Rebound weight gain and blood pressure control after living kidney donation and kidney transplantation
Objective: Overweight and obesity are known risk factors of hypertension in both donors and recipients after kidney donation and transplantation, respectively. We aim to study the correlation between blood pressure (BP) and body mass index (BMI) in donor post-donation and in recipients post-transplantation. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Ekamol Tantisattamo, Weera Sukhumthammarat, Prapaipan Putthapiban, Wasawat Vutthikraivit, Siwadon Pitukweerakul Source Type: research
Central hemodynamics and arterial stiffness in young obese adults: The preliminary finding
Changes in central hemodynamics and arterial stiffness are associated with augmented cardiovascular risks and have been reported in obese adults with metabolic syndrome. It is unclear whether this observation may also be present in young healthy obese adults with normal metabolic profile. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: K. Bunsawat, G. Grigoriadis, T. Hilgenkamp, B. Fernhall, T. Baynard Source Type: research
Vascular function in individuals with Down syndrome
Individuals with Down syndrome (DS) experience premature aging. Arterial stiffness increases with advancing biological age and predicts cardiovascular disease. However, only limited studies investigated arterial function in individuals with DS. Thus, the impact of DS on vascular function still remains poorly understood. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Sang Ouk Wee, Alexander J. Rosenberg, Kanokwan Bunsawat, Garett Griffith, Tracy Baynard, Bo Fernhall Source Type: research
Multiple sclerosis patients experience more decrements in carotid artery functional properties with aging than age-matched peers
Introduction: Peak prevalence of multiple sclerosis (MS) is approaching 60 years of age, suggesting an aging patient population compared to past reports. Aging is independently associated with increased cardiovascular disease risk. Additionally, arterial function is compromised with aging. Carotid artery stiffness serves as a non-invasive method to quantify aspects of arterial function. As MS patients increase their average lifespan, it is unclear if they may experience differential changes in aspects of carotid artery function compared to their healthy age-matched peers. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Garett Griffith, Thessa Hilgenkamp, Rachel E. Klaren, Sang Ouk Wee, Robert W. Motl, Tracy Baynard, Bo Fernhall Source Type: research
Relations between aortic stiffness and left ventricular mechanical function
In this study, we investigated the relation between aortic stiffness and GLS in a large community-based sample. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Vanessa C. Bell, Elizabeth L. McCabe, Martin G. Larson, Jian Rong, Allison A. Merz, Ewa Osypiuk, Birgitta T. Lehman, Plamen Stantchev, Jayashri Aragam, Emelia J. Benjamin, Naomi M. Hamburg, Ramachandran S. Vasan, Gary F. Mitchell, Susan Cheng Source Type: research
Sex differences in vascular function following antioxidant supplementation
Objectives: Sex differences in cardiovascular disease risk and progression are well established. Estrogen loss following menopause leads to vascular dysfunction, potentially due to elevations in oxidative stress and subsequent decrements in nitric oxide. It is possible a reduction in oxidative stress utilizing an antioxidant supplement could improve vascular function in older females. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: R.M. Kappus, K. Bunsawat, J.M. Haus, T. Baynard, S.A. Phillips, M.D. Brown, B. Fernhall Source Type: research
Pulse wave velocity is increased with experimental sleep restriction in healthy humans
Objectives: Increased carotid-femoral pulse wave velocity is indicative of vascular stiffening of the central arterial tree. Aortic stiffness is a key risk factor for the development of hypertension and cardiovascular disease. Following acute (24-hour) sleep deprivation, healthy adults exhibit an increase in carotid-femoral pulse wave velocity; however, acute sleep deprivation poorly represents sleep patterns observed in everyday life. With this information in mind, we hypothesized a prolonged (9 day) exposure to restricted sleep (4 hours of sleep per night) would result in increases in carotid-femoral pulse wave velocity ...
