Variation of the asymptotic diastolic pressure with different fitting techniques in healthy humans

Background: Reservoir-wave model assumes the measured pressure (Pm) consists of two additive components: reservoir (Pr) and excess pressure (Pex)1-2. Calculation of Pr requires fitting the diastolic decay of Pm for calculating parameters P ∞ (asymptotical value) and b (time constant)1. However, there is no consensus over the value of these parameters1-3-4. Although many investigators use free-fitting, different degrees of freedom (dof) could be used1-2-5. The aim of this study was to examine the effect of varying fitting method on P ∞ ,b and calculate the peaks of Pr and Pex.

Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Nicola Pomella, Christina Kolyva, Ernst Rietzschel, Patrick Segers, Ashraf W. Khir, Madalina Negoita Source Type: research