Arterial stiffness index beta and cardio-ankle vascular index inherently depend on blood pressure, but can be readily corrected

Objectives: Arterial stiffness index β and cardio-ankle vascular index (CAVI) are widely accepted to quantify the blood pressure (BP)-independent, intrinsic exponent (β0) of the BP-diameter relationship. CAVI and β assume an exponential relationship between pressure (P) and diameter (d). We aim (1) to demonstrate that, under this as sumption, β and CAVI as currently implemented are inherently BP-dependent and (2) to provide corrected, BP-independent forms of CAVI and β.

Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Bart Spronck, Alberto Avolio, Isabella Tan, Mark Butlin, Koen Reesink, Tammo Delhaas Source Type: research