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Jacqueline K. Limberg, Naima Covassin, Michael J. Joyner, Virend K. Somers Source Type: research
Blood pressure variability and baroreceptor sensitivity in normotensive obese in response to aerobic exercise
Background: Autonomic dysfunction, with increased sympathetic activity at rest has been reported in obese individuals. Indices of blood pressure variability (BPV) and baroreceptor sensitivity (BRS) can provide insight into aspects of autonomic function, particularly following an aerobic exercise bout. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Georgios Grigoriadis, Kanokwan Bunsawat, Bo Fernhall, Tracy Baynard Source Type: research
Role of nitric oxide in β2-adrenergic mediated vasodilation in postmenopausal women
Objectives: Postmenopausal (PM) women have a blunted β2-adrenergic receptor-mediated responsiveness when compared to young premenopausal women in part due to a reduction in the relative contribution of nitric oxide (NO) to β2-adrenergic mediated vasodilation. Hence, we tested the contribution of NO to β2-adrenergic receptor-mediated vasodilation du ring terbutaline infusion. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Sushant M. Ranadive, Rone é E. Harvey, Jacqueline K. Limberg, Timothy B. Curry, Wayne T. Nicholson, Michael J. Joyner Source Type: research
Associations of walking with sarcopenic obesity and cardiovascular disease risk factors in older adults
Objectives: To investigate the associations of walking (steps/day) with sarcopenic obesity (SO) and cardiovascular disease (CVD) risk factors in older adults. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Duck-chul Lee, Nathan F. Meier, Esm ée Bakker Source Type: research
A hydrogen sulfide prodrug augments angiogenesis in a swine model of critical limb ischemia via a nitric oxide dependent mechanism
Introduction: Despite advances in revascularization, treatments for critical limb ischemia (CLI) have been largely unsuccessful. Hydrogen sulfide (H2S) and nitric oxide (NO), are endogenous gasotransmitters which exert potent vasodilatory and proangiogenic effects. Recent experimental evidence suggest that the proangiogenic effects of H2S are medicated in part through the NO pathway. We sought to determine whether a novel H2S prodrug, SG-1002 (Sulfagenix, Inc. Cleveland OH), increases NO production and promotes peripheral revascularization. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Amanda M. Rushing, Amy L. Scarborough, Sarah F. Boisvert, Erminia Donnarumma, Rishi Trivedi, David J. Polhemus, David J. Lefer, Traci T. Goodchild Source Type: research
Body mass index as an independent predictor of change in arterial stiffness parameters with change in body position
Changing from supine to a seated position creates an orthostatic challenge due to the effects of gravity on the distribution of blood. This redistribution of volume unloads baroreceptors and may evoke sympathetic activation. The sympathetic activation may lead to increases in arterial stiffness, but it is unknown as to how different demographic variables may impact these changes. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Elizabeth C. Schroeder, Thessa I.M. Hilgenkamp, Alexander J. Rosenberg, Daniel W. White, Tracy Baynard, Bo Fernhall Source Type: research
A systematic review on the effect of acute aerobic exercise on arterial stiffness reveals a differential response in the upper and lower arterial segments
Objectives: The overall impact of resistance-type exercises and chronic physical activity on the modulation of arterial stiffness has been well characterized; however, the impact of acute aerobic exercise remains unclear. Therefore, we aimed to synthesize evidence pertaining to acute changes in arterial stiffness shortly following aerobic exercise in healthy individuals. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Alexandra B. Cooke, Andrew F. Mutter, Oliver Saleh, Yessica-Haydee Gomez, Stella S. Daskalopoulou Source Type: research
Relationship between step counts and carotid femoral pulse wave velocity in adults treated for hypertension and diabetes
Objectives: ‘Step counts’ captured by wearable physical activity tracking devices are associated with reductions in cardiovascular disease. However, in individuals on cardioprotective medications the impact of step counts may not be captured by the measurement of traditional cardiometabolic risk factors. To address this gap, we aimed to assess the relationship between pedometer-derived step counts and carotid-femoral pulse wave velocity (cfPWV), a summative measure of arterial health. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Kaberi Dasgupta, Alexandra B. Cooke, Ellen Rosenberg, Lawrence Joseph, Stella S. Daskalopoulou Source Type: research
Higher central and brachial systolic blood pressure is selectively associated with weaker cogntive performance in postmenopausal women but not older men
Introduction: Higher aortic stiffness and central blood pressure (BP) are associated with reduced cognitive performance in older adults. Cognitive performance tends to be higher in older women compared with older men, unexplained by differences in years of formal education and/or presence of atherosclerotic vascular disease (AVD). However, whether gender-related differences in cognitive function are explained by alterations in aortic stiffness or central blood pressure (BP) is unclear. We hypothesized that higher aortic stiffness and central systolic BP would be associated with weaker cognitive performance in middle-aged/o...
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: lyndsey E. Dubose, David J. Moser, Taylor Stecklein, Emily Harlynn, William G. Haynes, Gary L. Pierce Source Type: research
