Bulletin of Faculty of Pharmacy, Cairo University 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Enhanced photocatalytic –biological degradation of 2,4 dichlorophenoxyacetic acid
In this study the most effective method of its degradation and bioremediation has been studied. Two microbial consortia capable of utilizing 2,4-D as a sole source of carbon were isolated from the Egyptian environment. One of the microbial consortia interestingly contained a certain kind of protozoa as one of the mixed consortia members. Degradation of 2,4-D by the microbial consortia was affected by 2,4-D initial concentration, agitation, pH of the medium and temperature. The two consortia were able to degrade up to 700mgl−1 of 2,4-D. Pre-treatment with UV radiations in the presence of photocatalyst such as TiO2 acceler...
Source: Bulletin of Faculty of Pharmacy, Cairo University - July 20, 2016 Category: Drugs & Pharmacology Source Type: research
LC and LC –MS study for simultaneous determination of tramadol hydrochloride and ketorolac tromethamine in bulk and formulation with their major degradation products
Publication date: June 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University, Volume 54, Issue 1 Author(s): Vrushali S. Tambe, M.N. Deodhar, Vijayalakshmi Prakya The present work was aimed to separate, identify and characterize the major degradation products of tramadol hydrochloride and ketorolac tromethamine. A rapid, specific and accurate stability indicating reversed phase liquid chromatographic method has been developed for simultaneous determination of tramadol hydrochloride and ketorolac tromethamine in bulk and formulation. The drugs were subjected to hydrolysis (acidic, alkaline and neutral), oxi...
Source: Bulletin of Faculty of Pharmacy, Cairo University - July 20, 2016 Category: Drugs & Pharmacology Source Type: research
The potential effects of Melicope ptelefolia root extract as an anti-nociceptive and anti-inflammatory on animal models
In conclusion, methanol root extract of M. ptelefolia possesses anti-inflammatory effects and anti-nociceptive effects in rats. (Source: Bulletin of Faculty of Pharmacy, Cairo University)
Source: Bulletin of Faculty of Pharmacy, Cairo University - July 16, 2016 Category: Drugs & Pharmacology Source Type: research
Response surface based co-optimization of release kinetics and mucoadhesive strength for an oral mucoadhesive tablet of cefixime trihydrate
Conclusion Cefixime trihydrate can be effectively formulated as an oral controlled release mucoadhesive tablet using RSM, and it is possible to achieve adequate mucoadhesive strength and the desired release profile with the optimum combination of polymers. Graphical abstract (Source: Bulletin of Faculty of Pharmacy, Cairo University)
Source: Bulletin of Faculty of Pharmacy, Cairo University - July 9, 2016 Category: Drugs & Pharmacology Source Type: research
Comparative study of the volatile oil content and antimicrobial activity of Psidium guajava L. and Psidium cattleianum Sabine leaves
Publication date: Available online 1 July 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Fathy M. Soliman, Magda M. Fathy, Maha M. Salama, Fatema R. Saber The chemical composition of the hydrodistilled oils of the leaves of Psidium guajava L. (guava leaf) and Psidium cattleianum Sabine (strawberry guava) was determined by GC/MS analysis to identify their chemotypes. Moreover, in vitro antimicrobial activity of these volatile oils against selected bacteria, yeast, and mycelia fungi was studied. The yield of the volatile oil hydrodistilled from the leaves of P. guajava L. and P. cattleia...
Source: Bulletin of Faculty of Pharmacy, Cairo University - July 1, 2016 Category: Drugs & Pharmacology Source Type: research
Adenine and benzimidazole-based mimics of REP-3123 as antibacterial agents against Clostridium difficile and Bacillus anthracis: Design, synthesis and biological evaluation
Publication date: Available online 29 June 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Ahmed G. Eissa, James A. Blaxland, Rhodri O. Williams, Kamel A. Metwally, Sobhy M. El-Adl, El-Sayed M. Lashine, Leslie W.J. Baillie, Claire Simons As part of our ongoing research efforts to develop new antibacterial agents acting on novel molecular targets, a series of twenty-two adenine and benzimidazole-based mimics of the lead compound REP-3123 was designed to target methionyl-tRNA synthetase of Clostridium difficile and Bacillus anthracis based on a homology model. Structures of the ta...
Source: Bulletin of Faculty of Pharmacy, Cairo University - June 29, 2016 Category: Drugs & Pharmacology Source Type: research
Hepatoprotective, anti-inflammatory and antioxidant activities of Flacourtia montana J. Grah leaf extract in male Wistar rats
Publication date: Available online 21 June 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Chinchu Joshy, P.A. Thahimon, R. Arun Kumar, Betty Carla, Christudas Sunil Flacourtia montana and its related species have been used traditionally for the treatment of various diseases. The present study evaluated the hepatoprotective, anti-inflammatory and antioxidant activities of F. montana methanolic extract. The hepatoprotective effect of F. montana was evaluated against paracetamol induced hepatotoxicity in Wistar rats. Administration of paracetamol (2g/kg) showed a significant biochemica...
