Matrix Gla Protein in relation to left ventricular diastolic function
Introduction: Matrix Gla Protein (MGP) is highly expressed in cardiomyocytes and is upregulated after acute and chronic pressure overload and in myocardial hypertrophy in mice and humans. However, no study addressed the relation between cardiac function and MGP in humans. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Thibault Petit, Zhen-Yu Zhang, Wen-Yi Yang, Fang-Fei Wei, Yu-Mei Gu, Juditha Knez, Nicholas Cauwenberghs, Yan-Ping Liu, Nadja Drummen, Lotte Jacobs, Lutgarde Thijs, Tatiana Kuznetsova, Stefan Janssens, Cees Vermeer, Jan A. Staessen Source Type: research
Measurement of arterial stiffness by ultrafast echo: Comparison with echotracking in normotensive subjects and hypertensive patients
Because measurement of arterial stiffness is highly dependent on blood pressure (BP), methods independent of BP are required. Ultrafast echography (UFE, Supersonic Imagine, Aix en Provence, France) makes use of very fast sampling rate (up to 10 kHz), so transient events such as pressure wave arrival can be tracked. This method has never been tested against classical echotracking (Artlab, Esaote, Maastricht, NL) and carotid-femoral pulse wave velocity (cf-PWV, Sphygmocor, AtCor, Sydney, Australia). (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Louise Marais, Mathieu Pernot, Hakim Khettab, Mickael Tanter, Emmanuel Messas, Mustapha Zidi, Stéphane Laurent, Pierre Boutouyrie Source Type: research
Association between endogenous serum testosterone concentrations and aortic pressures and pulse wave amplification indices in erectile dysfunction patients
Purpose: Erectile dysfunction (ED) is an independent predictor of future cardiovascular (CV) events. Aortic pressures (central) and low testosterone independently predict future CV events and mortality. The relationship between testosterone, central pressures and wave reflection indices in ED patients is unknown. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Nikolaos Ioakeimidis, Panagiota Pietri, Athanassios Angelis, Ioanna Gourgouli, Christos Georgakopoulos, Christodoulos Stefanadis, Dimitrios Tousoulis Source Type: research
Vascular adaptation to extreme conditions: The role of hypoxia
Abstract (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Rosa Maria Bruno, Lorenzo Ghiadoni, Lorenza Pratali Source Type: research
Circadian blood pressure profile and target organ damage
Abstract (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Agnieszka Bednarek Source Type: research
Aldosteronism, heart and vessels
It has been documented that absolute aldosterone excess in patients with primary aldosteronism (PA) has been associated with higher risk of heart, vascular and kidney damage independent on blood pressure and resulting in increased total cardiovascular risk. Structural (left ventricular hypertrophy) and functional (diastolic dysfunction) changes of the heart have been documented in patients with PA. We have shown that patients with resistant hypertension and PA are characterized by higher prevalence of left ventricular hypertrophy than patients with resistant hypertension without PA. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Aleksander Prejbisz Source Type: research
What is the best method to evaluate retinal microcirculation?
The microvasculature of retinal ganglion cell layer, which is the part of central nervous system, can be investigated non-invasively in human. For clinical routine the fluorescence angiography is used to test patency and leak of retinal or choroid vessels, and to determine the blood passage time through the capillaries, but not to measure microperfusion. The first non-mydriatic Heidelberg Retina Flowmetry with Scanning Laser Doppler Flowmetry (SLDF) technology using perfusion image analysis software AFFPIA has enabled simultaneously reliable examination of retinal microperfusion (RCF) and arteriolar morphology (inner and o...
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Joanna Harazny Source Type: research
Retinal arteriolar structure in primary hypertension – Review of the data
Vascular dysfunction and remodelling due to elevated blood pressure constitutes an early step in the pathogenesis of atherosclerotic disease. Microvascular remodelling reduces tissue perfusion and impedes blood-tissue exchange. These processes could lead to inadequate perfusion and tissue hypoxia in situations of high metabolic demand. Impaired tissue perfusion may be involved in target-organ damage and complications that involve several vascular beds. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Andrzej Januszewicz Source Type: research
Sodium intake in relation to cardiovascular outcome
Abstract (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Katarzyna Stolarz-Skrzypek Source Type: research
Physical activity is associated with flow-mediated dilatation in females
Impairment of vascular endothelial function is an early sign of atherosclerosis. An active lifestyle is suggested to be positively associated with favorable endothelial function as opposed to a sedentary lifestyle. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Ulrika Ferberg, Katya Matusevich, Gabriella Eliason, Maria Fernstom, Anita Hurtig-Wennlof Source Type: research
Nanomechanical alterations in the adventitial layer of the internal mammary artery of patients with high PWV
This study compared localised differences in the nano-structure and mechanical properties in the internal mammary arteries (IMA) from patients with high and low PWV. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Zhuo Chang, Maria Lyck Hansen, Lars Melholt Rasmussen, Riaz Akhtar Source Type: research
A new dynamic organ bath setup to assess isobaric stiffness parameters of periodically stretched isolated mouse aortic segments
Cyclic stretch is a major contributor of vascular function. However, isolated mouse aortas are frequently studied at low stretch frequency or even isometric conditions. Pacing experiments done in rodents and humans show that arterial compliance is highly cyclic stretch frequency-dependent. The Rodent Oscillatory Tension Set-up to study Arterial Compliance (ROTSAC) is an in-house developed organ bath that clamps aortic segments (width 2mm, diameter 0.5-3mm) to imposed preloads at physiological rates up to 600bpm. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Arthur J.A. Leloup, Cor E. Van Hove, Guido R.Y. De Meyer, Dorien M. Schrijvers, Gilles W. De Keulenaer, Paul Fransen Source Type: research
Hemodynamics of pulmonary hypertension: Application of the reservoir-wave approach
Using the reservoir-wave approach, previously we characterized pulmonary vasculature mechanics with multiple interventions in a canine model. In the present study, we measured high-fidelity pulmonary arterial (PA) pressure, Doppler flow velocity, and pulmonary capillary wedge pressure in 11 patients referred for evaluation of exertional dyspnea. The analysis was performed using the reservoir-wave approach; wave intensity analysis was subsequently utilized to characterize the PA wave pattern. Our objective was to identify specific abnormalities associated with pulmonary hypertension. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Anukul Ghimire, Mads Andersen, Lindsay Burrowes, J. Christopher Bouwmeester, Andrew Grant, Israel Belenkie, Nowell Fine, Barry Borlaug, John Tyberg Source Type: research
Age and hypertension strongly reduce aortic visco-elastic properties in rats at basal and matched blood pressure levels
Age and hypertension are major causes of large artery stiffening, a cardiovascular risk factor for heart and kidney damage. Long term hypertension induces vascular remodeling, accelerating vascular aging. The aged Spontaneously Hypertensive Rat (SHR) model is recognized for human cardiovascular pathology but discrepancies are apparent in studies of arterial stiffness. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: George Lindesay, Christophe Ragonnet, Stefano Chimenti, Nicole Villeneuve, Christine Vayssettes-Courchay Source Type: research
Development of a technique for determination of pulmonary artery pulse wave velocity in horses
This study aimed to develop a technique for determination of pulse wave velocity of the main pulmonary arteries of horses. (Source: Artery Research)
Source: Artery Research - November 24, 2015 Category: Cardiology Authors: Gonçalo Silva, Bruce Guest, Diego Gomez, Martine McGregor, John Runciman, Luis Arroyo Source Type: research
