Beat-by-beat assessment of cardiac afterload using aortic PU loop – A pilot study
Purpose/Background/Objectives: Cardiac afterload evaluation is crucial during general anesthesia (GA) especially during hypotension episode. Using beat to beat aortic pressure (P) / flow velocity (U) loop constructed from routine signals recorded during GA might allow to track afterload changes. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Arthur Le Gall, Jona Joachim, Joaquim Mateo, Alexandre Mebazaa, Etienne Gayat, Fabrice Vall ée Source Type: research
Measurement of arterial stiffness using a connected bathroom scale: calibration against Sphygmocor
Background: Measurement of arterial stiffness (AS) is still considered difficult. We developed a non-invasive technique to assess AS from a connected bathroom scale, based on ballistocardiography (BCG) and impedance plethysmography (IPG). (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Pierre Boutouyrie, Hakim Khettab, David Campo, Roger Yu, Nadine Buard Source Type: research
Increased cardiac workload in the upright posture in male subjects: non-invasive hemodynamics in men versus women
We examined possible sex-related differences in supine and upright cardiovascular regulation. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Pauliina Kangas, Anna Tahvanainen, Antti Tikkakoski, Jenni Koskela, Marko Uitto, Jari Viik, Mika Kahonen, Tiit Koobi, Emeritus Jukka Mustonen, Ilkka Porsti Source Type: research
Proportional pressure relations in the pulmonary arterial system
Background – Objectives: The pulmonary arterial system can be characterized by: (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Nico Westerhof, Louis Handoko Source Type: research
Mild reduction of glomerular filtration rate is associated with increased systemic vascular resistance independent of changes in cardiac autonomic tone
Objective: Our aim was to evaluate the influence of mild impairment in kidney function on hemodynamics and cardiac autonomic tone. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Ilkka Porsti, Kati Vaaraniemi, Pauliina Kangas, Antti Tikkakoski, Jenni Koskela, Anna Tahvanainen, Arttu Eraranta, Jukka Mustonen Source Type: research
An associated with Familial Hemiplegic Migraine Type 2 mutation in the alpha-2 isoform Na,K-ATPase disturbs vascular responses in mouse brain
Objectives: Migraine attack is associated with severe changes in brain perfusion vasoconstriction-induced hypoxemia during aura and rebound vasodilation in subsequent headache. Familial Hemiplegic Migraine Type 2 is associated with point mutations (including G301R) in the α2 isoform Na,K-ATPase. Heterozygote mice bearing G301R mutation (FHM2) were recently characterized for several behavioral and neuronal abnormalities. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Christian Staehr, Lise Hangaard, Karin Lykke-Hartmann, Elena Bouzinova, Christian Aalkjaer, Vladimir Matchkov Source Type: research
Reversibility of arterial stiffness after kidney transplantation: systematic review and meta-analysis
Background: Chronic kidney disease is associated with increased arterial stiffness. Correction of the uremic milieu by kidney transplantation (KTx) may be improve arterial stiffness. However, results from clinical studies are not uniformly convincing. This could be related to small sample size of studies, heterogeneity in methods and timing of assessment of arterial stiffness after KTx. We aim to measure the reversibility of arterial stiffness after KTx. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Aboubacar Sidibe, Catherine Fortier, Marie-Pier Desjardins, Fabrice Mac-Way, Sacha De Serres, Mohsen Agharazii Source Type: research
High PWV is associated with nano-scale changes in the medial layer of the internal mammary artery
Background: Arterial stiffening occurs as part of the natural ageing process. Degradation of the extracellular matrix (ECM) in the medial layer is typically implicated in arterial stiffening. However, little is known about how localised changes in arteries in terms of both structure and mechanical properties contribute to the overall stiffening of arteries. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Riaz Akhtar, Zhuo Chang, Maria Lyck Hansen, Lars Melholt Rasmussen Source Type: research
Age-dependent telomere attrition, short telomeres and atherosclerosis