Source: Bulletin of Faculty of Pharmacy, Cairo University - June 21, 2016 Category: Drugs & Pharmacology Source Type: research
Perceptions of Egyptian physicians about drug shortage during political disturbances: Survey in Greater Cairo
Conclusion Prospective studies are required to quantitatively estimate drug shortage related mortality. Enhanced drug shortage communication by drug authorities and targeted education may relieve inter-professional conflicts resulting from drug shortages. (Source: Bulletin of Faculty of Pharmacy, Cairo University)
Source: Bulletin of Faculty of Pharmacy, Cairo University - June 10, 2016 Category: Drugs & Pharmacology Source Type: research
Development and validation of stability indicating TLC densitometric and spectrophotometric methods for determination of Clobetasol propionate
Publication date: Available online 6 June 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Yasmine Farouk Bassuoni, Eman Saad Elzanfaly, Hebatallah Mohamed Essam, Hala El-Sayed Zaazaa Two simple analytical techniques that manipulate the inherent spectroscopic properties of the drug differently were developed for Clobetasol propionate (CP) determination in the presence of its alkaline hydrolytic degradation products. The first method depends on TLC-densitometric determination of the UV–visualized bands after TLC separation of CP in the presence of its alkaline degradation products in it...
Source: Bulletin of Faculty of Pharmacy, Cairo University - June 6, 2016 Category: Drugs & Pharmacology Source Type: research
Validated spectrometric determination of penciclovir and entecavir in bulk and in pharmaceutical preparations
Publication date: Available online 6 June 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Asmaa A. Elzaher, Marwa A. Fouad, Ola M. Elhoussini, Yasmine Essam-Eldin Behery Simple, rapid and sensitive spectroscopic methods were developed and validated for the determination of antiviral agents, namely, penciclovir (PCV) and entecavir (ETV). The first method is based on measuring the native fluorescence of each of the cited drugs at its optimum excitation and emission wavelengths. The fluorescence intensity was measured for PCV & ETV at 363nm and 370nm upon excitation at 260nm and 25...
Source: Bulletin of Faculty of Pharmacy, Cairo University - June 5, 2016 Category: Drugs & Pharmacology Source Type: research
Simple spectrophotometric methods for the simultaneous determination of antipyrine and benzocaine
Publication date: Available online 2 June 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Hanan A. Merey Antipyrine and benzocaine are formulated together for the treatment of ear inflammation and to relieve pain. Four spectrophotometric methods were developed for the simultaneous determination of antipyrine (AN) and benzocaine (BE) in their combined dosage form. Method A depends on applying dual wavelength method where antipyrine was determined by measuring the absorbance at 254.1 and 309.1nm (corresponding to zero difference of benzocaine), while the absorbance difference at 230.1 and 263.5...
Source: Bulletin of Faculty of Pharmacy, Cairo University - June 2, 2016 Category: Drugs & Pharmacology Source Type: research
A validated inherent stability indicating HPTLC method for estimation of cyclobenzaprine hydrochloride in tablets and use of MS–QTOF in characterization of its alkaline stress degradation product
Publication date: Available online 20 May 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Minal T. Harde, Sagar B. W.hede, Praveen D. Chaudhari A simple, selective and sensitive stability indicating high-performance thin-layer chromatographic method was developed and validated for estimation of cyclobenzaprine hydrochloride (CBP) in bulk drug and commercial tablets according to ICH guidelines. A precoated silica gel 60F254 HPTLC plates were used for chromatographic separation using mobile phase toluene: ethyl acetate: methanol: glacial acetic acid in the ratio 4:2:3.5:0.5 v/v/v/v. A TLC s...
Source: Bulletin of Faculty of Pharmacy, Cairo University - May 20, 2016 Category: Drugs & Pharmacology Source Type: research
A pharmacokinetic study of digoxin holiday dosing practice in Egypt: A prospective-randomized trial
Conclusion Once daily tablet (0.25mg) was suitable in maintaining digoxin serum concentration in the recommended therapeutic range, fluctuation in digoxin serum concentration did not affect quality of life for atrial fibrillation patients. (Source: Bulletin of Faculty of Pharmacy, Cairo University)
Source: Bulletin of Faculty of Pharmacy, Cairo University - May 13, 2016 Category: Drugs & Pharmacology Source Type: research
Effect of Amlodipine, Cilnidipine and Diltiazem on lipid profiles of hypertensive rats fed with high fat diet: A comparative study
Conclusion These results indicate that they have a lipid lowering effect due to effect on different stages of metabolism of lipids. (Source: Bulletin of Faculty of Pharmacy, Cairo University)
Source: Bulletin of Faculty of Pharmacy, Cairo University - May 10, 2016 Category: Drugs & Pharmacology Source Type: research
LC and LC–MS study for simultaneous determination of tramadol hydrochloride and ketorolac tromethamine in bulk and formulation with their major degradation products
Publication date: Available online 22 February 2016 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Vrushali S. Tambe, M.N. Deodhar, Vijayalakshmi Prakya The present work was aimed to separate, identify and characterize the major degradation products of tramadol hydrochloride and ketorolac tromethamine. A rapid, specific and accurate stability indicating reversed phase liquid chromatographic method has been developed for simultaneous determination of tramadol hydrochloride and ketorolac tromethamine in bulk and formulation. The drugs were subjected to hydrolysis (acidic, alkaline and neutral),...
Source: Bulletin of Faculty of Pharmacy, Cairo University - February 23, 2016 Category: Drugs & Pharmacology Source Type: research
