Thoracic aorta PWV assessment by using 4D flow in MRI
Purpose: In MRI, thoracic aorta pulse wave velocity (TAPWV) is usually estimated by 2D phase contrast (PC) with either in plane or through plane velocity acquisition. Thanks to technological improvement, 4D PC with full coverage of the TA and 3 dimension velocity encoding thought time can be now achievable in 10min. Our aim was to compare estimation of TAPWV using 4DPC or 2DPC on healthy volunteer. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Gilles Soulat, Umit Gencer, Nadjia Kachenoura, Konstantinos Stampoulis, Yousef Alattar, Emmanuel Messas, Olivier Villemain, St éphane Laurent, Elie Mousseaux Source Type: research

Near Infrared Spectroscopy (NIRS) can detect improvements in arterial function following 6-months of marathon training
Background: Endurance training improves vascular function and skeletal  muscle perfusion. NIRS can measure changes in oxygenated haemoglobin (oxy-Hb) in the skeletal muscle microvascular bed. Therefore, combined with arterial occlusion, NIRS has the potential to assess microvascular function within skeletal muscle. However, NIRS measurements are strongly influenced by adipose tissue thickness (ATT) at the measurement site. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Siana Jones, Andrew D'Silva, Alun Hughes Source Type: research

Flow-mediated slowing as a novel method for the non-invasive assessment of endothelial function
Background: Flow-mediated slowing (FMS) assesses the slowing of pulse wave velocity (PWV) in response to reactive hyperaemia, to provide a measure of endothelial function. We assessed the reproducibility of FMS  and whether the technique is sensitive to the influence of age. FMS was compared to the commonly used, but technically demanding, alternative measure of endothelial function, flow-mediated dilatation (FMD). (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Amedra Basgaran, Kaisa Maki-Petaja, Ian Wilkinson, Carmel McEniery Source Type: research

Structural and functional arterial abnormalities in fibromuscular dysplasia are in the continuum of hypertension: an imaging and biomechanical study
Fibromuscular dysplasia (FMD) is a non-atherosclerotic non-inflammatory arterial disease of unknown origin. We previously showed the presence of  triple signal (TS) at ultrasound within common carotid artery (CCA) wall. We aimed at coupling TS presence with microconstituents of the vessel wall. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Louise Marais, Pierre Boutouyrie, Hakim Khettab, Chantal Boulanger, Aurelien Lorthioir, Mickael Franck, Ralph Niarra, Jean-Marie Renard, Yann Chambon, Xavier Jeunemaitre, Mustapha Zidi, Pierre-Fran çois Plouin, Stéphane Laurent, Michel Azizi Source Type: research

Vascular phenotyping by means of very high-resolution ultrasound imaging: a feasibility analysis
Background: The study of medium and small-size arteries might be useful in the characterization of vascular adaptation, remodeling and wall ultrastructure modifications occurring with aging and in the presence of cardiovascular risk factors. However, to date, these districts have not been extensively explored non-invasively, due to limited spatial resolution power of standard ultrasound (US) machines. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: N. Di Lascio, R.M. Bruno, V. Gemignani, E. Bianchini, L. Ghiadoni, F. Faita Source Type: research

Optimal automated unobserved office blood pressure protocol: only 6-minutes and two readings may be needed
Background: Automated office blood pressure (AutoBP) involving repeated, unobserved blood pressure (BP) readings during one clinic visit provides a practical alternative to daytime ambulatory blood pressure (ABP). However, the number of reading taken and measurement duration have varied across previously used AutoBP protocols. Therefore, the optimal AutoBP protocol taken in the least amount of time with the fewest BP readings is yet to be determined and was the aim of this study. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Myles Moore, Nathan Dwyer, Ella Hoban, Mark Nelson, Dean Picone, Martin Schultz, James Sharman Source Type: research

Effects of inter-arm differences of brachial systolic blood pressure on the derivation of aortic systolic pressure
Background: Inter-arm differences in brachial systolic blood pressure (SBP) should not theoretically translate to differences in calculated aortic SBP, there being only a single value of aortic blood pressure (BP) at any time. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Alberto Avolio, Davis Theobald, Mitchel Cook, Karen Peebles, Mark Butlin Source Type: research

Use of MicroLife BP watch is a feasible approach to determine inter-arm blood pressure differences in a clinical setting
Aim: The aim of this study is to evaluate the feasibility of Microlife Watch BP for measuring bilateral blood pressure (BP) in a clinical setting. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Christoffer Krogager, Esben Laugesen, Niklas B. Rossen, Per L. Poulsen, Mogens Erlandsen, Klavs W. Hansen Source Type: research