Background: Short leukocyte telomere length (LTL) is associated with atherosclerosis. The prevailing view is this association exists since LTL is a biomarker of cumulative inflammation and oxidative stress during adult life. However recent studies show that LTL in adults is defined mainly by LTL at birth and attrition during childhood. Therefore we can suggest that short LTL might precede clinical expression of atherosclerosis. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Simon Toupance, Anna Kearney-Schwartz, Mohamed Temmar, C écile Lakomy, Carlos Labat, Patrick Rossignol, Faiez Zannad, Patrick Lacolley, Abraham Aviv, Athanase Benetos Source Type: research
Cardiovascular consequences of extreme prematurity: a follow-up from the EPICure Study
Background: Long-term outcomes following extremely preterm (EP) birth are becoming increasingly relevant, given improved survival rates. We previously reported altered arterial haemodynamics in 11 year olds who were (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Carmel McEniery, Joanne Beckman, Ian Wilkinson, Neil Marlow, John Cockcroft Source Type: research
Peripheral artery disease and central hemodynamic modification
Peripheral arterial disease (PAD) affects the hemodynamics of the lower limbs1 and is associated with increased cardiovascular risk and mortality2. The aim of this study was to evaluate central hemodynamics and to test the relationships between lower ankle-pressure index (ABI) and Augmentation index (Aix)3,4.In 242 PAD patients (mean age 67 ±9.8years),Augmentation index (Aix) carotid-femoral pulse wave velocity (c-fPWV), pulse pressure amplification (PPA) aortic pulse pressure (aPP) and subendocardial viability ratio (SEVR) weremeasured using applanation tonometry5,6.The ABI values were obtained using an 8-mHz Doppler pro...
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Mariella Catalano, Gabriel Dimitrov, Giovanni Scandale, Marzio Minola, Martino Recchia, Francesca Galli, Maria Carotta, Gianni Carzaniga Source Type: research
Arterial stiffness is associated with low-density non-calcified coronary plaques in patients with type 2 diabetes and healthy controls
Background: Arterial stiffness may provide non-invasive information about cardiovascular risk in patients with type 2 diabetes. We investigated the association between arterial stiffness and subclinical coronary atherosclerosis in patients with type 2 diabetes and healthy controls. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Kristian L. Funck, Esben Laugesen, Kristian Oevrehus, Jesper M. Jensen, Bjarne L. Noergaard, Damini Dey, Troels K. Hansen, Per L. Poulsen Source Type: research
Large and small artery crosstalk in patients with type 2 diabetes
Background: Vascular complications to diabetes mellitus have, traditionally, been divided in to micro- and macroangiopathy. However, a growing body of evidence has put this categorical division into question, as large artery stiffness has been associated with microvascular complications in diabetics, e.g. diabetic retinopathy. The pathophysiology behind this association is poorly understood. The retinal arterioles lack sympathetic innervation and blood supply is autoregulated to accommodate changes in blood pressure and metabolic demand. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Jonathan Mathias Baier, Esben Laugesen, S øren Tang Knudsen, Per Løgstrup Poulsen, Toke Bek Source Type: research
Association between increased arterial stiffness and HbA1c and LDL cholesterol level in type 2 diabetes patients
Background: In patient with type 2 diabetes mellitus (T2DM) the atherosclerosis apper in younger age, in both gender and the cardiovascular risk is much higher. The aim of our study was to examine the association between pulse wave velocity (PWV) and glycated haemoglobin (HbA1c) and low density lipoprotein (LDL-C) level in patient with T2DM. (1,2) (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Ilona Hegyi, Terez Szabo, Eszter Szele, Istvan Vasas Source Type: research
Aortic-brachial stiffness mismatch in patients with arterial hypertension and type 2 diabetes mellitus
Background: Patients with type 2 diabetes have a high risk of CVD. Arterial stiffness gradient is a new prognostic predictor of mortality previously assessed only in dialysis population1-2. (Source: Artery Research)
Source: Artery Research - November 25, 2016 Category: Cardiology Authors: Ekaterina Starostina, Elena Troitskaya, Yulia Kotovskaya, Zhanna Kobalava Source Type: research
