Association of a new surrogate of total arterial compliance with left ventricular mass: the SAFAR study
We investigated the association of total arterial compliance (CT) with left ventricular mass (LVM) and hypertrophy (LVH). The study hypothesis was that CT may be better related with LVM compared to the gold-standard regional aortic stiffness. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Theodore Papaioannou, Athanase Protogerou, Antonis Argyris, Evangelia Aissopou, Eftymia Nasothymiou, Christos Tountas, Petros Sfikakis, Nikolaos Stergiopulos, Dimitrios Tousoulis Source Type: research

Influence of the pressure measuring site for velocity/pressure loops
Background: Velocity/pressure (Vel/P) loops are obtained by combining aortic blood velocity (measured by esophageal Doppler-ED-, CombiQ ™, Deltex Medical, Chichester, UK) and arterial pressure signals. They represent a tool to estimate afterload of the heart and arterial stiffness with at least two remarkable angles: β and γ. Pressure is usually measured in the radial artery (PRad) rather than in the descending thoracic aorta (P AoDesc) where ED measures blood flow. Our aims were to assess the influence of the site of pressure recording on the values of β and γ and to develop a mathematical transfer function (TF) to ...
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Jona Joachim, Fabrice Vall ée, Arthur Le Gall, Stéphanie Lenck, Alexandre Mebazaa, Étienne Gayat Source Type: research

Study of wave dynamics of an extra-aortic counterpulsation device in a one-dimensional computer model of the arterial system
Background: The C-Pulse heart assist system (Sunshine Heart, Inc., Eden Prairie, Minnesota) is a novel extra-aortic counterpulsation device to unload the heart in heart failure patients. Its impact on overall hemodynamics, however, is not fully understood. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Daime Campos Arias, Francisco Londono, Tania Rodriguez Moliner, Dimitrios Georgakopoulos, Nikos Stergiopulos, Patrick Segers Source Type: research

An extended one-dimensional arterial network model for the simulation of pressure and flow in upper and lower limb extremities
Background: Arterial pulse wave velocity and pulse waveform analysis have become an established component of cardiovascular research. As validation and assessment of devices is not always trivial in an in vivo setting, arterial network computer models may be useful for that purpose. It is, however, mandatory that the model includes sufficient detail, especially when analysing peripheral waveforms. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Hasan Obeid, Patrick Segers, Nikos Stergiopulos, Pierre Boutouyrie, Stephane Laurent, Magid Hallab, Elie Mousseaux Source Type: research

Modelling arterial pulse pressure from heart rate during sympathetic activation
Background: The duration of the time segment between the systolic (SP) and post-dicrotic notch peak pressures (PDP) of the arterial pressure wave in humans has been proposed to be related to arterial pulse pressure (PP).1,2 We considered an effect of RR-interval length on the diastolic pressure run-off and tested the hypothesis that heart rate (HR) affects the timing of systolic and post-dicrotic notch peak pressures. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Bjorn van der Ster, Berend Westerhof, Wim Stok, Feras Hatib, Jos Settels, Johannes van Lieshout Source Type: research

Form factor of the femoral artery: an invasive study
Background: There is a growing interest in precisely estimating mean blood pressure (MBP) in large arteries. The form factor (FF) is the fraction of pulse pressure that must be added to diastolic pressure to estimate the actual MBP, i.e., the pressure integrated (averaged) over the whole cycle. It is admitted that FF of the radial artery is 0.33, while FF of the aorta and carotid and brachial arteries is in the 0.40-0.45 range. The FF of the femoral artery remains to be determined. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Mathieu Jozwiak, Sandrine Millasseau, Xavier Monnet, Francois Depret, Jean-Emmanuel Alphonsine, Nathalie Richard, Pierre Attal, Jean-Louis Teboul, Denis Chemla Source Type: research

Towards noninvasive cardiac catheterisation
Background: Doppler echocardiographic measures of diastolic function, such as E/e ’ are correlates of left ventricular (LV) end-diastolic pressure (ped) and diastolic compliance (Cd) [1]. We developed a noninvasive computational approach to obtain these essential markers of LV diastolic abnormalities and tested it against the invasive gold standard. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Maarten Heusinkveld, Joost Lumens, Katherine March, Arthur Bouwman, Tammo Delhaas, Alun Hughes, Koen Reesink Source Type: research

Remodelling small arteries and PhD training: A journey
Abstract (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Michael J. Mulvany Source Type: research

Stem cell therapy for cardiovascular diseases
Abstract (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Jean Sebastien Silvestre Source Type: research

Arterial proteomics: Lessons in relation to stiffness, aneurysms, diabetes and other conditions
Abstract (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Lars Melholt Rasmussen Source Type: research

Wave potential: A unified model of arterial waves, reservoir phenomena and their interaction
Abstract (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Jonathan P. Mynard, Joseph J. Smolich Source Type: research

Vascular dysfunction: At the heart of cardiovascular disease, cognitive impairment and depressive symptoms
Vascular dysfunction may be an important pathway through which ageing and other factors, such as diabetes and obesity, can cause diseases of the heart and brain. Vascular dysfunction includes dysfunction of large arteries (due to arterial stiffness), the microcirculation (microvascular dysfunction) and endothelium (endothelial dysfunction). We have investigated, in a series of epidemiological studies, the role of vascular dysfunction in the pathogenesis of cardiovascular disease, dementia and depression. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Thomas van Sloten Source Type: research

Arterial inflammation, blood pressure and central hemodynamics – The ABC of diabetic angiopathy
Aim: In diabetes patients, we explored relationships between markers of diabetic angiopathy, diabetic complications and adverse outcome. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Simone Theilade Source Type: research

Why does non-alcoholic fatty liver disease (NAFLD) contribute to cardiovascular outcomes?
Take home messages (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Hannele Yki-J ärvinen Source Type: research

Constituent based modelling of arterial wall mechanics
Abstract (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Lydia Aslanidou, Rodrigo Araujo Fraga da Silva, Patrick Segers, Nikos Stergiopulos Source Type: research