jacob, Lea Bentur, Riva Brik, Itai Shavit, Fahed Hakim Source Type: research
Maternal and perinatal outcomes of pregnancies in women with cystic fibrosis – A single centre case-control study
Due to increased survival, more women with cystic fibrosis become pregnant. However, studies on the specificities of pregnancy in CF versus healthy women are lacking. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 23, 2016 Category: Respiratory Medicine Authors: Aude Girault, Julie Blanc, Vanessa Gayet, François Goffinet, Dominique Hubert Source Type: research
Maternal and perinatal outcomes of pregnancies in women with cystic fibrosis -a single centre case-control study
Due to increased survival, more women with cystic fibrosis become pregnant. However, studies on the specificities of pregnancy in CF versus healthy women are lacking. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 23, 2016 Category: Respiratory Medicine Authors: Aude Girault, Julie Blanc, Vanessa Gayet, François Goffinet, Dominique Hubert Source Type: research
The three tiers of screening for sarcoidosis organ involvement
Sarcoidosis may involve any organ in the body. Organ involvement with sarcoidosis may go undetected. This manuscript addresses a suggested approach to screening for sarcoidosis organ involvement. As sarcoidosis organ involvement may never cause symptoms or clinical problems, it is not always necessary to expend the time or expense to detect all organs involved with sarcoidosis. On the other hand, some forms of sarcoidosis organ involvement may have potentially severe consequences such as permanent vision impairment from eye sarcoidosis and sudden death from cardiac sarcoidosis. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 23, 2016 Category: Respiratory Medicine Authors: Marc A. Judson Tags: Review article Source Type: research
Asthma control and cold weather-related respiratory symptoms
In the northern hemisphere people are exposed recurrently to cold air and asthmatics experience more respiratory symptoms. We hypothesized that subjects with poor asthma control are more prone to experience cold weather-related respiratory symptoms than those with good asthma control. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 22, 2016 Category: Respiratory Medicine Authors: Henna Hyrkäs, Tiina M. Ikäheimo, Jouni J.K. Jaakkola, Maritta S. Jaakkola Source Type: research
Exhaled nitric oxide as a diagnostic tool for wheezing in preschool children: A diagnostic accuracy study
This study aimed to determine the accuracy of FENO in identifying wheezing in preschoolers. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 21, 2016 Category: Respiratory Medicine Authors: Larissa Bouwman Sayão, Murilo Carlos Amorim de Britto, Edjane Burity, Catarina Rattes, Cyda Maria Albuquerque Reinaux, James Fink, Armèle Dornelas de Andrade Source Type: research
Whistle and cough pressures in children with neuromuscular disorders
Expiratory muscle strength is a determinant of cough function. Maximal static expiratory pressure (PEmax) manoeuvres are widely used but are limited by patient motivation and technique. The study hypothesized that whistle mouth (PmW) and cough gastric (PgasCough) pressures might provide additional tests of expiratory muscle strength in children and young adults with neuromuscular disease (NMD). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 21, 2016 Category: Respiratory Medicine Authors: Sabrina Aloui, Sonia Khirani, Adriana Ramirez, Marina Colella, Bruno Louis, Alessandro Amaddeo, Brigitte Fauroux Source Type: research
Adverse events among COPD patients treated with long-acting anticholinergics and β2-agonists in an outpatient respiratory clinic
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in Canada. Most patients with COPD receive long-term treatment with long-acting anticholinergics (LAAC) and/or long-acting β2-agonists (LABA). Adverse events (AEs) are also likely during long-term treatment with these medications. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 17, 2016 Category: Respiratory Medicine Authors: Claudie Rodrigue, Marie-France Beauchesne, François Savaria, Amélie Forget, Catherine Lemière, Pierre Larivée, Lucie Blais, for the RESP Investigators Source Type: research
Effects on Pulmonary Rehabilitation in Patients with COPD or ILD: A Retrospective Analysis of Clinical and Functional Predictors with Particular Emphasis on Gender
The response of patients in a pulmonary rehabilitation (PR) is essentially good. However, not all patients benefit from PR to the same extent. In this analysis we wanted to identify the impact of gender and other factors on PR outcomes in patients with chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 16, 2016 Category: Respiratory Medicine Authors: M. Spielmanns, R. Gloeckl, C. Schmoor, W. Windisch, J.H. Storre, M. Boensch, K. Kenn Source Type: research
Klotho and smoking – An interplay influencing the skeletal muscle function deficits that occur in COPD
The objective of this study was to evaluate skeletal muscle and circulating Klotho protein in smokers and COPD patients and to relate Klotho levels to relevant skeletal muscle parameters. We sought to validate our findings by undertaking complimentary murine studies. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 15, 2016 Category: Respiratory Medicine Authors: M.S. Patel, A.V. Donaldson, A. Lewis, S.A. Natanek, J.Y. Lee, Y.M. Andersson, G. Haji, S.G. Jackson, B.J. Bolognese, J.P. Foley, P.L. Podolin, P.L.B. Bruijnzeel, N. Hart, N.S. Hopkinson, W.D.-C. Man, P.R. Kemp, M.I. Polkey Source Type: research
Klotho and smoking - An interplay influencing the skeletal muscle function deficits that occur in COPD
The objective of this study was to evaluate skeletal muscle and circulating Klotho protein in smokers and COPD patients and to relate Klotho levels to relevant skeletal muscle parameters. We sought to validate our findings by undertaking complimentary murine studies. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 15, 2016 Category: Respiratory Medicine Authors: M.S. Patel, A.V. Donaldson, A. Lewis, S.A. Natanek, J.Y. Lee, Y.M. Andersson, G. Haji, S.G. Jackson, B.J. Bolognese, J.P. Foley, P.L. Podolin, P.L.B. Bruijnzeel, N. Hart, N.S. Hopkinson, W. D-C Man, P.R. Kemp, M.I. Polkey Source Type: research
Lung function decline over 25 years of follow-up among black and white adults in the ARIC study cohort
Interpretation of longitudinal information about lung function decline from middle to older age has been limited by loss to follow-up that may be correlated with baseline lung function or the rate of decline. We conducted these analyses to estimate age-related decline in lung function across groups of race, sex, and smoking status while accounting for dropout from the Atherosclerosis Risk in Communities Study. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 11, 2016 Category: Respiratory Medicine Authors: Maria C. Mirabelli, John S. Preisser, Laura R. Loehr, Sunil K. Agarwal, R. Graham Barr, David J. Couper, John L. Hankinson, Noorie Hyun, Aaron R. Folsom, Stephanie J. London Source Type: research