Comparison of blood pressure variability calculated from peripheral and derived aortic blood pressure
Background: Systolic blood pressure variability (SBPV), conventionally calculated from peripheral sites such as the arm or finger, may be of more utility when computed from central aortic values, as this has greater applicability to the heart and the baroreceptor function, due to central location of baroreceptors. As the relationship between aortic and peripheral blood pressure is frequency dependent, particularly in the range of physiological heart rate frequencies, peripheral and aortic SBPV may not be identical. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Zahra Kouchaki, Mark Butlin, Ahmad Qasem, Alberto Avolio Source Type: research

Comparison of arterial stiffness assessed by pOpm ètre® with arterial stiffness assessed by applanation tonometry: a clinical study
Background: Large artery stiffness is recognized as a strong, independent marker of cardiovascular risk, mainly through aortic pulse wave velocity (PWV). pOpm ètre® is a new non-invasive method, which estimates aortic PWV through finger-toe (FT) wave analysis. In a previous study, Alivon et al. have shown an acceptable correlation (r2 = 0.43 for PWV) between pOpmètre® and the reference method Sphygmocor. However this study led to the necessity to opt imize the algorithm and the procedures because of the presence of several outliers involving mainly obese and elderly subjects. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Hasan Obeid, Hakim Khettab, Pierre Boutouyrie, Stephane Laurent, Magid Hallab Source Type: research

Variation of the asymptotic diastolic pressure with different fitting techniques in healthy humans
Background: Reservoir-wave model assumes the measured pressure (Pm) consists of two additive components: reservoir (Pr) and excess pressure (Pex)1-2. Calculation of Pr requires fitting the diastolic decay of Pm for calculating parameters P ∞ (asymptotical value) and b (time constant)1. However, there is no consensus over the value of these parameters1-3-4. Although many investigators use free-fitting, different degrees of freedom (dof) could be used1-2-5. The aim of this study was to examine the effect of varying fitting method on P ∞ ,b and calculate the peaks of Pr and Pex. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Nicola Pomella, Christina Kolyva, Ernst Rietzschel, Patrick Segers, Ashraf W. Khir, Madalina Negoita Source Type: research

Non-invasive estimation of central systolic pressure: a comparison between radial artery tonometry and a new direct central blood pressure estimation method (DCBP)
Background: We have developed a new proprietary method (DCBP ® Direct Central Blood Pressure) to estimate central systolic blood pressure (cSBP) directly from peripheral pressure. In a previous meta-analysis of published high-fidelity pressure studies with simultaneous aortic and brachial pressure recordings, negligible mean difference between DCBP and cSBP has been documented (1). The accuracy and precision of DCBP against arterial tonometry measurements remain to be documented. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Denis Chemla, Sandrine Millasseau, Edmund Lau, Nathalie Richard, Pierre Attal, Mabrouk Brahimi, Alain Nitenberg Source Type: research

Systolic aortic pressure derived from different calibration methods in the general population
Background: There is recent evidence from different research groups that accuracy [1] and prognostic value [2,3,4] of systolic aortic pressure significantly depends on the method of calibration. Although these results consistently show superiority of mean pressure calibration (aSBP2) over both, traditional calibrated aortic systolic (aSBP1) and brachial systolic pressure (bSBP), the investigated cohorts were relatively small and it is still unclear whether the observed associations between pressures are preserved in the general population. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Siegfried Wassertheurer, Bernhard Hametner, Christopher Mayer, Ahmed Hafez, Thomas Weber Source Type: research

Arterial stiffness index beta and cardio-ankle vascular index inherently depend on blood pressure, but can be readily corrected
Objectives: Arterial stiffness index β and cardio-ankle vascular index (CAVI) are widely accepted to quantify the blood pressure (BP)-independent, intrinsic exponent (β0) of the BP-diameter relationship. CAVI and β assume an exponential relationship between pressure (P) and diameter (d). We aim (1) to demonstrate that, under this as sumption, β and CAVI as currently implemented are inherently BP-dependent and (2) to provide corrected, BP-independent forms of CAVI and β. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Bart Spronck, Alberto Avolio, Isabella Tan, Mark Butlin, Koen Reesink, Tammo Delhaas Source Type: research

Hemodynamic correlates of the left ventricular mean ejection pressure: a carotid tonometry study
Background: The systemic arterial load imposed to the left ventricle (LV) is a major determinant of normal/abnormal cardiovascular function. The LV mean ejection pressure (LVMEP) is the best estimate of load faced by the LV throughout ejection. The contribution of the steady and pulsatile blood pressure (BP) component of arterial load to LVMEP is debated. We studied the hemodynamic correlates of LVMEP using carotid tonometry. Intensive care unit patients equipped with an indwelling catheter were studied, thus allowing precise calibration of the tonometer. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Mathieu Jozwiak, Sandrine Millasseau, Jean-Louis Teboul, Jean-Emmanuel Alphonsine, Francois Depret, Nathalie Richard, Pierre Attal, Xavier Monnet, Denis Chemla Source Type: research